ES406433A1 - Un procedimiento para la preparacion de un nuevo producto no toxico de condensacion de dihidroquinoleina-aldehido. - Google Patents
Un procedimiento para la preparacion de un nuevo producto no toxico de condensacion de dihidroquinoleina-aldehido.Info
- Publication number
- ES406433A1 ES406433A1 ES406433A ES406433A ES406433A1 ES 406433 A1 ES406433 A1 ES 406433A1 ES 406433 A ES406433 A ES 406433A ES 406433 A ES406433 A ES 406433A ES 406433 A1 ES406433 A1 ES 406433A1
- Authority
- ES
- Spain
- Prior art keywords
- product
- acid addition
- dihydroquinoline
- reaction mixture
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000005044 dihydroquinolinyl group Chemical class N1(CC=CC2=CC=CC=C12)* 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 4
- 150000003839 salts Chemical class 0.000 abstract 4
- 239000000047 product Substances 0.000 abstract 3
- ZNRLMGFXSPUZNR-UHFFFAOYSA-N 2,2,4-trimethyl-1h-quinoline Chemical compound C1=CC=C2C(C)=CC(C)(C)NC2=C1 ZNRLMGFXSPUZNR-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- 239000011541 reaction mixture Substances 0.000 abstract 2
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 125000003158 alcohol group Chemical group 0.000 abstract 1
- 230000003078 antioxidant effect Effects 0.000 abstract 1
- 239000002585 base Substances 0.000 abstract 1
- 238000009835 boiling Methods 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 239000007859 condensation product Substances 0.000 abstract 1
- 230000006866 deterioration Effects 0.000 abstract 1
- 125000002485 formyl group Chemical class [H]C(*)=O 0.000 abstract 1
- 239000012458 free base Substances 0.000 abstract 1
- 229910001507 metal halide Inorganic materials 0.000 abstract 1
- 150000005309 metal halides Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 230000001590 oxidative effect Effects 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 238000001953 recrystallisation Methods 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/04—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms
- C07D215/06—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms having only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23B—PRESERVATION OF FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES; CHEMICAL RIPENING OF FRUIT OR VEGETABLES
- A23B2/00—Preservation of foods or foodstuffs, in general
- A23B2/70—Preservation of foods or foodstuffs, in general by treatment with chemicals
- A23B2/725—Preservation of foods or foodstuffs, in general by treatment with chemicals in the form of liquids or solids
- A23B2/729—Organic compounds; Microorganisms; Enzymes
- A23B2/771—Organic compounds containing hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
- C11B5/00—Preserving by using additives, e.g. anti-oxidants
- C11B5/0042—Preserving by using additives, e.g. anti-oxidants containing nitrogen
- C11B5/0064—Heterocyclic compounds containing nitrogen in the ring
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Diabetes (AREA)
- Food Science & Technology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Zoology (AREA)
- Obesity (AREA)
- Polymers & Plastics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
- Phenolic Resins Or Amino Resins (AREA)
- Anti-Oxidant Or Stabilizer Compositions (AREA)
- Fodder In General (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HUBA2642A HU162358B (enrdf_load_stackoverflow) | 1971-09-07 | 1971-09-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES406433A1 true ES406433A1 (es) | 1976-01-16 |
Family
ID=10993333
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES406433A Expired ES406433A1 (es) | 1971-09-07 | 1972-09-06 | Un procedimiento para la preparacion de un nuevo producto no toxico de condensacion de dihidroquinoleina-aldehido. |
| ES435497A Expired ES435497A1 (es) | 1971-09-07 | 1975-03-11 | Un procedimiento para la preparacion de un producto farma- ceutico a base de dihidroquinoleina-aldehido. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES435497A Expired ES435497A1 (es) | 1971-09-07 | 1975-03-11 | Un procedimiento para la preparacion de un producto farma- ceutico a base de dihidroquinoleina-aldehido. |
Country Status (22)
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU185208B (en) * | 1979-07-06 | 1984-12-28 | Material Vegyipari Sz | Process for producing the water-soluble derivatives of 6,6-methylene-bis/2,2,4-trimetyl-1,2-dihidric quinoline/ |
| DK328483D0 (da) * | 1983-07-15 | 1983-07-15 | Magius N W Von | Ethoxyquinsalte |
| HU194734B (en) * | 1985-07-11 | 1988-03-28 | Jozsef Bara | Process for production of medical and applicable for human consumption products suitable for treatment and/or prevention of diseases caused by free-radical reactions |
| US4994469A (en) * | 1987-04-22 | 1991-02-19 | Material Vegyipari Kisszovetkezet | Diaclyl-substituted methylene-2,2,4-trimethyl-1,2-dihydroquinolines and a process for the preparation thereof |
| US5202338A (en) * | 1990-10-31 | 1993-04-13 | Vilmos Bar | Dihydroquinoline derivatives, pharmaceutical compositions and methods of use of dihydroquinoline derivatives as modulators of the arachidonic acid cascade |
| EP0497735A1 (de) * | 1991-01-31 | 1992-08-05 | Ciba-Geigy Ag | Hydrochinolinverbindungen |
| CN116239529B (zh) * | 2023-03-21 | 2024-05-24 | 山西大学 | 一种二氧化碳参与的n-甲基四氢喹啉类生物碱的制备方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1906942A (en) * | 1931-09-24 | 1933-05-02 | Naugatuck Chem Co | Treatment of rubber |
-
0
- BE BE788509D patent/BE788509A/xx not_active IP Right Cessation
-
1971
- 1971-09-07 HU HUBA2642A patent/HU162358B/hu not_active IP Right Cessation
-
1972
- 1972-08-22 ZA ZA725777A patent/ZA725777B/xx unknown
- 1972-09-04 AT AT756572A patent/AT319250B/de not_active IP Right Cessation
- 1972-09-04 DD DD165435A patent/DD101667A5/xx unknown
- 1972-09-05 SE SE7211462A patent/SE393982B/xx unknown
- 1972-09-05 BG BG021322A patent/BG19596A3/xx unknown
- 1972-09-05 AU AU46298/72A patent/AU472125B2/en not_active Expired
- 1972-09-06 YU YU02257/72A patent/YU225772A/xx unknown
- 1972-09-06 DE DE2265399A patent/DE2265399C2/de not_active Expired
- 1972-09-06 CH CH1309172A patent/CH580079A5/xx not_active IP Right Cessation
- 1972-09-06 SU SU1827227A patent/SU520045A3/ru active
- 1972-09-06 CA CA151,034A patent/CA992546A/en not_active Expired
- 1972-09-06 DE DE2265400A patent/DE2265400C2/de not_active Expired
- 1972-09-06 GB GB4141372A patent/GB1390991A/en not_active Expired
- 1972-09-06 DK DK440072AA patent/DK135990B/da unknown
- 1972-09-06 CS CS6092A patent/CS170505B2/cs unknown
- 1972-09-06 ES ES406433A patent/ES406433A1/es not_active Expired
- 1972-09-06 DE DE2243777A patent/DE2243777C3/de not_active Expired
- 1972-09-06 FR FR7231617A patent/FR2154469B1/fr not_active Expired
- 1972-09-07 JP JP8996572A patent/JPS5346839B2/ja not_active Expired
- 1972-09-07 NL NLAANVRAGE7212192,A patent/NL174721C/xx not_active IP Right Cessation
- 1972-09-07 RO RO72162A patent/RO60121A2/ro unknown
- 1972-09-07 IT IT28911/72A patent/IT1022011B/it active
-
1975
- 1975-03-11 ES ES435497A patent/ES435497A1/es not_active Expired
- 1975-04-03 SE SE7503840A patent/SE434050B/xx not_active IP Right Cessation
-
1977
- 1977-12-28 JP JP52158728A patent/JPS5940179B2/ja not_active Expired
Also Published As
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