ES402678A1 - Metodo para producir nuevos derivados de triptofano. - Google Patents
Metodo para producir nuevos derivados de triptofano.Info
- Publication number
- ES402678A1 ES402678A1 ES402678A ES402678A ES402678A1 ES 402678 A1 ES402678 A1 ES 402678A1 ES 402678 A ES402678 A ES 402678A ES 402678 A ES402678 A ES 402678A ES 402678 A1 ES402678 A1 ES 402678A1
- Authority
- ES
- Spain
- Prior art keywords
- tryptophan
- formula
- substituents
- mono
- poly
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical class C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 title abstract 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 2
- 229910052784 alkaline earth metal Inorganic materials 0.000 abstract 2
- 125000001424 substituent group Chemical group 0.000 abstract 2
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 abstract 1
- -1 COOC2H5 Chemical group 0.000 abstract 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 1
- QIVBCDIJIAJPQS-UHFFFAOYSA-N Tryptophan Natural products C1=CC=C2C(CC(N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-UHFFFAOYSA-N 0.000 abstract 1
- 239000003513 alkali Substances 0.000 abstract 1
- 150000001342 alkaline earth metals Chemical class 0.000 abstract 1
- 239000012736 aqueous medium Substances 0.000 abstract 1
- 239000008346 aqueous phase Substances 0.000 abstract 1
- 239000007795 chemical reaction product Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical compound [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 abstract 1
- 125000006289 hydroxybenzyl group Chemical class 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 125000000896 monocarboxylic acid group Chemical group 0.000 abstract 1
- 150000007530 organic bases Chemical group 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT6865271A IT1055518B (it) | 1971-05-18 | 1971-05-18 | Derivatives del triptofano |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES402678A1 true ES402678A1 (es) | 1975-04-01 |
Family
ID=11310165
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES402678A Expired ES402678A1 (es) | 1971-05-18 | 1972-05-12 | Metodo para producir nuevos derivados de triptofano. |
Country Status (7)
| Country | Link |
|---|---|
| JP (1) | JPS5139220B2 (cs) |
| DE (1) | DE2224130C3 (cs) |
| ES (1) | ES402678A1 (cs) |
| FR (1) | FR2138046B1 (cs) |
| GB (1) | GB1352472A (cs) |
| IT (1) | IT1055518B (cs) |
| NL (1) | NL173167C (cs) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4000297A (en) * | 1971-05-18 | 1976-12-28 | Rotta Research Laboratorium S.P.A. | N-p-chlorobenzoyl tryptophane, salts and compositions thereof |
| FR2499076A1 (fr) * | 1981-02-02 | 1982-08-06 | Panmedica Laboratoires | Nouveaux derives de l'acide ((indol-3 yl)-3 amino-2 propionyloxy)-2 acetique, procedes pour leur preparation et medicaments les contenant |
| US4694017A (en) * | 1983-05-19 | 1987-09-15 | Otsuka Pharmaceutical Co., Ltd. | 2-amido 3(oxindol-3-yl)propionic acids having antiulcer activity |
| IT1179866B (it) * | 1984-12-12 | 1987-09-16 | Rotta Research Lab | Derivati del triptofano farmaceuticamente attivi e composizioni farmaceutiche che li contengono |
| US4764381A (en) * | 1985-12-06 | 1988-08-16 | Key Pharmaceuticals, Inc. | Percutaneous penetration enhancer of oleic acid and 2-ethyl-1, 3-hexanediol |
| JPH03503650A (ja) * | 1988-04-05 | 1991-08-15 | アボツト・ラボラトリーズ | Ｃｃｋアンタゴニストとしてのトリプトファン誘導体 |
| GB2282807A (en) * | 1993-10-15 | 1995-04-19 | Merck & Co Inc | Tryptophan esters and amides as tachykinin receptor antagonists |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2380479A (en) * | 1941-06-06 | 1945-07-31 | Eric T Stiller | dl-tryptophane and processes for producing the same |
-
1971
- 1971-05-18 IT IT6865271A patent/IT1055518B/it active
-
1972
- 1972-03-14 GB GB1191072A patent/GB1352472A/en not_active Expired
- 1972-05-12 ES ES402678A patent/ES402678A1/es not_active Expired
- 1972-05-17 JP JP4827672A patent/JPS5139220B2/ja not_active Expired
- 1972-05-17 DE DE19722224130 patent/DE2224130C3/de not_active Expired
- 1972-05-17 NL NL7206680A patent/NL173167C/xx not_active IP Right Cessation
- 1972-05-17 FR FR7217675A patent/FR2138046B1/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| GB1352472A (en) | 1974-05-08 |
| IT1055518B (it) | 1982-01-11 |
| DE2224130B2 (de) | 1979-11-08 |
| DE2224130C3 (de) | 1980-07-17 |
| FR2138046B1 (cs) | 1975-06-20 |
| JPS4848462A (cs) | 1973-07-09 |
| NL173167B (nl) | 1983-07-18 |
| NL173167C (nl) | 1983-12-16 |
| JPS5139220B2 (cs) | 1976-10-26 |
| FR2138046A1 (cs) | 1972-12-29 |
| DE2224130A1 (de) | 1972-11-30 |
| NL7206680A (cs) | 1972-11-21 |
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