ES435689A2 - Procedimiento para la preparacion de 1, 2, 4-triazol-nucleo-sidos. - Google Patents
Procedimiento para la preparacion de 1, 2, 4-triazol-nucleo-sidos.Info
- Publication number
- ES435689A2 ES435689A2 ES435689A ES435689A ES435689A2 ES 435689 A2 ES435689 A2 ES 435689A2 ES 435689 A ES435689 A ES 435689A ES 435689 A ES435689 A ES 435689A ES 435689 A2 ES435689 A2 ES 435689A2
- Authority
- ES
- Spain
- Prior art keywords
- acyl
- ribofuranosyl
- beta
- acid derivatives
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002253 acid Substances 0.000 title abstract 2
- HZCAHMRRMINHDJ-DBRKOABJSA-N ribavirin Natural products O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N1N=CN=C1 HZCAHMRRMINHDJ-DBRKOABJSA-N 0.000 title 2
- HZCAHMRRMINHDJ-MVIOUDGNSA-N 1-(beta-D-ribofuranosyl)-1,2,4-triazole Natural products OC[C@H]1O[C@H]([C@@H](O)[C@@H]1O)n2cncn2 HZCAHMRRMINHDJ-MVIOUDGNSA-N 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 239000002777 nucleoside Substances 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- -1 acyl anhydride Chemical class 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 150000001266 acyl halides Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- CYEBJEDOHLIWNP-UHFFFAOYSA-N methanethioamide Chemical compound NC=S CYEBJEDOHLIWNP-UHFFFAOYSA-N 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/056—Triazole or tetrazole radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/452,065 US3984396A (en) | 1971-06-01 | 1974-03-18 | 1-(β,-D-ribofuranosyl)-1,2,4-triazole acid esters |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES435689A2 true ES435689A2 (es) | 1977-10-16 |
Family
ID=23794869
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES435689A Expired ES435689A2 (es) | 1974-03-18 | 1975-03-17 | Procedimiento para la preparacion de 1, 2, 4-triazol-nucleo-sidos. |
Country Status (13)
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9307043D0 (en) * | 1993-04-05 | 1993-05-26 | Norsk Hydro As | Chemical compounds |
| US6277830B1 (en) | 1998-10-16 | 2001-08-21 | Schering Corporation | 5′-amino acid esters of ribavirin and the use of same to treat hepatitis C with interferon |
| CZ20011130A3 (cs) * | 1998-10-16 | 2001-08-15 | Schering Corporation | Sloučenina, farmaceutický prostředek a jejich použití pro ribavirin-interferon alfa kombinovanou terapii |
| WO2001081359A1 (en) | 2000-04-20 | 2001-11-01 | Schering Corporation | Ribavirin-interferon alfa combination therapy for eradicating detectable hcv-rna in patients having chronic hepatitis c infection |
| JPWO2009028573A1 (ja) | 2007-08-27 | 2010-12-09 | 国立大学法人名古屋大学 | 血液凝固障害におけるリバビリンの利用 |
| US20110045535A1 (en) | 2007-08-27 | 2011-02-24 | National University Corporation Nagoya University | Activator for Blood Coagulation Factor VII Promoter and Utilization of the Same |
| CN111205344B (zh) * | 2020-01-14 | 2023-03-14 | 华东理工大学 | 一种用于甲醇溶剂识别的纯有机磷光小分子材料及其制备方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3798209A (en) * | 1971-06-01 | 1974-03-19 | Icn Pharmaceuticals | 1,2,4-triazole nucleosides |
-
1975
- 1975-03-14 GB GB10724/75A patent/GB1482736A/en not_active Expired
- 1975-03-17 BE BE154411A patent/BE826776R/xx active
- 1975-03-17 ES ES435689A patent/ES435689A2/es not_active Expired
- 1975-03-17 DK DK106375A patent/DK106375A/da unknown
- 1975-03-17 SE SE7502995A patent/SE7502995L/xx unknown
- 1975-03-18 DE DE2560551A patent/DE2560551C2/de not_active Expired
- 1975-03-18 ZA ZA00751662A patent/ZA751662B/xx unknown
- 1975-03-18 YU YU657/75A patent/YU42137B/xx unknown
- 1975-03-18 JP JP50032822A patent/JPS50154253A/ja active Pending
- 1975-03-18 NL NL7503214A patent/NL7503214A/xx not_active Application Discontinuation
- 1975-03-18 DE DE19752511828 patent/DE2511828A1/de active Granted
- 1975-03-18 CA CA222,365A patent/CA1060004A/en not_active Expired
- 1975-03-18 FR FR7508454A patent/FR2264552B1/fr not_active Expired
-
1979
- 1979-03-18 AR AR258018A patent/AR224992A1/es active
-
1985
- 1985-11-19 BE BE0/215890A patent/BE903674Q/fr not_active IP Right Cessation
-
1987
- 1987-01-23 YU YU92/87A patent/YU43291B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK106375A (enrdf_load_stackoverflow) | 1975-09-19 |
| FR2264552A2 (enrdf_load_stackoverflow) | 1975-10-17 |
| AU7914575A (en) | 1976-09-23 |
| AR224992A1 (es) | 1982-02-15 |
| BE903674Q (fr) | 1986-05-20 |
| GB1482736A (en) | 1977-08-10 |
| YU43291B (en) | 1989-06-30 |
| NL7503214A (nl) | 1975-09-22 |
| ZA751662B (en) | 1976-02-25 |
| JPS50154253A (enrdf_load_stackoverflow) | 1975-12-12 |
| DE2511828A1 (de) | 1975-10-02 |
| DE2560551C2 (enrdf_load_stackoverflow) | 1989-02-23 |
| YU42137B (en) | 1988-06-30 |
| YU9287A (en) | 1988-04-30 |
| BE826776R (fr) | 1975-07-16 |
| FR2264552B1 (enrdf_load_stackoverflow) | 1980-12-19 |
| YU65775A (en) | 1983-01-21 |
| SE7502995L (enrdf_load_stackoverflow) | 1975-09-19 |
| DE2511828C2 (enrdf_load_stackoverflow) | 1991-01-17 |
| CA1060004A (en) | 1979-08-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD2A | Announcement of lapse in spain |
Effective date: 20170705 |