ES434384A1 - Live influenza type b virus vaccines and preparation thereof - Google Patents

Live influenza type b virus vaccines and preparation thereof

Info

Publication number
ES434384A1
ES434384A1 ES434384A ES434384A ES434384A1 ES 434384 A1 ES434384 A1 ES 434384A1 ES 434384 A ES434384 A ES 434384A ES 434384 A ES434384 A ES 434384A ES 434384 A1 ES434384 A1 ES 434384A1
Authority
ES
Spain
Prior art keywords
influenza virus
strain
recombinant
attenuated
original
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES434384A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rech Et Ind Therapeutique R I
Original Assignee
Rech Et Ind Therapeutique R I
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rech Et Ind Therapeutique R I filed Critical Rech Et Ind Therapeutique R I
Publication of ES434384A1 publication Critical patent/ES434384A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/543—Mucosal route intranasal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16211—Influenzavirus B, i.e. influenza B virus
    • C12N2760/16234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

A method of preparing a live influenza virus vaccine for nasal administration whose active ingredient comprises at least an effective amount of a recombinant of an attenuated type B influenza virus strain, comprising recombining into a substrate known in the art., which accepts the development of influenza virus type B, an attenuated vaccine-capable strain of influenza virus type B with an isolated product of influenza virus type B and isolate by selective pressure, a recombinant that has at least one marker property of the original attenuated strain that is not shared by the other original strain and by the antigen composition of the other original strain, let said recombinant develop in the allantoic cavity of embryonated chicken eggs, collect the viruses and if You want to add a stabilizer and lyophilize the mixture. (Machine-translation by Google Translate, not legally binding)
ES434384A 1974-02-04 1975-02-01 Live influenza type b virus vaccines and preparation thereof Expired ES434384A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US43917674A 1974-02-04 1974-02-04

Publications (1)

Publication Number Publication Date
ES434384A1 true ES434384A1 (en) 1976-12-01

Family

ID=23743623

Family Applications (1)

Application Number Title Priority Date Filing Date
ES434384A Expired ES434384A1 (en) 1974-02-04 1975-02-01 Live influenza type b virus vaccines and preparation thereof

Country Status (21)

Country Link
JP (1) JPS50107122A (en)
AT (1) AT338416B (en)
BE (1) BE824970A (en)
CA (1) CA1047922A (en)
CH (1) CH596316A5 (en)
CS (1) CS202545B2 (en)
DD (1) DD116474A5 (en)
DE (1) DE2504373A1 (en)
DK (1) DK141926B (en)
ES (1) ES434384A1 (en)
FI (1) FI750260A (en)
FR (1) FR2259616B1 (en)
GB (1) GB1439742A (en)
HU (1) HU170522B (en)
IE (1) IE42043B1 (en)
IL (1) IL46446A (en)
LU (1) LU71784A1 (en)
NL (1) NL7501028A (en)
NO (1) NO750295L (en)
SE (1) SE424503B (en)
ZA (1) ZA75248B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2588918A (en) * 1947-11-07 1952-03-11 William T Graham Mechanism for raising and lowering plow frames relative to the ground wheels
JPS6042209B2 (en) * 1974-05-31 1985-09-20 北里研究所（社団法人） A method for acclimating fresh influenza virus isolates to embryonated chicken eggs in a short period of time

Also Published As

Publication number Publication date
IL46446A (en) 1978-01-31
FR2259616A1 (en) 1975-08-29
ZA75248B (en) 1976-01-28
IE42043B1 (en) 1980-05-21
LU71784A1 (en) 1975-06-24
BE824970A (en) 1975-07-30
NO750295L (en) 1975-09-01
SE7500549L (en) 1975-08-05
JPS50107122A (en) 1975-08-23
SE424503B (en) 1982-07-26
DK9775A (en) 1975-09-29
FI750260A (en) 1975-08-05
DK141926B (en) 1980-07-21
CH596316A5 (en) 1978-03-15
AT338416B (en) 1977-08-25
FR2259616B1 (en) 1980-01-04
CS202545B2 (en) 1981-01-30
DD116474A5 (en) 1975-11-20
GB1439742A (en) 1976-06-16
CA1047922A (en) 1979-02-06
NL7501028A (en) 1975-08-06
DK141926C (en) 1981-01-19
ATA76675A (en) 1976-12-15
AU7734675A (en) 1976-07-15
HU170522B (en) 1977-06-28
IE42043L (en) 1975-08-04
IL46446A0 (en) 1975-04-25
DE2504373A1 (en) 1975-08-07

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