ES433995A1 - Procedimiento para purificar una cefalosporina. - Google Patents

Procedimiento para purificar una cefalosporina.

Info

Publication number
ES433995A1
ES433995A1 ES433995A ES433995A ES433995A1 ES 433995 A1 ES433995 A1 ES 433995A1 ES 433995 A ES433995 A ES 433995A ES 433995 A ES433995 A ES 433995A ES 433995 A1 ES433995 A1 ES 433995A1
Authority
ES
Spain
Prior art keywords
carboxylic acid
salt
adsorbent
aqueous solution
cephalosporin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES433995A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline LLC
Original Assignee
SmithKline Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Corp filed Critical SmithKline Corp
Publication of ES433995A1 publication Critical patent/ES433995A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36Methylene radicals, substituted by sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02Preparation
    • C07D501/12Separation; Purification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Peptides Or Proteins (AREA)
ES433995A 1974-01-23 1975-01-21 Procedimiento para purificar una cefalosporina. Expired ES433995A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US43591174A 1974-01-23 1974-01-23

Publications (1)

Publication Number Publication Date
ES433995A1 true ES433995A1 (es) 1976-11-16

Family

ID=23730331

Family Applications (1)

Application Number Title Priority Date Filing Date
ES433995A Expired ES433995A1 (es) 1974-01-23 1975-01-21 Procedimiento para purificar una cefalosporina.

Country Status (9)

Country Link
JP (1) JPS50106996A (nl)
BE (1) BE824028A (nl)
CH (1) CH613971A5 (nl)
DE (1) DE2502097A1 (nl)
ES (1) ES433995A1 (nl)
FR (1) FR2258388B1 (nl)
GB (1) GB1472966A (nl)
IE (1) IE40481B1 (nl)
NL (1) NL7500805A (nl)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5398989A (en) * 1977-02-09 1978-08-29 Fujisawa Pharmaceut Co Ltd Purification of cephalosporin compounds
US4115644A (en) * 1977-09-19 1978-09-19 Eli Lilly And Company Process for preparing pure cefamandole from alkali metal and ammonium salts thereof
JPS5665894A (en) * 1979-10-31 1981-06-03 Asahi Chem Ind Co Ltd Purification of 7-aminocephalosporanic acid derivative
JPS60161990A (ja) * 1984-02-02 1985-08-23 Shionogi & Co Ltd オキサセフアロスポリンの精製法
GB8406218D0 (en) * 1984-03-09 1984-04-11 Glaxo Group Ltd Process
ES2130532T3 (es) * 1994-08-17 1999-07-01 Gen Electric Procedimiento de adsorcion para la recuperacion de amina o sal de amina de soluciones acuosas de salmuera.
JPH10101679A (ja) * 1996-10-02 1998-04-21 Otsuka Chem Co Ltd セファゾリンの製造法
KR100748387B1 (ko) * 1997-06-04 2007-08-10 산도즈 게엠베하 7-아미노세팔로스포란산(7-aca)의 개선된 침전 방법
CN104610282B (zh) * 2015-02-14 2017-03-15 石药集团中诺药业(石家庄)有限公司 一种头孢唑啉酸的提纯方法

Also Published As

Publication number Publication date
JPS50106996A (nl) 1975-08-22
BE824028A (fr) 1975-06-30
CH613971A5 (en) 1979-10-31
FR2258388A1 (nl) 1975-08-18
GB1472966A (en) 1977-05-11
IE40481L (en) 1975-07-23
DE2502097A1 (de) 1975-07-24
IE40481B1 (en) 1979-06-06
NL7500805A (nl) 1975-07-25
FR2258388B1 (nl) 1978-07-07

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