ES402302A1 - Procedimiento para la preparacion de nuevas tieno (3,2-d) pirimidinas. - Google Patents

Procedimiento para la preparacion de nuevas tieno (3,2-d) pirimidinas.

Info

Publication number
ES402302A1
ES402302A1 ES402302A ES402302A ES402302A1 ES 402302 A1 ES402302 A1 ES 402302A1 ES 402302 A ES402302 A ES 402302A ES 402302 A ES402302 A ES 402302A ES 402302 A1 ES402302 A1 ES 402302A1
Authority
ES
Spain
Prior art keywords
pyrimidines
thiomorpholino
preparation
groups
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES402302A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19712121950 external-priority patent/DE2121950A1/de
Priority claimed from DE19712137341 external-priority patent/DE2137341A1/de
Priority claimed from DE19722215299 external-priority patent/DE2215299A1/de
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of ES402302A1 publication Critical patent/ES402302A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
ES402302A 1971-05-04 1972-05-02 Procedimiento para la preparacion de nuevas tieno (3,2-d) pirimidinas. Expired ES402302A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19712121950 DE2121950A1 (en) 1971-05-04 1971-05-04 Thieno(3,2-d)pyrimidine derivs - with thrombocyte aggregation inhibiting activity
DE19712137341 DE2137341A1 (de) 1971-07-26 1971-07-26 Neue thieno eckige klammer auf 3,2-d eckige klammer zu pyrimidine
DE19722215299 DE2215299A1 (de) 1972-03-29 1972-03-29 Neue thieno eckige klammer auf 3,2-d eckige klammer zu pyrimidine

Publications (1)

Publication Number Publication Date
ES402302A1 true ES402302A1 (es) 1975-04-01

Family

ID=27183398

Family Applications (1)

Application Number Title Priority Date Filing Date
ES402302A Expired ES402302A1 (es) 1971-05-04 1972-05-02 Procedimiento para la preparacion de nuevas tieno (3,2-d) pirimidinas.

Country Status (15)

Country Link
US (1) US3888851A (forum.php)
AT (1) AT318619B (forum.php)
AU (1) AU4181572A (forum.php)
BE (1) BE783044A (forum.php)
BG (1) BG20593A3 (forum.php)
DD (1) DD97656A5 (forum.php)
DK (1) DK129844B (forum.php)
ES (1) ES402302A1 (forum.php)
FR (1) FR2135294B1 (forum.php)
GB (1) GB1393161A (forum.php)
HU (1) HU163960B (forum.php)
IL (1) IL39341A (forum.php)
NL (1) NL7206041A (forum.php)
PL (1) PL82381B1 (forum.php)
RO (1) RO62428A (forum.php)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4054656A (en) * 1975-09-10 1977-10-18 Mead Johnson & Company Thieno[2,3-d]pyrimidine antiallergic agents
US5098902A (en) * 1991-03-18 1992-03-24 Warner-Lambert Company Method of treating neurodegenerative diseases
FI943798A0 (fi) * 1992-02-19 1994-08-18 Pfizer Kasvaimenvastaisen vaikutuksen lisäämiseen tarkoitettuja heterosyklisiä yhdisteitä
KR100378937B1 (ko) 1997-10-20 2003-05-09 에프. 호프만-라 로슈 아게 바이사이클릭 키나아제 억제제
US6187777B1 (en) 1998-02-06 2001-02-13 Amgen Inc. Compounds and methods which modulate feeding behavior and related diseases
GB0423653D0 (en) 2004-10-25 2004-11-24 Piramed Ltd Pharmaceutical compounds
BRPI0608387A2 (pt) * 2006-04-19 2009-12-29 Boehringer Ingelheim Int compostos para o tratamento de doenças inflamatórias
CL2007001166A1 (es) 2006-04-26 2008-01-25 Piramed Ltd Compuestos derivados de pirimidina condensada, inhibidores de pi3-quinasa; procesos para preparar los compuestos; composicion farmaceutica que los comprende; uso de los compuestos en la preparacion de medicamentos; proceso para preparar la composicion farmaceutica; y kit que incluye a la composicion farmaceutica
CN101472930B (zh) 2006-04-26 2011-12-14 霍夫曼-拉罗奇有限公司 用作PI3K抑制剂的噻吩并[3,2-d]嘧啶的衍生物
PT2041139E (pt) 2006-04-26 2012-01-13 Hoffmann La Roche Compostos farmacêuticos
BRPI0717923A2 (pt) 2006-12-07 2013-10-22 Genentech In '' composto, composição farmacêutica, método para tratar um câncer, processo para a produção de uma composição farmacêutica, usos, métodos para inibir ou modular a atividade da lipídeo quinase e kit ' '
ZA200904531B (en) 2006-12-07 2010-09-29 Hoffmann La Roche Phosphoinositide 3-kinase inhibitor compounds and methods of use
EP2207781B1 (en) 2007-09-24 2012-11-28 Genentech, Inc. Thiazolopyrimidine p13k inhibitor compounds and methods of use
NZ585348A (en) * 2007-10-19 2012-02-24 Boehringer Ingelheim Int Heterocycle-substituted piperazino-dihydrothienopyrimidines
EP2214675B1 (en) 2007-10-25 2013-11-20 Genentech, Inc. Process for making thienopyrimidine compounds
GB0721095D0 (en) 2007-10-26 2007-12-05 Piramed Ltd Pharmaceutical compounds
AU2010224125B2 (en) 2009-03-12 2015-05-14 Genentech, Inc. Combinations of phosphoinositide 3-kinase inhibitor compounds and chemotherapeutic agents for the treatment of hematopoietic malignancies
WO2010136491A1 (en) * 2009-05-27 2010-12-02 F. Hoffmann-La Roche Ag Bicyclic indole-pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use
EP2435438A1 (en) 2009-05-27 2012-04-04 Genentech, Inc. Bicyclic pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use
WO2011130654A1 (en) 2010-04-16 2011-10-20 Genentech, Inc. Fox03a as predictive biomarker for pi3k/akt kinase pathway inhibitor efficacy
US20140004209A1 (en) 2010-12-22 2014-01-02 Genentech, Inc. Autophagy inducer and inhibitor combination therapy for the treatment of neoplasms
MX369175B (es) 2013-02-25 2019-10-30 Genentech Inc Métodos para detectar mutantes de akt resistentes a fármacos.
GB201410816D0 (en) * 2014-06-17 2014-07-30 Ucb Biopharma Sprl And Katholieke Universiteit Leuven Therapeutic agents

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3259623A (en) * 1963-06-14 1966-07-05 Olin Mathieson Process for preparing 2-(secondary amino)-halogenopyrimidines
DE1470356A1 (de) * 1964-01-15 1970-04-30 Thomae Gmbh Dr K Neue Thieno[3,2-d]pyrimidine und Verfahren zu ihrer Herstellung
US3210368A (en) * 1964-09-29 1965-10-05 Ciba Geigy Corp Certain 2-amino-4-aryl-5-n, n-disubstituted amino-lower alkyl-thiazole compounds

Also Published As

Publication number Publication date
GB1393161A (en) 1975-05-07
DK129844C (forum.php) 1975-05-12
FR2135294A1 (forum.php) 1972-12-15
IL39341A (en) 1975-08-31
AT318619B (de) 1974-11-11
IL39341A0 (en) 1972-07-26
FR2135294B1 (forum.php) 1975-10-17
DD97656A5 (forum.php) 1973-05-12
NL7206041A (forum.php) 1972-11-07
RO62428A (fr) 1978-01-15
BG20593A3 (bg) 1975-12-05
US3888851A (en) 1975-06-10
BE783044A (fr) 1972-11-06
PL82381B1 (forum.php) 1975-10-31
AU4181572A (en) 1973-11-08
HU163960B (forum.php) 1973-11-28
DK129844B (da) 1974-11-25

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