ES404618A1 - Un procedimiento para la preparacion de un ester de acido 3-metil sustituido-7-acilamido-7 metoxi (o hidrogeno)-2-ce- fem-4-carboxilico. - Google Patents
Un procedimiento para la preparacion de un ester de acido 3-metil sustituido-7-acilamido-7 metoxi (o hidrogeno)-2-ce- fem-4-carboxilico.Info
- Publication number
- ES404618A1 ES404618A1 ES404618A ES404618A ES404618A1 ES 404618 A1 ES404618 A1 ES 404618A1 ES 404618 A ES404618 A ES 404618A ES 404618 A ES404618 A ES 404618A ES 404618 A1 ES404618 A1 ES 404618A1
- Authority
- ES
- Spain
- Prior art keywords
- methoxy
- formula
- cephem
- carboxylic acid
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000002148 esters Chemical class 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000002841 Lewis acid Substances 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000005333 aroyloxy group Chemical group 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- 150000007517 lewis acids Chemical class 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- -1 monohydroxyphenyl Chemical group 0.000 abstract 1
- 230000000269 nucleophilic effect Effects 0.000 abstract 1
- 125000001820 oxy group Chemical group [*:1]O[*:2] 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 125000006239 protecting group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/57—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with a further substituent in position 7, e.g. cephamycines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/60—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 3 and 4
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US162703A US3859282A (en) | 1971-07-14 | 1971-07-14 | Process for preparing 3-substituted methyl-7-acylamido-7-methoxy-2-cephem-4-carboxylic acid and its esters |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES404618A1 true ES404618A1 (es) | 1976-04-16 |
Family
ID=22586779
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES404618A Expired ES404618A1 (es) | 1971-07-14 | 1972-07-06 | Un procedimiento para la preparacion de un ester de acido 3-metil sustituido-7-acilamido-7 metoxi (o hidrogeno)-2-ce- fem-4-carboxilico. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US3859282A (en:Method) |
| AT (1) | AT327376B (en:Method) |
| CS (1) | CS167994B2 (en:Method) |
| ES (1) | ES404618A1 (en:Method) |
| PL (1) | PL90346B1 (en:Method) |
| SU (1) | SU589918A3 (en:Method) |
| ZA (1) | ZA724841B (en:Method) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4014873A (en) * | 1973-05-03 | 1977-03-29 | Merck & Co., Inc. | Process for the production of 7-acylamidocephalosporins |
| US4059578A (en) * | 1974-09-09 | 1977-11-22 | Smithkline Corporation | 7-Substituted mercaptoacetamido cephamycins |
| US4053286A (en) * | 1974-09-23 | 1977-10-11 | Merck & Co., Inc. | Process for the preparation of cephalosporin antibiotics |
| US4107432A (en) * | 1975-04-07 | 1978-08-15 | Merck & Co., Inc. | 7-Diacylimido cephalosporins |
| NZ198350A (en) * | 1980-09-25 | 1985-02-28 | Toyama Chemical Co Ltd | Cephalosporins and intermediates;pharmaceutical compositions |
| WO2008103822A1 (en) * | 2007-02-21 | 2008-08-28 | Gh, Llc | Braille embosser |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1208015A (en) * | 1967-03-23 | 1970-10-07 | Glaxo Lab Ltd | Cephalosporins |
-
1971
- 1971-07-11 SU SU711810094A patent/SU589918A3/ru active
- 1971-07-14 US US162703A patent/US3859282A/en not_active Expired - Lifetime
-
1972
- 1972-07-06 ES ES404618A patent/ES404618A1/es not_active Expired
- 1972-07-07 CS CS4829A patent/CS167994B2/cs unknown
- 1972-07-11 AT AT594972A patent/AT327376B/de not_active IP Right Cessation
- 1972-07-13 ZA ZA724841A patent/ZA724841B/xx unknown
- 1972-07-13 PL PL1972156670A patent/PL90346B1/pl unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AT327376B (de) | 1976-01-26 |
| SU589918A3 (ru) | 1978-01-25 |
| ATA594972A (de) | 1975-04-15 |
| CS167994B2 (en:Method) | 1976-05-28 |
| PL90346B1 (en:Method) | 1977-01-31 |
| ZA724841B (en) | 1974-02-27 |
| US3859282A (en) | 1975-01-07 |
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