ES408603A1 - 10-piperazinyl-dibenzo-b,f thiepins methods for their preparation and compositions containing them - Google Patents

10-piperazinyl-dibenzo-b,f thiepins methods for their preparation and compositions containing them

Info

Publication number
ES408603A1
ES408603A1 ES408603A ES408603A ES408603A1 ES 408603 A1 ES408603 A1 ES 408603A1 ES 408603 A ES408603 A ES 408603A ES 408603 A ES408603 A ES 408603A ES 408603 A1 ES408603 A1 ES 408603A1
Authority
ES
Spain
Prior art keywords
lower alkyl
preparation
formula
thiepins
dibenzo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES408603A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES408603A1 publication Critical patent/ES408603A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
    • C07D337/02—Seven-membered rings
    • C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D337/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D337/14—[b,f]-condensed

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)

Abstract

Procedure for the preparation of tricyclic compounds of the formula **(See formula)** in which R is hydrogen, cyano, nitro, halogen, lower alkyl, or lower alkoxy; R1 is hydrogen, cyano, carboxyl, nitro, halogen, lower alkyl, lower alkoxy lower alkylthio, lower alkylsulfinyl or amino-lower alkyl, R2 is phenyl, benzyl or lower alkyl, and its pharmaceutically acceptable acid addition salts, characterized in that it is a compound of the formula **(See formula)** in which R and R2 have the same meaning that has been attributed to them before, while R1'is like R1, but does not represent lower alkylsulfinyl, with an oxidizing agent and, if desired, converting a resulting base to a pharmaceutically acceptable acid addition salt. (Machine-translation by Google Translate, not legally binding)
ES408603A 1971-11-16 1972-11-15 10-piperazinyl-dibenzo-b,f thiepins methods for their preparation and compositions containing them Expired ES408603A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US19933371A 1971-11-16 1971-11-16

Publications (1)

Publication Number Publication Date
ES408603A1 true ES408603A1 (en) 1975-10-01

Family

ID=22737104

Family Applications (2)

Application Number Title Priority Date Filing Date
ES408603A Expired ES408603A1 (en) 1971-11-16 1972-11-15 10-piperazinyl-dibenzo-b,f thiepins methods for their preparation and compositions containing them
ES418811A Expired ES418811A1 (en) 1971-11-16 1973-09-17 10-piperazinyl-dibenzo-b,f thiepins methods for their preparation and compositions containing them

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES418811A Expired ES418811A1 (en) 1971-11-16 1973-09-17 10-piperazinyl-dibenzo-b,f thiepins methods for their preparation and compositions containing them

Country Status (12)

Country Link
JP (1) JPS4861490A (en)
AU (1) AU4891472A (en)
BE (1) BE791348A (en)
DE (1) DE2252806A1 (en)
ES (2) ES408603A1 (en)
FR (1) FR2160541B1 (en)
GB (1) GB1369525A (en)
HU (1) HU166241B (en)
IE (1) IE36841B1 (en)
IL (1) IL40828A0 (en)
NL (1) NL7213809A (en)
ZA (1) ZA726537B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL62705A (en) * 1980-04-25 1986-04-29 Sparamedica Ag Topical anti-inflammatory pharmaceutical compositions containing piperazine derivatives
EP0101234B1 (en) * 1982-08-06 1986-10-29 The Boots Company PLC Therapeutic agent
JPH0655714B2 (en) * 1985-05-09 1994-07-27 藤沢薬品工業株式会社 Process for producing diphenylthioether derivative
US6423708B1 (en) * 1996-09-30 2002-07-23 Pfizer Inc Aralkyl and aralkylidene heterocyclic lactams and imides

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH539044A (en) * 1967-10-06 1973-08-31 Gnii Orch Poluproduktov I Kras Process for the preparation of quaternary ammonium salts of 1,3-bis (aminomethyl) imidazolidones

Also Published As

Publication number Publication date
FR2160541B1 (en) 1975-10-31
GB1369525A (en) 1974-10-09
JPS4861490A (en) 1973-08-28
BE791348A (en) 1973-05-14
IL40828A0 (en) 1973-01-30
HU166241B (en) 1975-02-28
FR2160541A1 (en) 1973-06-29
ES418811A1 (en) 1976-03-16
NL7213809A (en) 1973-05-18
IE36841B1 (en) 1977-03-02
DE2252806A1 (en) 1973-05-24
IE36841L (en) 1973-05-16
AU4891472A (en) 1974-05-16
ZA726537B (en) 1973-06-27

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