ES428267A1 - Procedimiento para la produccion de derivados de guanidina. - Google Patents
Procedimiento para la produccion de derivados de guanidina.Info
- Publication number
- ES428267A1 ES428267A1 ES428267A ES428267A ES428267A1 ES 428267 A1 ES428267 A1 ES 428267A1 ES 428267 A ES428267 A ES 428267A ES 428267 A ES428267 A ES 428267A ES 428267 A1 ES428267 A1 ES 428267A1
- Authority
- ES
- Spain
- Prior art keywords
- carbon atoms
- hydrogen
- alkyl
- chlorine
- procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- ZRALSGWEFCBTJO-UHFFFAOYSA-N Guanidine Chemical class NC(N)=N ZRALSGWEFCBTJO-UHFFFAOYSA-N 0.000 title 1
- 229940083094 guanine derivative acting on arteriolar smooth muscle Drugs 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 8
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- 239000001257 hydrogen Substances 0.000 abstract 5
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 5
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 229910052801 chlorine Inorganic materials 0.000 abstract 3
- 239000000460 chlorine Substances 0.000 abstract 3
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 2
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Chemical group BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 2
- 229910052794 bromium Chemical group 0.000 abstract 2
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- 125000003884 phenylalkyl group Chemical group 0.000 abstract 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical compound [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
- 125000004036 acetal group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000002816 methylsulfanyl group Chemical group [H]C([H])([H])S[*] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/90—Benzo [c, d] indoles; Hydrogenated benzo [c, d] indoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1032873A CH581108A5 (en) | 1973-07-16 | 1973-07-16 | Hexahydro-benzo(c,d)indol-1-yl-N''-hydroxyguinidine derivs - including acetals, salidiuretics, prepd from corresp benzo-indolyl-isothioureas |
| CH1032773A CH589625A5 (en) | 1973-07-16 | 1973-07-16 | Hexahydro-benzo(c,d)indol-1-yl-N''-hydroxyguinidine derivs - including acetals, salidiuretics, prepd from corresp benzo-indolyl-isothioureas |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES428267A1 true ES428267A1 (es) | 1977-02-16 |
Family
ID=25706354
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES428267A Expired ES428267A1 (es) | 1973-07-16 | 1974-07-15 | Procedimiento para la produccion de derivados de guanidina. |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4057560A (forum.php) |
| JP (1) | JPS5037773A (forum.php) |
| AT (1) | ATA582674A (forum.php) |
| AU (1) | AU7128774A (forum.php) |
| DD (1) | DD112125A5 (forum.php) |
| DE (1) | DE2433308A1 (forum.php) |
| DK (1) | DK365974A (forum.php) |
| ES (1) | ES428267A1 (forum.php) |
| FI (1) | FI206974A7 (forum.php) |
| FR (1) | FR2237627B1 (forum.php) |
| GB (1) | GB1474133A (forum.php) |
| HU (1) | HU168858B (forum.php) |
| IL (1) | IL45265A0 (forum.php) |
| NL (1) | NL7409441A (forum.php) |
| NO (1) | NO742478L (forum.php) |
| SE (1) | SE7408978L (forum.php) |
| YU (1) | YU197474A (forum.php) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5302612A (en) * | 1990-02-26 | 1994-04-12 | Eli Lilly And Company | 6-substituted-hexahydrobenz[cd]indoles |
| US5229410A (en) * | 1990-08-15 | 1993-07-20 | Eli Lilly And Company | 6-substituted-hexahydrobenz[cd]indoles |
| US5229409A (en) * | 1990-08-15 | 1993-07-20 | Eli Lilly And Company | 6-substituted-tetrahydrobenz[cd]indoles |
| US5364856A (en) * | 1991-03-28 | 1994-11-15 | Eli Lilly And Company | 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz[CD]indoles |
| US5244911A (en) * | 1991-03-28 | 1993-09-14 | Eli Lilly And Company | 6-heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz(cd)indoles and pharmaceutical use thereof |
| US5244912A (en) * | 1991-03-28 | 1993-09-14 | Eli Lilly And Company | 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz(cd)indoles and pharmaceutical use thereof |
| US5641794A (en) * | 1991-03-28 | 1997-06-24 | Eli Lilly Company | 6-heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz[cd]indoles |
| US5347013A (en) * | 1991-03-28 | 1994-09-13 | Eli Lilly And Company | 6-heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz[cd]indoles |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3030378A (en) * | 1959-05-29 | 1962-04-17 | Ciba Pharmaccutical Products I | Five-membered nu-heterocyclic guanidines |
| US3304306A (en) * | 1964-01-02 | 1967-02-14 | Ciba Geigy Corp | Nu (amidino-lower alkyl)-benzhydryl piperidines |
| CH517730A (de) * | 1969-10-24 | 1972-01-15 | Sandoz Ag | Verfahren zur Herstellung neuer Guanidin-Verbindungen |
| BE757879A (fr) * | 1969-10-24 | 1971-04-22 | Sandoz Sa | Derives du benzo(cd)indole, leur preparation et medicaments contenant ces derives |
| CH517732A (de) * | 1969-10-24 | 1972-01-15 | Sandoz Ag | Verfahren zur Herstellung neuer Guanidin- Verbindungen |
-
1974
- 1974-07-05 FI FI2069/74A patent/FI206974A7/fi unknown
- 1974-07-08 DK DK365974A patent/DK365974A/da unknown
- 1974-07-08 SE SE7408978A patent/SE7408978L/xx unknown
- 1974-07-08 NO NO742478A patent/NO742478L/no unknown
- 1974-07-10 US US05/487,194 patent/US4057560A/en not_active Expired - Lifetime
- 1974-07-11 DE DE2433308A patent/DE2433308A1/de active Pending
- 1974-07-12 NL NL7409441A patent/NL7409441A/xx unknown
- 1974-07-15 DD DD179923A patent/DD112125A5/xx unknown
- 1974-07-15 ES ES428267A patent/ES428267A1/es not_active Expired
- 1974-07-15 YU YU01974/74A patent/YU197474A/xx unknown
- 1974-07-15 AT AT582674A patent/ATA582674A/de not_active Application Discontinuation
- 1974-07-15 JP JP49080290A patent/JPS5037773A/ja active Pending
- 1974-07-15 HU HUSA2673A patent/HU168858B/hu unknown
- 1974-07-15 IL IL45265A patent/IL45265A0/xx unknown
- 1974-07-16 FR FR7424627A patent/FR2237627B1/fr not_active Expired
- 1974-07-16 AU AU71287/74A patent/AU7128774A/en not_active Expired
- 1974-07-16 GB GB3140774A patent/GB1474133A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AU7128774A (en) | 1976-01-22 |
| DK365974A (forum.php) | 1975-03-17 |
| FR2237627A1 (forum.php) | 1975-02-14 |
| JPS5037773A (forum.php) | 1975-04-08 |
| DD112125A5 (forum.php) | 1975-03-20 |
| SE7408978L (sv) | 1975-01-17 |
| GB1474133A (en) | 1977-05-18 |
| ATA582674A (de) | 1978-03-15 |
| US4057560A (en) | 1977-11-08 |
| DE2433308A1 (de) | 1975-02-06 |
| YU197474A (en) | 1982-05-31 |
| IL45265A0 (en) | 1974-10-22 |
| HU168858B (forum.php) | 1976-07-28 |
| FR2237627B1 (forum.php) | 1978-07-21 |
| FI206974A7 (forum.php) | 1975-01-17 |
| NL7409441A (nl) | 1975-01-20 |
| NO742478L (forum.php) | 1975-02-10 |
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