ES424751A1 - Procedimiento para la preparacion de compuestos triciclos derivados de dibenzo (b,f) tiepina. - Google Patents
Procedimiento para la preparacion de compuestos triciclos derivados de dibenzo (b,f) tiepina.Info
- Publication number
- ES424751A1 ES424751A1 ES424751A ES424751A ES424751A1 ES 424751 A1 ES424751 A1 ES 424751A1 ES 424751 A ES424751 A ES 424751A ES 424751 A ES424751 A ES 424751A ES 424751 A1 ES424751 A1 ES 424751A1
- Authority
- ES
- Spain
- Prior art keywords
- dibenzo
- preparation
- see formula
- general formula
- thiepins
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title 1
- 125000004193 piperazinyl group Chemical group 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- KMAWVRYYKYVCNR-UHFFFAOYSA-N benzo[b][1]benzothiepine Chemical class C1=CC2=CC=CC=C2SC2=CC=CC=C21 KMAWVRYYKYVCNR-UHFFFAOYSA-N 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 125000001841 imino group Chemical group [H]N=* 0.000 abstract 1
- -1 methoxy, methylthio, dimethylsulfamoyl Chemical group 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
- 125000004434 sulfur atom Chemical group 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
- C07D337/02—Seven-membered rings
- C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D337/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D337/14—[b,f]-condensed
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH460573A CH593970A5 (en) | 1973-03-30 | 1973-03-30 | 10-(4-Substd. piperazino) dibenzo (b,f) thiepins - CNS depressants without cataleptic side-effects |
| CH44874 | 1974-01-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES424751A1 true ES424751A1 (es) | 1977-01-01 |
Family
ID=25684603
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES424751A Expired ES424751A1 (es) | 1973-03-30 | 1974-03-29 | Procedimiento para la preparacion de compuestos triciclos derivados de dibenzo (b,f) tiepina. |
| ES447120A Expired ES447120A1 (es) | 1973-03-30 | 1976-04-17 | Procedimiento para la preparacion de derivado de dibenzo (b,f) tiepina. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES447120A Expired ES447120A1 (es) | 1973-03-30 | 1976-04-17 | Procedimiento para la preparacion de derivado de dibenzo (b,f) tiepina. |
Country Status (16)
| Country | Link |
|---|---|
| JP (1) | JPS49135982A (en, 2012) |
| AR (1) | AR218600A1 (en, 2012) |
| AT (1) | AT344177B (en, 2012) |
| CA (1) | CA1024516A (en, 2012) |
| DD (1) | DD113545A5 (en, 2012) |
| DE (1) | DE2412522A1 (en, 2012) |
| ES (2) | ES424751A1 (en, 2012) |
| FR (1) | FR2223027B1 (en, 2012) |
| GB (1) | GB1464977A (en, 2012) |
| HU (1) | HU168402B (en, 2012) |
| IE (1) | IE39099B1 (en, 2012) |
| IL (1) | IL44427A (en, 2012) |
| LU (1) | LU69734A1 (en, 2012) |
| NL (1) | NL7404312A (en, 2012) |
| PH (1) | PH12737A (en, 2012) |
| PL (1) | PL96534B1 (en, 2012) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH611898A5 (en, 2012) * | 1975-06-06 | 1979-06-29 | Hoffmann La Roche | |
| CS249455B1 (en) * | 1985-01-24 | 1987-03-12 | Miroslav Protiva | N-substituted 2-chloro-7-fluoro-10-piperazino-10,11-dihydrodibenzo(b,f)thiepines and their salts and method of their preparation |
| US4792604A (en) * | 1987-03-20 | 1988-12-20 | Gaf Corporation | Manufacture of haloalkyl lactams |
| AU717431B2 (en) * | 1996-07-01 | 2000-03-23 | Schering Corporation | Muscarinic antagonists |
| US5935958A (en) * | 1996-07-01 | 1999-08-10 | Schering Corporation | Muscarinic antagonists |
| SE0301010D0 (sv) | 2003-04-07 | 2003-04-07 | Astrazeneca Ab | Novel compounds |
| SA04250253B1 (ar) | 2003-08-21 | 2009-11-10 | استرازينيكا ايه بي | احماض فينوكسي اسيتيك مستبدلة باعتبارها مركبات صيدلانية لعلاج الامراض التنفسية مثل الربو ومرض الانسداد الرئوي المزمن |
| GB0415320D0 (en) * | 2004-07-08 | 2004-08-11 | Astrazeneca Ab | Novel compounds |
| GB0418830D0 (en) | 2004-08-24 | 2004-09-22 | Astrazeneca Ab | Novel compounds |
| DK1817282T3 (da) | 2004-11-23 | 2011-10-10 | Astrazeneca Ab | Til behandling af respiratoriske sygdomme egnede phenoxy derivater |
| WO2007039736A1 (en) | 2005-10-06 | 2007-04-12 | Astrazeneca Ab | Novel compounds |
| TW200745003A (en) | 2005-10-06 | 2007-12-16 | Astrazeneca Ab | Novel compounds |
| UA100983C2 (ru) | 2007-07-05 | 2013-02-25 | Астразенека Аб | Бифенилоксипропановая кислота как модулятор crth2 и интермедиаты |
-
1974
- 1974-03-08 DD DD177070A patent/DD113545A5/xx unknown
- 1974-03-15 DE DE2412522A patent/DE2412522A1/de not_active Withdrawn
- 1974-03-15 IL IL44427A patent/IL44427A/xx unknown
- 1974-03-25 IE IE644/74A patent/IE39099B1/xx unknown
- 1974-03-27 FR FR7410498A patent/FR2223027B1/fr not_active Expired
- 1974-03-28 JP JP49034054A patent/JPS49135982A/ja active Pending
- 1974-03-28 LU LU69734*A patent/LU69734A1/xx unknown
- 1974-03-28 PH PH15666A patent/PH12737A/en unknown
- 1974-03-29 NL NL7404312A patent/NL7404312A/xx unknown
- 1974-03-29 GB GB1401874A patent/GB1464977A/en not_active Expired
- 1974-03-29 ES ES424751A patent/ES424751A1/es not_active Expired
- 1974-03-29 CA CA196,354A patent/CA1024516A/en not_active Expired
- 1974-03-29 AT AT260074A patent/AT344177B/de not_active IP Right Cessation
- 1974-03-29 HU HUHO1661A patent/HU168402B/hu unknown
- 1974-03-29 PL PL1974182109A patent/PL96534B1/pl unknown
- 1974-11-05 AR AR256397A patent/AR218600A1/es active
-
1976
- 1976-04-17 ES ES447120A patent/ES447120A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DD113545A5 (en, 2012) | 1975-06-12 |
| AR218600A1 (es) | 1980-06-30 |
| ES447120A1 (es) | 1977-09-16 |
| AT344177B (de) | 1978-07-10 |
| GB1464977A (en) | 1977-02-16 |
| DE2412522A1 (de) | 1974-10-10 |
| PL96534B1 (pl) | 1977-12-31 |
| FR2223027A1 (en, 2012) | 1974-10-25 |
| IL44427A0 (en) | 1974-06-30 |
| IL44427A (en) | 1978-06-15 |
| NL7404312A (en, 2012) | 1974-10-02 |
| IE39099B1 (en) | 1978-08-02 |
| FR2223027B1 (en, 2012) | 1977-05-06 |
| HU168402B (en, 2012) | 1976-04-28 |
| CA1024516A (en) | 1978-01-17 |
| JPS49135982A (en, 2012) | 1974-12-27 |
| AU6582774A (en) | 1975-08-21 |
| IE39099L (en) | 1974-09-30 |
| LU69734A1 (en, 2012) | 1976-02-04 |
| ATA260074A (de) | 1977-11-15 |
| PH12737A (en) | 1979-08-09 |
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