ES421767A2 - Un procedimiento para la preparacion de acidos 5-sulfamil- benzoicos sustituidos en la posicion 2. - Google Patents

Un procedimiento para la preparacion de acidos 5-sulfamil- benzoicos sustituidos en la posicion 2.

Info

Publication number
ES421767A2
ES421767A2 ES421767A ES421767A ES421767A2 ES 421767 A2 ES421767 A2 ES 421767A2 ES 421767 A ES421767 A ES 421767A ES 421767 A ES421767 A ES 421767A ES 421767 A2 ES421767 A2 ES 421767A2
Authority
ES
Spain
Prior art keywords
formula
hydrogen
bromine
chlorine
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES421767A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US00318213A external-priority patent/US3843662A/en
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of ES421767A2 publication Critical patent/ES421767A2/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C07D295/26Sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/30Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/37Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/34Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40Oxygen atoms
    • C07D211/42Oxygen atoms attached in position 3 or 5
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Fodder In General (AREA)
ES421767A 1972-12-26 1973-12-24 Un procedimiento para la preparacion de acidos 5-sulfamil- benzoicos sustituidos en la posicion 2. Expired ES421767A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US00318213A US3843662A (en) 1971-12-09 1972-12-26 2-halo-5-(substituted piperidino sulfonyl)benzoic acids

Publications (1)

Publication Number Publication Date
ES421767A2 true ES421767A2 (es) 1977-07-01

Family

ID=23237158

Family Applications (2)

Application Number Title Priority Date Filing Date
ES421767A Expired ES421767A2 (es) 1972-12-26 1973-12-24 Un procedimiento para la preparacion de acidos 5-sulfamil- benzoicos sustituidos en la posicion 2.
ES74425208A Expired ES425208A1 (es) 1972-12-26 1974-04-10 Procedimiento para la preparacion de acidos 5-sulfamilben- zoicos sustituidos en la posicion 2.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES74425208A Expired ES425208A1 (es) 1972-12-26 1974-04-10 Procedimiento para la preparacion de acidos 5-sulfamilben- zoicos sustituidos en la posicion 2.

Country Status (11)

Country Link
JP (2) JPS4986522A (de)
AR (1) AR214849A1 (de)
AU (1) AU6366973A (de)
BE (1) BE808939R (de)
CA (1) CA1012974A (de)
DE (1) DE2363786A1 (de)
ES (2) ES421767A2 (de)
FR (1) FR2211261B2 (de)
GB (1) GB1458029A (de)
NL (1) NL7317455A (de)
ZA (1) ZA739662B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1983000013A1 (en) * 1980-11-10 1983-01-06 Mochida Pharm Co Ltd Medicinal composition having an antiviral effect
AU539797B2 (en) * 1981-06-22 1984-10-18 Hodogaya Chemical Co. Ltd. Aminosulfonyl benzoic acid derivatives
AU533742B2 (en) * 1981-06-22 1983-12-08 Mochida Pharmaceutical Co., Ltd. Antiviral compositions
DE3732374A1 (de) * 1987-09-25 1989-04-06 Basf Lacke & Farben Zink-, blei- und/oder calciumsalze von carbonsaeuren und deren verwendung als korrosionsschutzmittel
DE19941540C2 (de) * 1999-09-01 2002-08-29 Aventis Pharma Gmbh Sulfonylcarboxamide zur Herstellung von Medikamenten zur Prophylaxe oder Behandlung von Hyperlipidämie

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1122541B (de) * 1959-12-28 1962-01-25 Hoechst Ag Verfahren zur Herstellung von Sulfamyl-anthranilsaeuren
FR1472906A (fr) * 1961-05-08 1967-03-17 Parke Davis & Co Esters d'acides 4-halo-3-sulfamoylbenzoïques et leur procédé de production
FR1450358A (fr) * 1960-09-03 1966-06-24 Parke Davis & Co Production de 4-halogéno-3-sulfamylbenzamides nouvelles
FR1311859A (fr) * 1961-09-18 1962-12-14 Soc Ind Fab Antibiotiques Sifa Nouveaux dérivés des sulfamides, et procédé de préparation
US3565920A (en) * 1966-12-29 1971-02-23 Ciba Geigy Corp 5-sulfamyl-anthranilic acids
US3567746A (en) * 1968-07-10 1971-03-02 Pennwalt Corp N-aryl benzamides
US3700773A (en) * 1969-06-25 1972-10-24 Merck & Co Inc Substituted phenylsulfamyl salicyclic acids and derivatives thereof in the treatment of inflammation

Also Published As

Publication number Publication date
JPS5924975B2 (ja) 1984-06-13
ZA739662B (en) 1975-01-29
FR2211261B2 (de) 1977-04-15
FR2211261A2 (de) 1974-07-19
GB1458029A (en) 1976-12-08
JPS4986522A (de) 1974-08-19
AU6366973A (en) 1975-06-19
DE2363786A1 (de) 1974-07-11
AR214849A1 (es) 1979-08-15
JPS58170756A (ja) 1983-10-07
ES425208A1 (es) 1976-06-16
CA1012974A (en) 1977-06-28
BE808939R (fr) 1974-06-21
NL7317455A (de) 1974-06-28

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