ES422738A1 - Procedimiento para la obtencion de compuestos heterocicli- cos a base de piperazina u homopiperazina n-aciladas. - Google Patents
Procedimiento para la obtencion de compuestos heterocicli- cos a base de piperazina u homopiperazina n-aciladas.Info
- Publication number
- ES422738A1 ES422738A1 ES422738A ES422738A ES422738A1 ES 422738 A1 ES422738 A1 ES 422738A1 ES 422738 A ES422738 A ES 422738A ES 422738 A ES422738 A ES 422738A ES 422738 A1 ES422738 A1 ES 422738A1
- Authority
- ES
- Spain
- Prior art keywords
- group
- general formula
- acylated
- derivative
- piperazine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000004050 homopiperazines Chemical class 0.000 title abstract 4
- 150000004885 piperazines Chemical class 0.000 title abstract 4
- GLUUGHFHXGJENI-UHFFFAOYSA-N diethylenediamine Natural products C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 5
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 125000005843 halogen group Chemical group 0.000 abstract 4
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 1
- 125000001494 2-propynyl group Chemical group [H]C#CC([H])([H])* 0.000 abstract 1
- 230000006181 N-acylation Effects 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000000816 ethylene group Chemical group [H]C([H])([*:1])C([H])([H])[*:2] 0.000 abstract 1
- 125000000219 ethylidene group Chemical group [H]C(=[*])C([H])([H])[H] 0.000 abstract 1
- 150000002391 heterocyclic compounds Chemical class 0.000 abstract 1
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000001453 quaternary ammonium group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2304155A DE2304155A1 (de) | 1973-01-29 | 1973-01-29 | N-acylierte substituierte piperazinbzw. homopiperazinderivate, sowie verfahren zu ihrer herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES422738A1 true ES422738A1 (es) | 1976-08-01 |
Family
ID=5870202
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES422738A Expired ES422738A1 (es) | 1973-01-29 | 1974-01-29 | Procedimiento para la obtencion de compuestos heterocicli- cos a base de piperazina u homopiperazina n-aciladas. |
Country Status (7)
| Country | Link |
|---|---|
| JP (1) | JPS505389A (enrdf_load_stackoverflow) |
| BE (1) | BE810293A (enrdf_load_stackoverflow) |
| DE (1) | DE2304155A1 (enrdf_load_stackoverflow) |
| ES (1) | ES422738A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2215236B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1434323A (enrdf_load_stackoverflow) |
| NL (1) | NL7401215A (enrdf_load_stackoverflow) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4180574A (en) * | 1978-12-26 | 1979-12-25 | Abbott Laboratories | Certain ovicidal piperazines |
| JPS5879986A (ja) * | 1981-11-06 | 1983-05-13 | Otsuka Pharmaceut Co Ltd | アニリン誘導体 |
| US4585774A (en) * | 1981-05-08 | 1986-04-29 | Otsuka Pharmaceutical Co., Ltd. | Aniline derivatives and cardiotonic composition |
| US6207665B1 (en) * | 1997-06-12 | 2001-03-27 | Schering Aktiengesellschaft | Piperazine derivatives and their use as anti-inflammatory agents |
| WO2001062749A1 (en) * | 2000-02-22 | 2001-08-30 | Cv Therapeutics, Inc. | Substituted piperazine compounds |
| DE60234453D1 (de) * | 2001-07-02 | 2009-12-31 | High Point Pharmaceuticals Llc | Substituierte piperazin- und diazepanderivate zur verwendung als histamin h3 rezeptormodulatoren |
| US7208497B2 (en) | 2001-07-02 | 2007-04-24 | Novo Nordisk A/S | Substituted piperazines and diazepanes |
| US20090197891A1 (en) * | 2004-04-15 | 2009-08-06 | Laurent Lecanu | Use of (4-Alkylpiperazinyl)(phenyl) methanones in the treatment of alzheimer's disease |
| JP2008007443A (ja) * | 2006-06-28 | 2008-01-17 | Shiseido Co Ltd | 桂皮酸誘導体、その紫外線吸収剤としての用途、及びこれを配合した紫外線吸収性組成物、皮膚外用剤。 |
| WO2009031202A1 (ja) * | 2007-09-04 | 2009-03-12 | Shiseido Company Ltd. | 桂皮酸誘導体及びその紫外線吸収剤としての利用 |
| CN102656151A (zh) * | 2009-09-04 | 2012-09-05 | 扎里卡斯药品有限公司 | 治疗疼痛和癫痫的取代的杂环衍生物 |
| WO2014134306A1 (en) | 2013-03-01 | 2014-09-04 | Zalicus Pharmaceuticals, Ltd. | Heterocyclic inhibitors of the sodium channel |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE774447A (fr) * | 1970-11-11 | 1972-02-14 | Biasedra Lab | Nouveaux derives de la salicylamide et leur application en therapeutique |
-
1973
- 1973-01-29 DE DE2304155A patent/DE2304155A1/de active Pending
-
1974
- 1974-01-28 GB GB378474A patent/GB1434323A/en not_active Expired
- 1974-01-29 ES ES422738A patent/ES422738A1/es not_active Expired
- 1974-01-29 BE BE140287A patent/BE810293A/xx unknown
- 1974-01-29 NL NL7401215A patent/NL7401215A/xx unknown
- 1974-01-29 FR FR7402849A patent/FR2215236B1/fr not_active Expired
- 1974-01-29 JP JP49012644A patent/JPS505389A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| FR2215236B1 (enrdf_load_stackoverflow) | 1977-11-04 |
| NL7401215A (enrdf_load_stackoverflow) | 1974-07-31 |
| JPS505389A (enrdf_load_stackoverflow) | 1975-01-21 |
| DE2304155A1 (de) | 1974-08-01 |
| BE810293A (fr) | 1974-05-16 |
| FR2215236A1 (enrdf_load_stackoverflow) | 1974-08-23 |
| GB1434323A (en) | 1976-05-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB1047935A (en) | Substituted piperazines and preparation thereof | |
| ES467288A1 (es) | Un procedimiento para la preparacion de nuevas n-(aminoal- cohil sustituido)-2-oxo-1-pirrolidinacetamidas. | |
| ES422738A1 (es) | Procedimiento para la obtencion de compuestos heterocicli- cos a base de piperazina u homopiperazina n-aciladas. | |
| GB1120463A (en) | Derivatives of 1,3-diazafluoranthene-1-oxide | |
| ES387016A1 (es) | Un procedimiento para la preparacion de derivado de isoqui-nolina. | |
| ES405942A1 (es) | Procedimiento para la preparacion de 2-fenilimino-imidazo- lidinas. | |
| ES331339A1 (es) | Procedimiento para la preparacion de alquilenpiperidinas sustituidas. | |
| ES391633A1 (es) | Un procedimiento para la preparacion de una 2,2-diaril-4- piperidinobutiramida. | |
| ES385627A2 (es) | Procedimiento para la preparacion de derivados de morfoli- na. | |
| ES428400A1 (es) | Procedimiento para la preparacion de nuevos fenolaldehidos. | |
| ES423058A1 (es) | Procedimiento de preparacion de nuevos deivados de la i- soindolina. | |
| ES390163A1 (es) | Procedimiento para la preparacion de amino-derivados de los acidos pirazolo (3,4-b) piridina-5-carboxilicos. | |
| ES417700A1 (es) | Procedimiento para la preparacion de benceno-1,3-disulfona-midas sustituidas con radicales basicos. | |
| ES393934A2 (es) | Procedimiento para la preparacion de derivados de teofili- na. | |
| ES419019A1 (es) | Procedimiento para la preparacion de compuestos polici- clicos. | |
| ES422737A1 (es) | Procedimiento para la obtencion de compuestos heterocicli- cos a base de piperazina u homopiperazina. | |
| ES401342A1 (es) | Procedimiento para la preparacion de nuevos derivados de lapiridina y de sus sales. | |
| ES301524A1 (es) | Procedimiento de preparación de composiciones antivirus en forma unitaria de dosificación | |
| ES435351A1 (es) | Procedimiento para preparar 1-(3-fenil-propil)-4-furoilpi- perazinas. | |
| ES442710A1 (es) | Un procedimiento para preparar nuevos derivados de piperazi-na. | |
| ES400414A1 (es) | Procedimiento para la preparacion de derivados de piperidi-na n-sustituidos y su utilizacion como estabilizadores. | |
| ES406417A1 (es) | Procedimiento para la preparacion de alcohilteofilinas. | |
| ES398968A1 (es) | Procedimiento para la obtencion de derivados de la 1,2,4 pirimido (4,5-e) tiadicina. | |
| ES360031A1 (es) | Procedimiento para la preparacion de 1,2,4-oxadiazoles iso-meros. | |
| ES412061A1 (es) | Procedimiento para la obtencion de derivados de fenoxipro- pilamina. |