ES438166A1 - Un procedimiento para la fluoracion electrofila de un com- puesto organico saturado. - Google Patents

Un procedimiento para la fluoracion electrofila de un com- puesto organico saturado.

Info

Publication number
ES438166A1
ES438166A1 ES438166A ES438166A ES438166A1 ES 438166 A1 ES438166 A1 ES 438166A1 ES 438166 A ES438166 A ES 438166A ES 438166 A ES438166 A ES 438166A ES 438166 A1 ES438166 A1 ES 438166A1
Authority
ES
Spain
Prior art keywords
hydrogen atom
fluorine
electrophilically
fluorotrichloromethane
atom
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES438166A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Research Institute for Medicine and Chemistry Inc
Original Assignee
Research Institute for Medicine and Chemistry Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Research Institute for Medicine and Chemistry Inc filed Critical Research Institute for Medicine and Chemistry Inc
Publication of ES438166A1 publication Critical patent/ES438166A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B39/00—Halogenation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
    • C07C17/10—Preparation of halogenated hydrocarbons by replacement by halogens of hydrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
    • C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C07J1/0025—Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of only two carbon atoms, e.g. pregnane derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa
    • C07J7/002—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa not substituted in position 16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/004—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa
    • C07J7/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa substituted in position 16
    • C07J7/0055—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ES438166A 1974-06-04 1975-06-03 Un procedimiento para la fluoracion electrofila de un com- puesto organico saturado. Expired ES438166A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB24734/74A GB1513135A (en) 1974-06-04 1974-06-04 Fluorination process and fluoro steroids

Publications (1)

Publication Number Publication Date
ES438166A1 true ES438166A1 (es) 1977-02-01

Family

ID=10216416

Family Applications (1)

Application Number Title Priority Date Filing Date
ES438166A Expired ES438166A1 (es) 1974-06-04 1975-06-03 Un procedimiento para la fluoracion electrofila de un com- puesto organico saturado.

Country Status (21)

Country Link
US (2) US4036864A (es)
JP (1) JPS514102A (es)
AU (1) AU498203B2 (es)
BE (1) BE829809A (es)
CA (1) CA1064475A (es)
CH (1) CH616397A5 (es)
DE (1) DE2524618A1 (es)
DK (1) DK248075A (es)
ES (1) ES438166A1 (es)
FR (1) FR2275426A1 (es)
GB (1) GB1513135A (es)
IE (1) IE41545B1 (es)
IL (1) IL47418A (es)
IN (1) IN142193B (es)
IT (1) IT1035927B (es)
LU (1) LU72637A1 (es)
NL (1) NL7506547A (es)
NO (1) NO751939L (es)
NZ (1) NZ177688A (es)
SE (1) SE7506339L (es)
ZA (1) ZA753588B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1513135A (en) * 1974-06-04 1978-06-07 Res Inst For Med & Chem Inc Fluorination process and fluoro steroids
US5116599A (en) * 1989-07-31 1992-05-26 Johns Hopkins Univ. Perfluoro-t-butyl-containing compounds for use in fluorine-19 nmr and/or mri
US5234680A (en) * 1989-07-31 1993-08-10 Johns Hopkins Univ. Perfluoro-t-butyl-containing compounds for use in fluorine-19 NMR and/or MRI
EP0870757B1 (en) * 1997-04-10 2002-06-12 Pfizer Inc. Fluoro-substituted adamantane derivatives
DE19738196A1 (de) * 1997-09-02 1999-03-04 Hoechst Ag Verfahren zur Herstellung von Fluor enthaltenden Verbindungen in hoher Reinheit
US6673262B1 (en) * 1997-12-18 2004-01-06 Central Glass Company, Limited Gas for removing deposit and removal method using same
GB9924705D0 (en) * 1999-10-20 1999-12-22 F2 Chemicals Ltd Preparation of selectively fluorinated organic compounds
US6455728B1 (en) 1999-11-01 2002-09-24 Air Products And Chemicals, Inc. Direct fluorination process for preparing high purity 2-fluoro-1,3-dicarbonyl compounds using oxygen as a radical scavenger
US7488847B2 (en) 2002-12-11 2009-02-10 Asahi Glass Company, Limited Fluorinated adamantane and its derivatives
AU2003289036A1 (en) * 2002-12-11 2004-06-30 Asahi Glass Company, Limited Fluorinated adamantane derivatives
EP1757575A4 (en) 2004-06-16 2008-05-07 Asahi Glass Co Ltd FLUORADAMANTANDERIVAT
WO2005123650A1 (ja) * 2004-06-16 2005-12-29 Asahi Glass Company, Limited 新規なフッ素化されたアダマンタン誘導体
US20080275112A1 (en) * 2004-07-23 2008-11-06 Schreiner Peter R Invention Concerning Aminoadamantane Compounds
EP2053055A1 (de) * 2007-10-24 2009-04-29 Bayer Schering Pharma Aktiengesellschaft 11.beta.-Fluoro-3-acetoxyestra-3,5-dien-17-on und Verfahren zu seiner Herstellung
CN112979409B (zh) * 2019-12-13 2022-09-30 浙江省化工研究院有限公司 一种气相催化氯化制备3,3,3-三氯-1,1,1-三氟丙烷的方法
CN116003372A (zh) * 2022-09-14 2023-04-25 多氟多新材料股份有限公司 一种氟代碳酸乙烯酯的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE350020B (es) * 1967-09-11 1972-10-16 Res Inst Medicine Chem
GB1513135A (en) * 1974-06-04 1978-06-07 Res Inst For Med & Chem Inc Fluorination process and fluoro steroids

Also Published As

Publication number Publication date
NO751939L (es) 1975-12-05
GB1513135A (en) 1978-06-07
IT1035927B (it) 1979-10-20
SE7506339L (sv) 1975-12-05
DK248075A (da) 1975-12-05
AU498203B2 (en) 1979-02-22
NL7506547A (nl) 1975-12-08
FR2275426B1 (es) 1979-07-13
CA1064475A (en) 1979-10-16
AU8179575A (en) 1976-12-09
IE41545L (en) 1975-12-04
BE829809A (fr) 1975-12-03
DE2524618A1 (de) 1976-01-02
FR2275426A1 (fr) 1976-01-16
IL47418A0 (en) 1975-08-31
CH616397A5 (es) 1980-03-31
JPS514102A (es) 1976-01-14
LU72637A1 (es) 1976-03-17
IN142193B (es) 1977-06-11
US4284558A (en) 1981-08-18
NZ177688A (en) 1978-03-06
ZA753588B (en) 1976-05-26
IL47418A (en) 1979-11-30
US4036864A (en) 1977-07-19
IE41545B1 (en) 1980-01-30

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