ES438765A1 - Un procedimiento para la preparacion de derivados de prosta-glandinas. - Google Patents

Un procedimiento para la preparacion de derivados de prosta-glandinas.

Info

Publication number
ES438765A1
ES438765A1 ES438765A ES438765A ES438765A1 ES 438765 A1 ES438765 A1 ES 438765A1 ES 438765 A ES438765 A ES 438765A ES 438765 A ES438765 A ES 438765A ES 438765 A1 ES438765 A1 ES 438765A1
Authority
ES
Spain
Prior art keywords
ester
secoprostaglandins
dioxothia
oxothia
thia
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES438765A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of ES438765A1 publication Critical patent/ES438765A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/52—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/16—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C317/18—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton with sulfone or sulfoxide groups bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • C07C317/46—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • C07C317/48—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/004—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
    • C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ES438765A 1974-06-25 1975-06-20 Un procedimiento para la preparacion de derivados de prosta-glandinas. Expired ES438765A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48317874A 1974-06-25 1974-06-25
US56656675A 1975-04-09 1975-04-09

Publications (1)

Publication Number Publication Date
ES438765A1 true ES438765A1 (es) 1977-07-01

Family

ID=27047557

Family Applications (1)

Application Number Title Priority Date Filing Date
ES438765A Expired ES438765A1 (es) 1974-06-25 1975-06-20 Un procedimiento para la preparacion de derivados de prosta-glandinas.

Country Status (16)

Country Link
JP (1) JPS51125020A (xx)
CA (1) CA1064961A (xx)
CH (1) CH614935A5 (xx)
DE (1) DE2528070A1 (xx)
DK (1) DK263775A (xx)
ES (1) ES438765A1 (xx)
FI (1) FI751730A (xx)
FR (1) FR2276037A1 (xx)
GB (1) GB1476262A (xx)
IE (1) IE41258B1 (xx)
IL (1) IL47487A (xx)
LU (1) LU72797A1 (xx)
NL (1) NL7507020A (xx)
NO (1) NO142219C (xx)
NZ (1) NZ177843A (xx)
SE (1) SE7506804L (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2008213666B2 (en) * 2007-02-06 2013-11-07 University Of Louisville Research Foundation, Inc. Substituted alkine derivatives as anti-cancer agents
CA2865487A1 (en) 2011-03-07 2012-09-13 Paula J. Bates Predictive marker of dnmt1 inhibitor therapeutic efficacy and methods of using the marker
WO2014039860A2 (en) 2012-09-07 2014-03-13 University Of Louisville Research Foundation, Inc. Compositions and methods for modulating dnmt1 inhibitor activity

Also Published As

Publication number Publication date
JPS51125020A (en) 1976-11-01
NO752091L (xx) 1975-12-30
NL7507020A (nl) 1975-12-30
IL47487A0 (en) 1975-08-31
GB1476262A (en) 1977-06-10
CA1064961A (en) 1979-10-23
FI751730A (xx) 1975-12-26
SE7506804L (sv) 1975-12-29
DE2528070A1 (de) 1976-01-08
NO142219B (no) 1980-04-08
IE41258B1 (en) 1979-11-21
DK263775A (da) 1975-12-26
IL47487A (en) 1979-05-31
FR2276037B1 (xx) 1979-03-02
NZ177843A (en) 1978-04-03
AU8221675A (en) 1976-12-23
LU72797A1 (xx) 1976-04-13
FR2276037A1 (fr) 1976-01-23
NO142219C (no) 1980-07-16
CH614935A5 (en) 1979-12-28
IE41258L (en) 1975-12-25

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