ES430759A1 - Procedimiento para preparar derivados de isoquinolina. - Google Patents
Procedimiento para preparar derivados de isoquinolina.Info
- Publication number
- ES430759A1 ES430759A1 ES430759A ES430759A ES430759A1 ES 430759 A1 ES430759 A1 ES 430759A1 ES 430759 A ES430759 A ES 430759A ES 430759 A ES430759 A ES 430759A ES 430759 A1 ES430759 A1 ES 430759A1
- Authority
- ES
- Spain
- Prior art keywords
- carbon atoms
- alkyl
- alkoxy
- formula
- halogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000002537 isoquinolines Chemical class 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 13
- 125000000217 alkyl group Chemical group 0.000 abstract 6
- 125000003545 alkoxy group Chemical group 0.000 abstract 4
- 150000002367 halogens Chemical group 0.000 abstract 3
- 125000000094 2-phenylethyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])* 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000002183 isoquinolinyl group Chemical class C1(=NC=CC2=CC=CC=C12)* 0.000 abstract 2
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- 125000005073 adamantyl group Chemical group C12(CC3CC(CC(C1)C3)C2)* 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Substances 0.000 abstract 1
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D263/06—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by oxygen atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1430773A CH581113A5 (en, 2012) | 1973-10-08 | 1973-10-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES430759A1 true ES430759A1 (es) | 1977-04-16 |
Family
ID=4399720
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES430759A Expired ES430759A1 (es) | 1973-10-08 | 1974-10-07 | Procedimiento para preparar derivados de isoquinolina. |
Country Status (21)
| Country | Link |
|---|---|
| JP (1) | JPS5082078A (en, 2012) |
| AT (1) | ATA802974A (en, 2012) |
| AU (2) | AU498889B2 (en, 2012) |
| BE (1) | BE820789A (en, 2012) |
| CA (1) | CA1021772A (en, 2012) |
| CH (1) | CH581113A5 (en, 2012) |
| DD (1) | DD114605A5 (en, 2012) |
| DE (1) | DE2447756A1 (en, 2012) |
| DK (1) | DK135766B (en, 2012) |
| ES (1) | ES430759A1 (en, 2012) |
| FI (1) | FI286374A7 (en, 2012) |
| FR (1) | FR2247242B1 (en, 2012) |
| GB (1) | GB1474775A (en, 2012) |
| HU (1) | HU169126B (en, 2012) |
| IL (1) | IL45797A (en, 2012) |
| NL (1) | NL7413105A (en, 2012) |
| NO (1) | NO743534L (en, 2012) |
| PH (1) | PH11611A (en, 2012) |
| SE (1) | SE7412310L (en, 2012) |
| SU (1) | SU567403A3 (en, 2012) |
| ZA (1) | ZA746409B (en, 2012) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE7603371L (sv) * | 1975-03-26 | 1976-09-27 | Sandoz Ag | Organiska foreningar, deras anvendning och framstellning |
| US4129565A (en) * | 1975-07-11 | 1978-12-12 | Nisshin Flour Milling Co., Ltd. | Isocarbostyril derivatives |
| DK166478A (da) * | 1977-05-02 | 1978-11-03 | Merck & Co Inc | Fremgangsmaade til fremstilling af naphthyridiner |
| EP0711804A3 (de) | 1994-11-14 | 1999-09-22 | Ciba SC Holding AG | Kryptolichtschutzmittel |
| US6346536B1 (en) | 1997-09-03 | 2002-02-12 | Guilford Pharmaceuticals Inc. | Poly(ADP-ribose) polymerase inhibitors and method for treating neural or cardiovascular tissue damage using the same |
| US6197785B1 (en) * | 1997-09-03 | 2001-03-06 | Guilford Pharmaceuticals Inc. | Alkoxy-substituted compounds, methods, and compositions for inhibiting PARP activity |
| US6635642B1 (en) | 1997-09-03 | 2003-10-21 | Guilford Pharmaceuticals Inc. | PARP inhibitors, pharmaceutical compositions comprising same, and methods of using same |
| US6291425B1 (en) | 1999-09-01 | 2001-09-18 | Guilford Pharmaceuticals Inc. | Compounds, methods and pharmaceutical compositions for treating cellular damage, such as neural or cardiovascular tissue damage |
| US6426415B1 (en) | 1997-09-03 | 2002-07-30 | Guilford Pharmaceuticals Inc. | Alkoxy-substituted compounds, methods and compositions for inhibiting parp activity |
| US6514983B1 (en) | 1997-09-03 | 2003-02-04 | Guilford Pharmaceuticals Inc. | Compounds, methods and pharmaceutical compositions for treating neural or cardiovascular tissue damage |
| US6395749B1 (en) | 1998-05-15 | 2002-05-28 | Guilford Pharmaceuticals Inc. | Carboxamide compounds, methods, and compositions for inhibiting PARP activity |
| US6387902B1 (en) | 1998-12-31 | 2002-05-14 | Guilford Pharmaceuticals, Inc. | Phenazine compounds, methods and pharmaceutical compositions for inhibiting PARP |
| US6723733B2 (en) | 2000-05-19 | 2004-04-20 | Guilford Pharmaceuticals, Inc. | Sulfonamide and carbamide derivatives of 6(5H)phenanthridinones and their uses |
| AU2001275085A1 (en) | 2000-06-01 | 2001-12-11 | Guilford Pharmaceuticals Inc. | Methods, compounds and compositions for treating gout |
| WO2025016273A1 (zh) * | 2023-07-14 | 2025-01-23 | 拜西欧斯（北京）生物技术有限公司 | 异喹啉衍生物、包含其的药物组合物以及它们的用途 |
-
1973
- 1973-10-08 CH CH1430773A patent/CH581113A5/xx not_active IP Right Cessation
-
1974
- 1974-09-30 DK DK514874AA patent/DK135766B/da unknown
- 1974-09-30 SE SE7412310A patent/SE7412310L/xx unknown
- 1974-09-30 NO NO743534A patent/NO743534L/no unknown
- 1974-10-01 FI FI2863/74A patent/FI286374A7/fi unknown
- 1974-10-03 GB GB4290974A patent/GB1474775A/en not_active Expired
- 1974-10-04 NL NL7413105A patent/NL7413105A/xx not_active Application Discontinuation
- 1974-10-04 DD DD181520A patent/DD114605A5/xx unknown
- 1974-10-07 AT AT802974A patent/ATA802974A/de not_active Application Discontinuation
- 1974-10-07 IL IL45797A patent/IL45797A/xx unknown
- 1974-10-07 JP JP49114815A patent/JPS5082078A/ja active Pending
- 1974-10-07 ES ES430759A patent/ES430759A1/es not_active Expired
- 1974-10-07 BE BE149290A patent/BE820789A/xx unknown
- 1974-10-07 CA CA210,857A patent/CA1021772A/en not_active Expired
- 1974-10-07 PH PH16382A patent/PH11611A/en unknown
- 1974-10-07 DE DE19742447756 patent/DE2447756A1/de not_active Withdrawn
- 1974-10-08 ZA ZA00746409A patent/ZA746409B/xx unknown
- 1974-10-08 AU AU74090/74A patent/AU498889B2/en not_active Expired
- 1974-10-08 FR FR7433761A patent/FR2247242B1/fr not_active Expired
- 1974-10-08 HU HUSA2697A patent/HU169126B/hu unknown
- 1974-10-08 SU SU7402066522A patent/SU567403A3/ru active
- 1974-10-09 AU AU74130/74A patent/AU7413074A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DK135766B (da) | 1977-06-20 |
| DK514874A (en, 2012) | 1975-06-09 |
| SE7412310L (en, 2012) | 1975-04-09 |
| ZA746409B (en) | 1976-05-26 |
| FR2247242B1 (en, 2012) | 1978-07-21 |
| FI286374A7 (en, 2012) | 1975-04-09 |
| DD114605A5 (en, 2012) | 1975-08-12 |
| AU7408974A (en) | 1976-04-15 |
| JPS5082078A (en, 2012) | 1975-07-03 |
| AU7409074A (en) | 1976-04-15 |
| PH11611A (en) | 1978-04-12 |
| IL45797A0 (en) | 1974-12-31 |
| AU7413074A (en) | 1976-04-15 |
| DE2447756A1 (de) | 1975-04-10 |
| SU567403A3 (ru) | 1977-07-30 |
| CA1021772A (en) | 1977-11-29 |
| AU498889B2 (en) | 1979-03-29 |
| HU169126B (en, 2012) | 1976-09-28 |
| DK135766C (en, 2012) | 1977-11-21 |
| NL7413105A (nl) | 1975-04-10 |
| FR2247242A1 (en, 2012) | 1975-05-09 |
| NO743534L (en, 2012) | 1975-05-05 |
| BE820789A (fr) | 1975-04-07 |
| ATA802974A (de) | 1979-07-15 |
| CH581113A5 (en, 2012) | 1976-10-29 |
| IL45797A (en) | 1978-04-30 |
| GB1474775A (en) | 1977-05-25 |
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