GB1439742A - Live influenza type b virus vaccines and preparation thereof - Google Patents
Live influenza type b virus vaccines and preparation thereofInfo
- Publication number
- GB1439742A GB1439742A GB453575A GB453575A GB1439742A GB 1439742 A GB1439742 A GB 1439742A GB 453575 A GB453575 A GB 453575A GB 453575 A GB453575 A GB 453575A GB 1439742 A GB1439742 A GB 1439742A
- Authority
- GB
- United Kingdom
- Prior art keywords
- strain
- attenuated
- recombinant
- influenza type
- virus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/145—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/543—Mucosal route intranasal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16211—Influenzavirus B, i.e. influenza B virus
- C12N2760/16234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Virology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pulmonology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
1439742 Nasal influenza vaccine RECHERCHE ET INDUSTRIE THERAPEUTIQUES 3 Feb 1975 [4 Feb 1974] 4535/75 Heading A5B A live influenza virus vaccine suitable for nasal administration comprises, as active ingredient an attenuated influenza type B virus strain recombinant obtained from (i) a vaccinal and attenuated influenza type B virus strain and (ii) another influenza type B virus strain, said recombinant having at least one marker property of said attenuated strain which is not shared by said other strain and the antigenic composition of said other strain. The attenuated strain may be Brigit strain. The recombinant may be influenza type BR5, R22 or R22 strain (ATCC VR787, 788 and 789 respectively). The recombinant may be prepared by combining the attenuated strain and the other strain in the allantoic cavity of embryonated chicken eggs, and isolating the recombinant by selective pressure. The isolate may be grown in the allantoic cavity of chicken eggs, admixed with a stabilizer, e.g. peptone or sugar, and freeze-dried. The vaccine may also include an attenuated influenza type A virus vaccine, e.g. Alice strain (ATCC VR776).
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US43917674A | 1974-02-04 | 1974-02-04 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1439742A true GB1439742A (en) | 1976-06-16 |
Family
ID=23743623
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB453575A Expired GB1439742A (en) | 1974-02-04 | 1975-02-03 | Live influenza type b virus vaccines and preparation thereof |
Country Status (21)
Country | Link |
---|---|
JP (1) | JPS50107122A (en) |
AT (1) | AT338416B (en) |
BE (1) | BE824970A (en) |
CA (1) | CA1047922A (en) |
CH (1) | CH596316A5 (en) |
CS (1) | CS202545B2 (en) |
DD (1) | DD116474A5 (en) |
DE (1) | DE2504373A1 (en) |
DK (1) | DK141926B (en) |
ES (1) | ES434384A1 (en) |
FI (1) | FI750260A (en) |
FR (1) | FR2259616B1 (en) |
GB (1) | GB1439742A (en) |
HU (1) | HU170522B (en) |
IE (1) | IE42043B1 (en) |
IL (1) | IL46446A (en) |
LU (1) | LU71784A1 (en) |
NL (1) | NL7501028A (en) |
NO (1) | NO750295L (en) |
SE (1) | SE424503B (en) |
ZA (1) | ZA75248B (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2588918A (en) * | 1947-11-07 | 1952-03-11 | William T Graham | Mechanism for raising and lowering plow frames relative to the ground wheels |
JPS6042209B2 (en) * | 1974-05-31 | 1985-09-20 | 北里研究所(社団法人) | A method for acclimating fresh influenza virus isolates to embryonated chicken eggs in a short period of time |
-
1975
- 1975-01-14 ZA ZA00750248A patent/ZA75248B/en unknown
- 1975-01-16 DK DK9775AA patent/DK141926B/en not_active IP Right Cessation
- 1975-01-16 IL IL46446A patent/IL46446A/en unknown
- 1975-01-20 SE SE7500549A patent/SE424503B/en unknown
- 1975-01-23 CA CA218,508A patent/CA1047922A/en not_active Expired
- 1975-01-24 FR FR7502331A patent/FR2259616B1/fr not_active Expired
- 1975-01-27 IE IE160/75A patent/IE42043B1/en unknown
- 1975-01-29 NL NL7501028A patent/NL7501028A/en not_active Application Discontinuation
- 1975-01-30 NO NO750295A patent/NO750295L/no unknown
- 1975-01-30 BE BE152864A patent/BE824970A/en not_active IP Right Cessation
- 1975-01-31 FI FI750260A patent/FI750260A/fi not_active Application Discontinuation
- 1975-02-01 ES ES434384A patent/ES434384A1/en not_active Expired
- 1975-02-03 LU LU71784A patent/LU71784A1/xx unknown
- 1975-02-03 AT AT76675A patent/AT338416B/en not_active IP Right Cessation
- 1975-02-03 DD DD183973A patent/DD116474A5/xx unknown
- 1975-02-03 DE DE19752504373 patent/DE2504373A1/en not_active Withdrawn
- 1975-02-03 CS CS75669A patent/CS202545B2/en unknown
- 1975-02-03 JP JP50014790A patent/JPS50107122A/ja active Pending
- 1975-02-03 HU HUTE805A patent/HU170522B/hu unknown
- 1975-02-03 CH CH124275A patent/CH596316A5/xx not_active IP Right Cessation
- 1975-02-03 GB GB453575A patent/GB1439742A/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
IL46446A (en) | 1978-01-31 |
FR2259616A1 (en) | 1975-08-29 |
ZA75248B (en) | 1976-01-28 |
IE42043B1 (en) | 1980-05-21 |
ES434384A1 (en) | 1976-12-01 |
LU71784A1 (en) | 1975-06-24 |
BE824970A (en) | 1975-07-30 |
NO750295L (en) | 1975-09-01 |
SE7500549L (en) | 1975-08-05 |
JPS50107122A (en) | 1975-08-23 |
SE424503B (en) | 1982-07-26 |
DK9775A (en) | 1975-09-29 |
FI750260A (en) | 1975-08-05 |
DK141926B (en) | 1980-07-21 |
CH596316A5 (en) | 1978-03-15 |
AT338416B (en) | 1977-08-25 |
FR2259616B1 (en) | 1980-01-04 |
CS202545B2 (en) | 1981-01-30 |
DD116474A5 (en) | 1975-11-20 |
CA1047922A (en) | 1979-02-06 |
NL7501028A (en) | 1975-08-06 |
DK141926C (en) | 1981-01-19 |
ATA76675A (en) | 1976-12-15 |
AU7734675A (en) | 1976-07-15 |
HU170522B (en) | 1977-06-28 |
IE42043L (en) | 1975-08-04 |
IL46446A0 (en) | 1975-04-25 |
DE2504373A1 (en) | 1975-08-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed [section 19, patents act 1949] | ||
PCNP | Patent ceased through non-payment of renewal fee |