GB1292472A - Esters of diphenolic substances - Google Patents

Esters of diphenolic substances

Info

Publication number
GB1292472A
GB1292472A GB29047/70A GB2904770A GB1292472A GB 1292472 A GB1292472 A GB 1292472A GB 29047/70 A GB29047/70 A GB 29047/70A GB 2904770 A GB2904770 A GB 2904770A GB 1292472 A GB1292472 A GB 1292472A
Authority
GB
United Kingdom
Prior art keywords
sulpho
signifies
spa
june
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB29047/70A
Inventor
Tiberio Bruzzese
Giuseppe Ghielmetti
Rodolfo Ferrari
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Prodotti Antibiotici SpA
Original Assignee
Prodotti Antibiotici SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prodotti Antibiotici SpA filed Critical Prodotti Antibiotici SpA
Priority to GB29047/70A priority Critical patent/GB1292472A/en
Priority to AR230041A priority patent/AR195364A1/en
Priority to LU63315D priority patent/LU63315A1/xx
Priority to BE768361A priority patent/BE768361A/en
Priority to FR7121243A priority patent/FR2100763B1/fr
Priority to DE2129422A priority patent/DE2129422C3/en
Publication of GB1292472A publication Critical patent/GB1292472A/en
Priority to US360942A priority patent/US3901912A/en
Priority to US360941A priority patent/US3873551A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32Oxygen atoms
    • C07D209/34Oxygen atoms in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/08Esters of oxyacids of phosphorus
    • C07F9/09Esters of phosphoric acids
    • C07F9/12Esters of phosphoric acids with hydroxyaryl compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
    • C07F9/40Esters thereof
    • C07F9/4071Esters thereof the ester moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4084Esters with hydroxyaryl compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/572Five-membered rings
    • C07F9/5728Five-membered rings condensed with carbocyclic rings or carbocyclic ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576Six-membered rings
    • C07F9/58Pyridine rings

Abstract

1292472 Esters of diphenols SPA-SOC PRODOTTI ANTIBIOTICI SpA 10 June 1971 [16 June 1970] 29047/70 Headings C2C and C2P Novel compounds (I) (including salts thereof) where R 1 is H or C 1 to C 6 alkyl, R 2 is C 1 to C 6 alkyl or a heterocycle or CR 1 R 2 signifies a saturated or unsaturated carbocyclic or heterocyclic radical, R 3 is a polybasic inorganic acid residue (e.g. derived from sulphuric, phosphoric or sulphurous acid) and R 4 is H, acyl or R 3 with the proviso that R 4 is not sulpho when R 3 is sulpho and CR 1 R 2 signifies isopropylidene, 2-picolylidene or 3-phthalidylidene, are made by esterifying either the corresponding di - hydroxy compounds or the related dihydroxy compounds carrying halo substituent(s) on the benzene rings and which are adjacent to the hydroxy groups, in which case the halogen atom(s) are subsequently removed. Pharmaceutical preparations having laxative action contain (I) as active ingredient; administration may be orally, rectally or parenterally.
GB29047/70A 1970-06-16 1970-06-16 Esters of diphenolic substances Expired GB1292472A (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
GB29047/70A GB1292472A (en) 1970-06-16 1970-06-16 Esters of diphenolic substances
AR230041A AR195364A1 (en) 1970-06-16 1970-07-16 PROCEDURE FOR THE PREPARATION OF NEW PHENOLIC ESTERS OF INORGANIC POLYBASIC ACIDS
LU63315D LU63315A1 (en) 1970-06-16 1971-06-10
BE768361A BE768361A (en) 1970-06-16 1971-06-10 DIPHENOL ESTERS
FR7121243A FR2100763B1 (en) 1970-06-16 1971-06-11
DE2129422A DE2129422C3 (en) 1970-06-16 1971-06-14 4-acetoxy-4'-sulfoxydiphenyl (pyridyl-2) methane
US360942A US3901912A (en) 1970-06-16 1973-05-16 3,3-bis-(p-phosphonoxy- and p-sulphoxy-phenyl)-2-indolinones
US360941A US3873551A (en) 1970-06-16 1973-05-16 4-acetoxy-4{40 -sulfoxydiphenyl-(2-pyridyl)methane and sodium salt thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB29047/70A GB1292472A (en) 1970-06-16 1970-06-16 Esters of diphenolic substances

Publications (1)

Publication Number Publication Date
GB1292472A true GB1292472A (en) 1972-10-11

Family

ID=10285361

Family Applications (1)

Application Number Title Priority Date Filing Date
GB29047/70A Expired GB1292472A (en) 1970-06-16 1970-06-16 Esters of diphenolic substances

Country Status (6)

Country Link
AR (1) AR195364A1 (en)
BE (1) BE768361A (en)
DE (1) DE2129422C3 (en)
FR (1) FR2100763B1 (en)
GB (1) GB1292472A (en)
LU (1) LU63315A1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4053483A (en) * 1974-05-18 1977-10-11 Doctor Andreu S.A. Derivatives of 3,3-bis-(4-hydroxyphenyl)-2-indolinone and process for the preparation thereof
WO2008071387A1 (en) * 2006-12-11 2008-06-19 Topotarget A/S Prodrugs of diphenyl ox- indol- 2 -one compounds for the treatment of cancers

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2764590A (en) * 1952-03-17 1956-09-25 Thomae Gmbh Dr K Certain 4, 4'-disubstituted-diphenylpyridyl methanes and process

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4053483A (en) * 1974-05-18 1977-10-11 Doctor Andreu S.A. Derivatives of 3,3-bis-(4-hydroxyphenyl)-2-indolinone and process for the preparation thereof
WO2008071387A1 (en) * 2006-12-11 2008-06-19 Topotarget A/S Prodrugs of diphenyl ox- indol- 2 -one compounds for the treatment of cancers

Also Published As

Publication number Publication date
FR2100763A1 (en) 1972-03-24
LU63315A1 (en) 1971-09-13
BE768361A (en) 1971-11-03
AR195364A1 (en) 1973-10-08
DE2129422A1 (en) 1972-02-03
DE2129422B2 (en) 1976-12-30
DE2129422C3 (en) 1980-02-21
FR2100763B1 (en) 1977-01-14

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Legal Events

Date Code Title Description
PS Patent sealed
429A Application made for amendment of specification (sect. 29/1949)
429H Application (made) for amendment of specification now open to opposition (sect. 29/1949)
429D Case decided by the comptroller ** specification amended (sect. 29/1949)
PCNP Patent ceased through non-payment of renewal fee