ES426436A1 - Procedimiento para la obtencion de derivados de la 3,3-bis (4-hidroxifenil)-2-indolinona. - Google Patents

Procedimiento para la obtencion de derivados de la 3,3-bis (4-hidroxifenil)-2-indolinona.

Info

Publication number
ES426436A1
ES426436A1 ES426436A ES426436A ES426436A1 ES 426436 A1 ES426436 A1 ES 426436A1 ES 426436 A ES426436 A ES 426436A ES 426436 A ES426436 A ES 426436A ES 426436 A1 ES426436 A1 ES 426436A1
Authority
ES
Spain
Prior art keywords
hydroxyphenyl
bis
indolinone
chloride
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES426436A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dr Andreu SA
Original Assignee
Dr Andreu SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Andreu SA filed Critical Dr Andreu SA
Priority to ES426436A priority Critical patent/ES426436A1/es
Priority to US05/573,406 priority patent/US4053483A/en
Priority to GB1949275A priority patent/GB1455100A/en
Priority to FR7514888A priority patent/FR2270865B1/fr
Priority to CH625275A priority patent/CH605747A5/xx
Priority to JP50057486A priority patent/JPS50154242A/ja
Priority to AR258828A priority patent/AR209303A1/es
Priority to DE2521966A priority patent/DE2521966C3/de
Publication of ES426436A1 publication Critical patent/ES426436A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/38—Oxygen atoms in positions 2 and 3, e.g. isatin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES426436A 1974-05-18 1974-05-18 Procedimiento para la obtencion de derivados de la 3,3-bis (4-hidroxifenil)-2-indolinona. Expired ES426436A1 (es)

Priority Applications (8)

Application Number Priority Date Filing Date Title
ES426436A ES426436A1 (es) 1974-05-18 1974-05-18 Procedimiento para la obtencion de derivados de la 3,3-bis (4-hidroxifenil)-2-indolinona.
US05/573,406 US4053483A (en) 1974-05-18 1975-05-01 Derivatives of 3,3-bis-(4-hydroxyphenyl)-2-indolinone and process for the preparation thereof
GB1949275A GB1455100A (en) 1974-05-18 1975-05-08 Derivatives of 3,3-bis-4-hydroxyphenyl-2-indolinone and process for the preparation thereof
FR7514888A FR2270865B1 (es) 1974-05-18 1975-05-13
CH625275A CH605747A5 (es) 1974-05-18 1975-05-15
JP50057486A JPS50154242A (es) 1974-05-18 1975-05-16
AR258828A AR209303A1 (es) 1974-05-18 1975-05-16 Procedimiento para la obtencion de derivados de la 3,3-bis-(4-hidroxifenil)-2-indolinona
DE2521966A DE2521966C3 (de) 1974-05-18 1975-05-16 33-Bis-(4-hydroxyphenyl)-7-methyl-2-indolinon-Derivate, deren Salze und Verfahren zu deren Herstellung

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES426436A ES426436A1 (es) 1974-05-18 1974-05-18 Procedimiento para la obtencion de derivados de la 3,3-bis (4-hidroxifenil)-2-indolinona.

Publications (1)

Publication Number Publication Date
ES426436A1 true ES426436A1 (es) 1976-07-01

Family

ID=8466710

Family Applications (1)

Application Number Title Priority Date Filing Date
ES426436A Expired ES426436A1 (es) 1974-05-18 1974-05-18 Procedimiento para la obtencion de derivados de la 3,3-bis (4-hidroxifenil)-2-indolinona.

Country Status (8)

Country Link
US (1) US4053483A (es)
JP (1) JPS50154242A (es)
AR (1) AR209303A1 (es)
CH (1) CH605747A5 (es)
DE (1) DE2521966C3 (es)
ES (1) ES426436A1 (es)
FR (1) FR2270865B1 (es)
GB (1) GB1455100A (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3529994A1 (de) * 1985-08-22 1987-02-26 Hoechst Ag Indolinonderivate, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung
US4760083A (en) * 1986-04-10 1988-07-26 E. I. Dupont De Nemours & Company 3,3-disubstituted indolines
CA2478172A1 (en) * 2002-03-15 2003-09-25 Eli Lilly And Company Dihydroindol-2-one derivatives as steroid hormone nuclear receptor modulators
CA2555812A1 (en) * 2004-02-13 2005-09-01 President And Fellows Of Harvard College 3-3-di-substituted-oxindoles as inhibitors of translation initiation
KR20060130781A (ko) * 2004-04-08 2006-12-19 토포타겟 에이/에스 다이페닐 인돌-2-온 화합물 및 암 치료에 있어서의 그의용도
JP2010512355A (ja) * 2006-12-11 2010-04-22 トポターゲット・アクティーゼルスカブ 癌の処置のためのジフェニルオキシ−インドール−２−オン化合物のプロドラッグ
WO2010109008A1 (en) 2009-03-26 2010-09-30 Topotarget A/S Prodrugs of substituted 3-(4-hydroxyphenyl)-indolin-2-ones
WO2014113820A1 (en) * 2013-01-18 2014-07-24 Shapiro David J Estrogen receptor inhibitors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1292472A (en) * 1970-06-16 1972-10-11 Prodotti Antibiotici Spa Esters of diphenolic substances
US3901912A (en) * 1970-06-16 1975-08-26 Prodotti Antibiotici Spa 3,3-bis-(p-phosphonoxy- and p-sulphoxy-phenyl)-2-indolinones

Also Published As

Publication number Publication date
DE2521966C3 (de) 1980-04-30
JPS50154242A (es) 1975-12-12
US4053483A (en) 1977-10-11
FR2270865B1 (es) 1979-07-20
FR2270865A1 (es) 1975-12-12
DE2521966A1 (de) 1975-11-27
AR209303A1 (es) 1977-04-15
GB1455100A (en) 1976-11-10
CH605747A5 (es) 1978-10-13
DE2521966B2 (de) 1979-08-23

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