ES422320A1 - Procedimiento para la preparacion de nuevas 1,4-benzodiaze-pinas. - Google Patents
Procedimiento para la preparacion de nuevas 1,4-benzodiaze-pinas.Info
- Publication number
- ES422320A1 ES422320A1 ES422320A ES422320A ES422320A1 ES 422320 A1 ES422320 A1 ES 422320A1 ES 422320 A ES422320 A ES 422320A ES 422320 A ES422320 A ES 422320A ES 422320 A1 ES422320 A1 ES 422320A1
- Authority
- ES
- Spain
- Prior art keywords
- compound
- general formula
- signifies
- procedure
- atom
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 3
- 229940049706 benzodiazepine Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Chemical group BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- -1 pyrrolidino, piperidino Chemical group 0.000 abstract 2
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 2
- GUJAGMICFDYKNR-UHFFFAOYSA-N 1,4-benzodiazepine Chemical class N1C=CN=CC2=CC=CC=C12 GUJAGMICFDYKNR-UHFFFAOYSA-N 0.000 abstract 1
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical group [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 230000001476 alcoholic effect Effects 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 125000000000 cycloalkoxy group Chemical group 0.000 abstract 1
- 125000004981 cycloalkylmethyl group Chemical group 0.000 abstract 1
- 238000006356 dehydrogenation reaction Methods 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052740 iodine Chemical group 0.000 abstract 1
- 125000004573 morpholin-4-yl group Chemical group N1(CCOCC1)* 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- WZCZNEGTXVXAAS-UHFFFAOYSA-N trifluoromethanol Chemical compound OC(F)(F)F WZCZNEGTXVXAAS-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19732326657 DE2326657A1 (de) | 1973-05-25 | 1973-05-25 | Neue verfahren zur herstellung von 1,4-benzodiazepinen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES422320A1 true ES422320A1 (es) | 1976-04-16 |
Family
ID=5882116
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES422320A Expired ES422320A1 (es) | 1973-05-25 | 1974-01-16 | Procedimiento para la preparacion de nuevas 1,4-benzodiaze-pinas. |
| ES422321A Expired ES422321A1 (es) | 1973-05-25 | 1974-01-16 | Procedimiento para la preparacion de nuevas 1-4benzodiaze- pinas. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES422321A Expired ES422321A1 (es) | 1973-05-25 | 1974-01-16 | Procedimiento para la preparacion de nuevas 1-4benzodiaze- pinas. |
Country Status (8)
| Country | Link |
|---|---|
| AT (3) | AT327926B (enrdf_load_stackoverflow) |
| BG (2) | BG21407A3 (enrdf_load_stackoverflow) |
| CH (2) | CH590855A5 (enrdf_load_stackoverflow) |
| CS (1) | CS176250B2 (enrdf_load_stackoverflow) |
| DE (1) | DE2326657A1 (enrdf_load_stackoverflow) |
| ES (2) | ES422320A1 (enrdf_load_stackoverflow) |
| PL (2) | PL92134B1 (enrdf_load_stackoverflow) |
| SU (2) | SU572203A3 (enrdf_load_stackoverflow) |
-
1973
- 1973-05-25 DE DE19732326657 patent/DE2326657A1/de active Pending
- 1973-07-09 CH CH1371076A patent/CH590855A5/xx not_active IP Right Cessation
- 1973-07-09 CH CH1370976A patent/CH589633A5/xx not_active IP Right Cessation
- 1973-07-10 BG BG2533673A patent/BG21407A3/xx unknown
- 1973-07-10 BG BG026530A patent/BG21219A3/xx unknown
- 1973-07-11 PL PL17820973A patent/PL92134B1/pl unknown
- 1973-07-11 AT AT1008474A patent/AT327926B/de not_active IP Right Cessation
- 1973-07-11 AT AT1008473A patent/ATA1008474A/de unknown
- 1973-07-11 AT AT1008374A patent/AT327925B/de not_active IP Right Cessation
- 1973-07-11 PL PL17820873A patent/PL92133B1/pl unknown
- 1973-07-12 CS CS3273A patent/CS176250B2/cs unknown
-
1974
- 1974-01-16 ES ES422320A patent/ES422320A1/es not_active Expired
- 1974-01-16 ES ES422321A patent/ES422321A1/es not_active Expired
- 1974-10-09 SU SU7402065459A patent/SU572203A3/ru active
- 1974-10-09 SU SU7402067357A patent/SU563916A3/ru active
Also Published As
| Publication number | Publication date |
|---|---|
| SU572203A3 (ru) | 1977-09-05 |
| CH590855A5 (enrdf_load_stackoverflow) | 1977-08-31 |
| CS176250B2 (enrdf_load_stackoverflow) | 1977-06-30 |
| ES422321A1 (es) | 1976-04-16 |
| BG21407A3 (enrdf_load_stackoverflow) | 1976-05-20 |
| AT327925B (de) | 1976-02-25 |
| BG21219A3 (bg) | 1976-03-20 |
| CH589633A5 (enrdf_load_stackoverflow) | 1977-07-15 |
| DE2326657A1 (de) | 1974-12-12 |
| SU563916A3 (ru) | 1977-06-30 |
| ATA1008474A (de) | 1975-05-15 |
| PL92134B1 (enrdf_load_stackoverflow) | 1977-03-31 |
| ATA1008374A (de) | 1975-05-15 |
| AT327926B (de) | 1976-02-25 |
| PL92133B1 (enrdf_load_stackoverflow) | 1977-03-31 |
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