ES406527A1 - Biphenylyl-butyric acid derivs. - anti phlogistics - Google Patents
Biphenylyl-butyric acid derivs. - anti phlogisticsInfo
- Publication number
- ES406527A1 ES406527A1 ES406527A ES406527A ES406527A1 ES 406527 A1 ES406527 A1 ES 406527A1 ES 406527 A ES406527 A ES 406527A ES 406527 A ES406527 A ES 406527A ES 406527 A1 ES406527 A1 ES 406527A1
- Authority
- ES
- Spain
- Prior art keywords
- phlogistics
- biphenylyl
- butyric acid
- choh
- hal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
- C07C205/56—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups bound to carbon atoms of six-membered aromatic rings and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
- C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
- C07C59/56—Unsaturated compounds containing hydroxy or O-metal groups containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/88—Unsaturated compounds containing keto groups containing halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Title cpds. of formula (I): where A = CH2, CHOH or CO R1 = H or hal, or (if R2 and R3 = H) ME R3 = H) Me R2 = H, hal, CN, NO2, NH2, or (1-4C) NH acyl R3 = H or hal R4 = (1-4C) alkyl and at least one of R1-R3 = H, including salts, esters, and lactones of (I), are of use as anti-phlogistics. (I) are prepd. e.g., A = CO, by condensing a biphenyl with a succinic halide or anhydride and a Lewis acid A = CH2 by reducing I (A = CO or CHOH) and other unsatd. analogues A = CHOH by selective, partial redn. of I(A = CO).
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19712112716 DE2112716A1 (en) | 1971-03-17 | 1971-03-17 | Biphenylyl-butyric acid derivs. - anti phlogistics |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES406527A1 true ES406527A1 (en) | 1975-09-01 |
Family
ID=5801760
Family Applications (15)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES400791A Expired ES400791A1 (en) | 1971-03-17 | 1972-03-15 | Biphenylyl-butyric acid derivs. - anti phlogistics |
| ES406528A Expired ES406528A1 (en) | 1971-03-17 | 1972-09-05 | Biphenylyl-butyric acid derivs. - anti phlogistics |
| ES406537A Expired ES406537A1 (en) | 1971-03-17 | 1972-09-09 | Biphenylyl-butyric acid derivs. - anti phlogistics |
| ES406526A Expired ES406526A1 (en) | 1971-03-17 | 1972-09-09 | Biphenylyl-butyric acid derivs. - anti phlogistics |
| ES406538A Expired ES406538A1 (en) | 1971-03-17 | 1972-09-09 | Biphenylyl-butyric acid derivs. - anti phlogistics |
| ES406535A Expired ES406535A1 (en) | 1971-03-17 | 1972-09-09 | Biphenylyl-butyric acid derivs. - anti phlogistics |
| ES406534A Expired ES406534A1 (en) | 1971-03-17 | 1972-09-09 | Biphenylyl-butyric acid derivs. - anti phlogistics |
| ES406539A Expired ES406539A1 (en) | 1971-03-17 | 1972-09-09 | Biphenylyl-butyric acid derivs. - anti phlogistics |
| ES406533A Expired ES406533A1 (en) | 1971-03-17 | 1972-09-09 | Biphenylyl-butyric acid derivs. - anti phlogistics |
| ES406536A Expired ES406536A1 (en) | 1971-03-17 | 1972-09-09 | Biphenylyl-butyric acid derivs. - anti phlogistics |
| ES406529A Expired ES406529A1 (en) | 1971-03-17 | 1972-09-09 | Biphenylyl-butyric acid derivs. - anti phlogistics |
| ES406530A Expired ES406530A1 (en) | 1971-03-17 | 1972-09-09 | Biphenylyl-butyric acid derivs. - anti phlogistics |
| ES406531A Expired ES406531A1 (en) | 1971-03-17 | 1972-09-09 | Biphenylyl-butyric acid derivs. - anti phlogistics |
| ES406527A Expired ES406527A1 (en) | 1971-03-17 | 1972-09-09 | Biphenylyl-butyric acid derivs. - anti phlogistics |
| ES406532A Expired ES406532A1 (en) | 1971-03-17 | 1972-09-09 | Biphenylyl-butyric acid derivs. - anti phlogistics |
Family Applications Before (13)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES400791A Expired ES400791A1 (en) | 1971-03-17 | 1972-03-15 | Biphenylyl-butyric acid derivs. - anti phlogistics |
| ES406528A Expired ES406528A1 (en) | 1971-03-17 | 1972-09-05 | Biphenylyl-butyric acid derivs. - anti phlogistics |
| ES406537A Expired ES406537A1 (en) | 1971-03-17 | 1972-09-09 | Biphenylyl-butyric acid derivs. - anti phlogistics |
| ES406526A Expired ES406526A1 (en) | 1971-03-17 | 1972-09-09 | Biphenylyl-butyric acid derivs. - anti phlogistics |
| ES406538A Expired ES406538A1 (en) | 1971-03-17 | 1972-09-09 | Biphenylyl-butyric acid derivs. - anti phlogistics |
| ES406535A Expired ES406535A1 (en) | 1971-03-17 | 1972-09-09 | Biphenylyl-butyric acid derivs. - anti phlogistics |
| ES406534A Expired ES406534A1 (en) | 1971-03-17 | 1972-09-09 | Biphenylyl-butyric acid derivs. - anti phlogistics |
| ES406539A Expired ES406539A1 (en) | 1971-03-17 | 1972-09-09 | Biphenylyl-butyric acid derivs. - anti phlogistics |
| ES406533A Expired ES406533A1 (en) | 1971-03-17 | 1972-09-09 | Biphenylyl-butyric acid derivs. - anti phlogistics |
| ES406536A Expired ES406536A1 (en) | 1971-03-17 | 1972-09-09 | Biphenylyl-butyric acid derivs. - anti phlogistics |
| ES406529A Expired ES406529A1 (en) | 1971-03-17 | 1972-09-09 | Biphenylyl-butyric acid derivs. - anti phlogistics |
| ES406530A Expired ES406530A1 (en) | 1971-03-17 | 1972-09-09 | Biphenylyl-butyric acid derivs. - anti phlogistics |
| ES406531A Expired ES406531A1 (en) | 1971-03-17 | 1972-09-09 | Biphenylyl-butyric acid derivs. - anti phlogistics |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES406532A Expired ES406532A1 (en) | 1971-03-17 | 1972-09-09 | Biphenylyl-butyric acid derivs. - anti phlogistics |
Country Status (7)
| Country | Link |
|---|---|
| AT (19) | AT311949B (en) |
| CH (2) | CH573387A5 (en) |
| DE (1) | DE2112716A1 (en) |
| DK (1) | DK132944C (en) |
| ES (15) | ES400791A1 (en) |
| SE (1) | SE393102B (en) |
| ZA (1) | ZA721798B (en) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2108500B (en) * | 1981-10-22 | 1985-05-15 | Roussel Uclaf | Aminobenzene medicaments |
| CS243570B1 (en) * | 1984-08-31 | 1986-06-12 | Miroslav Kuchar | Omega-aryloxoalkane acids |
| US5968795A (en) * | 1996-05-15 | 1999-10-19 | Bayer Corporation | Biaryl acetylenes as inhibitors of matrix metalloproteases |
| HRP970243B1 (en) * | 1996-05-15 | 2002-06-30 | Bayer Ag | Inhibition of matrix metalloproteases by substituted phenethyl compounds |
| HRP970245B1 (en) * | 1996-05-15 | 2002-06-30 | Bayer Ag | Biaryl acetilenes as matrix metalloprotease inhibitors |
| EP1244609B1 (en) * | 2000-01-04 | 2003-10-29 | Korea Research Institute Of Chemical Technology | Preparing method of 2-phenylalkanoic acid derivatives |
| FR2817256B1 (en) * | 2000-11-27 | 2005-07-15 | Univ Pasteur | DERIVATIVES OF 4-HYDROXYBUTANOIC ACID AND ITS SUPERIOR APPROACHES AS GAMMA-HYDROXYBUTYRATE (GHB) RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND PHARMACEUTICAL USES |
| AR044152A1 (en) | 2003-05-09 | 2005-08-24 | Bayer Corp | RENTAL DERIVATIVES, METHOD OF PREPARATION AND USE FOR THE TREATMENT OF OBESITY |
| DE102006031813B4 (en) | 2006-07-07 | 2011-04-28 | Christian-Albrechts-Universität Zu Kiel | Use of basic acetophenones as inhibitors of NO synthases |
| MA58653B1 (en) * | 2020-06-26 | 2024-02-29 | Valenta Intellekt Ltd | USE OF A GLUTARIMIDE DERIVATIVE TO TREAT DISEASES RELATED TO ABERRANT INTERLEUKIN-6 ACTIVITY |
-
1971
- 1971-03-17 DE DE19712112716 patent/DE2112716A1/en active Pending
-
1972
- 1972-03-14 CH CH371672A patent/CH573387A5/xx not_active IP Right Cessation
- 1972-03-14 CH CH1317075A patent/CH572015A5/xx not_active IP Right Cessation
- 1972-03-15 ES ES400791A patent/ES400791A1/en not_active Expired
- 1972-03-16 AT AT222272A patent/AT311949B/en not_active IP Right Cessation
- 1972-03-16 AT AT00696/73A patent/AT318594B/en not_active IP Right Cessation
- 1972-03-16 AT AT00680/73A patent/AT319922B/en not_active IP Right Cessation
- 1972-03-16 AT AT00690/73A patent/AT320625B/en not_active IP Right Cessation
- 1972-03-16 AT AT00683/73A patent/AT320624B/en not_active IP Right Cessation
- 1972-03-16 AT AT00684/73A patent/AT318587B/en not_active IP Right Cessation
- 1972-03-16 AT AT00685/73A patent/AT318588B/en active
- 1972-03-16 AT AT00689/73A patent/AT317879B/en active
- 1972-03-16 AT AT00687/73A patent/AT318590B/en not_active IP Right Cessation
- 1972-03-16 SE SE7203420A patent/SE393102B/en unknown
- 1972-03-16 AT AT00688/73A patent/AT319924B/en not_active IP Right Cessation
- 1972-03-16 AT AT00695/73A patent/AT318593B/en not_active IP Right Cessation
- 1972-03-16 AT AT00693/73A patent/AT319925B/en not_active IP Right Cessation
- 1972-03-16 ZA ZA721798A patent/ZA721798B/en unknown
- 1972-03-16 AT AT00681/73A patent/AT320623B/en not_active IP Right Cessation
- 1972-03-16 AT AT00682/73A patent/AT319923B/en not_active IP Right Cessation
- 1972-03-16 AT AT00686/73A patent/AT318589B/en not_active IP Right Cessation
- 1972-03-16 AT AT00694/73A patent/AT318592B/en not_active IP Right Cessation
- 1972-03-16 AT AT00691/73A patent/AT318591B/en not_active IP Right Cessation
- 1972-03-16 AT AT00692/73A patent/AT317880B/en active
- 1972-03-16 DK DK124072A patent/DK132944C/en active
- 1972-03-16 AT AT00697/73A patent/AT318595B/en not_active IP Right Cessation
- 1972-09-05 ES ES406528A patent/ES406528A1/en not_active Expired
- 1972-09-09 ES ES406537A patent/ES406537A1/en not_active Expired
- 1972-09-09 ES ES406526A patent/ES406526A1/en not_active Expired
- 1972-09-09 ES ES406538A patent/ES406538A1/en not_active Expired
- 1972-09-09 ES ES406535A patent/ES406535A1/en not_active Expired
- 1972-09-09 ES ES406534A patent/ES406534A1/en not_active Expired
- 1972-09-09 ES ES406539A patent/ES406539A1/en not_active Expired
- 1972-09-09 ES ES406533A patent/ES406533A1/en not_active Expired
- 1972-09-09 ES ES406536A patent/ES406536A1/en not_active Expired
- 1972-09-09 ES ES406529A patent/ES406529A1/en not_active Expired
- 1972-09-09 ES ES406530A patent/ES406530A1/en not_active Expired
- 1972-09-09 ES ES406531A patent/ES406531A1/en not_active Expired
- 1972-09-09 ES ES406527A patent/ES406527A1/en not_active Expired
- 1972-09-09 ES ES406532A patent/ES406532A1/en not_active Expired
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