ES437363A1 - Pharmaceutical compositions - Google Patents

Pharmaceutical compositions

Info

Publication number
ES437363A1
ES437363A1 ES437363A ES437363A ES437363A1 ES 437363 A1 ES437363 A1 ES 437363A1 ES 437363 A ES437363 A ES 437363A ES 437363 A ES437363 A ES 437363A ES 437363 A1 ES437363 A1 ES 437363A1
Authority
ES
Spain
Prior art keywords
group
formula
hydrogen atom
substituted
carbon
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES437363A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ABDULFATTAH AL SAYYAB
Original Assignee
ABDULFATTAH AL SAYYAB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ABDULFATTAH AL SAYYAB filed Critical ABDULFATTAH AL SAYYAB
Publication of ES437363A1 publication Critical patent/ES437363A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/53—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)

Abstract

A procedure for the preparation of new Schiff bases of the formula: **(See formula)** where R1 is a hydrogen atom or a lower alkyl group; R2 and R3 are the same or different and each is a hydrogen or halogen atom, a hydroxy group or a lower alkoxy group, or R2 and R3 are attached to adjacent carbon atoms in the benzene nucleus A and together represent a ring carbocyclic fused to benzene nucleus A; R4 is a hydrogen atom, an alkyl or analkyl group or a substituted or unsubstituted aryl group, or R4 together with R3 form a non-aromatic ring fused to the benzene nucleus A, whose non-aromatic ring may in turn be fused to other rings ; R5 is a hydrogen atom, a lower alkyl group, a lower hydroxyalkyl group, or a carboxylic acid group; R6 is a carbon-carbon or carbon-hydrogen bond, a methylene group (-CH2-), a hydroxymethylene group (-CHCH-) or a mercaptomethylene group (-CHSH) and R7 is a hydrogen atom, an alkyl or substituted alkyl group, an aryl or substituted aryl group, or a heterocyclic or substituted heterocyclic group, the process of which is characterized by reacting a carbonyl compound of formula: **(See formula)** where R1, R2, R3 and R4 have the meaning defined above, with an amine of formula: **(See formula)** where R5, R6 and R7 have the meanings defined above, in the presence of a lower alkanol as solvent. (Machine-translation by Google Translate, not legally binding)
ES437363A 1974-05-01 1975-04-30 Pharmaceutical compositions Expired ES437363A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1915774A GB1529564A (en) 1974-05-01 1974-05-01 Pharmaceutical compositions

Publications (1)

Publication Number Publication Date
ES437363A1 true ES437363A1 (en) 1977-05-16

Family

ID=10124714

Family Applications (1)

Application Number Title Priority Date Filing Date
ES437363A Expired ES437363A1 (en) 1974-05-01 1975-04-30 Pharmaceutical compositions

Country Status (11)

Country Link
JP (1) JPS5112933A (en)
AU (1) AU502579B2 (en)
BE (1) BE828530A (en)
CA (1) CA1060438A (en)
DE (1) DE2519193A1 (en)
EG (1) EG12028A (en)
ES (1) ES437363A1 (en)
FR (1) FR2282870A1 (en)
GB (1) GB1529564A (en)
NL (1) NL7505174A (en)
NZ (1) NZ177384A (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2418222A2 (en) * 1975-08-01 1979-09-21 Synthelabo Alpha-phenyl 2-hydroxy-benzylidene amino-alkanoic acid derivs. - and novel di:phenyl-ketone intermediates, useful as anticonvulsants for treating epilepsy
JPS52159599U (en) * 1976-05-27 1977-12-03
JPS5812993Y2 (en) * 1978-07-19 1983-03-12 日本鋼管株式会社 Suspended opening/closing scaffolding device
FR2475543A1 (en) 1980-02-12 1981-08-14 Synthelabo BENZYLIDENIC DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR2544308B1 (en) * 1983-04-14 1985-06-14 Synthelabo SUBSTITUTED ETHINS, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS
NO940195L (en) * 1993-01-25 1994-07-26 Norsk Hydro As New connections

Also Published As

Publication number Publication date
NL7505174A (en) 1975-11-04
NZ177384A (en) 1978-03-06
JPS5112933A (en) 1976-01-31
AU8072175A (en) 1976-11-04
AU502579B2 (en) 1979-08-02
EG12028A (en) 1978-06-30
FR2282870B1 (en) 1978-11-10
FR2282870A1 (en) 1976-03-26
BE828530A (en) 1975-10-29
CA1060438A (en) 1979-08-14
DE2519193A1 (en) 1975-11-20
GB1529564A (en) 1978-10-25

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