ES406250A1 - A procedure for preparing 2-descarboxi-2- (tetrazol-5-il) prostaglandinas. (Machine-translation by Google Translate, not legally binding) - Google Patents

A procedure for preparing 2-descarboxi-2- (tetrazol-5-il) prostaglandinas. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES406250A1
ES406250A1 ES406250A ES406250A ES406250A1 ES 406250 A1 ES406250 A1 ES 406250A1 ES 406250 A ES406250 A ES 406250A ES 406250 A ES406250 A ES 406250A ES 406250 A1 ES406250 A1 ES 406250A1
Authority
ES
Spain
Prior art keywords
tetrazol
translation
preparing
procedure
machine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES406250A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of ES406250A1 publication Critical patent/ES406250A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D257/00Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04Five-membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/54Quaternary phosphonium compounds
    • C07F9/5407Acyclic saturated phosphonium compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6524Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having four or more nitrogen atoms as the only ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

A procedure for preparing 2-decarboxy-2- [tetrazol-5-yl] prostaglandins of the formula: **(See formula)** where R is selected from the group consisting of (see formula) -alpha-hydroxy and (see formula); R2 and R3 are hydrogen; R1 is selected from the group consisting of hydrogen and lower alkyl; Y is selected from the group consisting of a single bond and a trans double bond; X and Z are each single bonds or are cis double bonds, such that when Z is a cis double bond, X is a cis double bond and Y is a trans double bond; characterized by reacting a compound of formula I above, wherein R, R1, X, Y and Z are as defined above, and R2 and are tetrahydropyranyl, with aqueous acetic acid. (Machine-translation by Google Translate, not legally binding)
ES406250A 1971-09-01 1972-08-31 A procedure for preparing 2-descarboxi-2- (tetrazol-5-il) prostaglandinas. (Machine-translation by Google Translate, not legally binding) Expired ES406250A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17710271A 1971-09-01 1971-09-01

Publications (1)

Publication Number Publication Date
ES406250A1 true ES406250A1 (en) 1976-06-01

Family

ID=22647201

Family Applications (3)

Application Number Title Priority Date Filing Date
ES406250A Expired ES406250A1 (en) 1971-09-01 1972-08-31 A procedure for preparing 2-descarboxi-2- (tetrazol-5-il) prostaglandinas. (Machine-translation by Google Translate, not legally binding)
ES417557A Expired ES417557A1 (en) 1971-09-01 1973-08-03 A procedure for preparing replaced ciclopentan derivatives. (Machine-translation by Google Translate, not legally binding)
ES417558A Expired ES417558A1 (en) 1971-09-01 1973-08-03 A procedure for preparing bromide of 4- (tetrazol-5-il) butiltripenylphosphonium. (Machine-translation by Google Translate, not legally binding)

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES417557A Expired ES417557A1 (en) 1971-09-01 1973-08-03 A procedure for preparing replaced ciclopentan derivatives. (Machine-translation by Google Translate, not legally binding)
ES417558A Expired ES417558A1 (en) 1971-09-01 1973-08-03 A procedure for preparing bromide of 4- (tetrazol-5-il) butiltripenylphosphonium. (Machine-translation by Google Translate, not legally binding)

Country Status (12)

Country Link
JP (1) JPS5724348B2 (en)
AR (4) AR197304A1 (en)
AT (3) ATA51974A (en)
CA (1) CA978939A (en)
DK (1) DK144730C (en)
ES (3) ES406250A1 (en)
FI (1) FI55497C (en)
FR (3) FR2283147A1 (en)
IL (3) IL40183A (en)
PH (3) PH10023A (en)
SE (4) SE409032B (en)
ZA (1) ZA725827B (en)

Also Published As

Publication number Publication date
FR2283136A1 (en) 1976-03-26
SE421526B (en) 1982-01-04
AR199573A1 (en) 1974-09-13
ES417558A1 (en) 1976-06-16
ZA725827B (en) 1973-06-27
FI55497C (en) 1979-08-10
FR2283147A1 (en) 1976-03-26
PH10023A (en) 1976-07-13
SE7606691L (en) 1976-06-11
DK144730B (en) 1982-05-24
SE421525B (en) 1982-01-04
AT335079B (en) 1977-02-25
FR2283134A1 (en) 1976-03-26
IL40183A0 (en) 1972-10-29
JPS4834165A (en) 1973-05-16
FR2283136B1 (en) 1978-05-12
IL48544A (en) 1977-06-30
FR2283134B1 (en) 1978-05-12
AR197304A1 (en) 1974-03-29
JPS5724348B2 (en) 1982-05-24
CA978939A (en) 1975-12-02
AR199784A1 (en) 1974-09-30
SE7606689L (en) 1976-06-11
ES417557A1 (en) 1976-06-16
PH10416A (en) 1977-03-16
AT327219B (en) 1976-01-26
ATA51974A (en) 1975-04-15
FR2283147B1 (en) 1978-05-12
IL48544A0 (en) 1976-01-30
SE409032B (en) 1979-07-23
SE424185B (en) 1982-07-05
SE7606690L (en) 1976-06-11
IL40183A (en) 1977-06-30
DK144730C (en) 1982-10-18
FI55497B (en) 1979-04-30
ATA743472A (en) 1976-06-15
PH10443A (en) 1977-03-25
AR199574A1 (en) 1974-09-13

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