BG20593A3 - Метод за получаване на тиено<3,2-д>пиримидини - Google Patents

Метод за получаване на тиено<3,2-д>пиримидини

Info

Publication number
BG20593A3
BG20593A3 BG020371A BG2037172A BG20593A3 BG 20593 A3 BG20593 A3 BG 20593A3 BG 020371 A BG020371 A BG 020371A BG 2037172 A BG2037172 A BG 2037172A BG 20593 A3 BG20593 A3 BG 20593A3
Authority
BG
Bulgaria
Prior art keywords
pyrimidines
thieno
obtaining
obtaining thieno
Prior art date
Application number
BG020371A
Other languages
Bulgarian (bg)
English (en)
Inventor
Berthold Narr
Josef Roch
Erich Muller
Josef Nickl
Original Assignee
Dr. Karl Thomae Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19712121950 external-priority patent/DE2121950A1/de
Priority claimed from DE19712137341 external-priority patent/DE2137341A1/de
Priority claimed from DE19722215299 external-priority patent/DE2215299A1/de
Application filed by Dr. Karl Thomae Gmbh filed Critical Dr. Karl Thomae Gmbh
Publication of BG20593A3 publication Critical patent/BG20593A3/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
BG020371A 1971-05-04 1972-05-03 Метод за получаване на тиено<3,2-д>пиримидини BG20593A3 (bg)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19712121950 DE2121950A1 (en) 1971-05-04 1971-05-04 Thieno(3,2-d)pyrimidine derivs - with thrombocyte aggregation inhibiting activity
DE19712137341 DE2137341A1 (de) 1971-07-26 1971-07-26 Neue thieno eckige klammer auf 3,2-d eckige klammer zu pyrimidine
DE19722215299 DE2215299A1 (de) 1972-03-29 1972-03-29 Neue thieno eckige klammer auf 3,2-d eckige klammer zu pyrimidine

Publications (1)

Publication Number Publication Date
BG20593A3 true BG20593A3 (bg) 1975-12-05

Family

ID=27183398

Family Applications (1)

Application Number Title Priority Date Filing Date
BG020371A BG20593A3 (bg) 1971-05-04 1972-05-03 Метод за получаване на тиено<3,2-д>пиримидини

Country Status (15)

Country Link
US (1) US3888851A (forum.php)
AT (1) AT318619B (forum.php)
AU (1) AU4181572A (forum.php)
BE (1) BE783044A (forum.php)
BG (1) BG20593A3 (forum.php)
DD (1) DD97656A5 (forum.php)
DK (1) DK129844B (forum.php)
ES (1) ES402302A1 (forum.php)
FR (1) FR2135294B1 (forum.php)
GB (1) GB1393161A (forum.php)
HU (1) HU163960B (forum.php)
IL (1) IL39341A (forum.php)
NL (1) NL7206041A (forum.php)
PL (1) PL82381B1 (forum.php)
RO (1) RO62428A (forum.php)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4054656A (en) * 1975-09-10 1977-10-18 Mead Johnson & Company Thieno[2,3-d]pyrimidine antiallergic agents
US5098902A (en) * 1991-03-18 1992-03-24 Warner-Lambert Company Method of treating neurodegenerative diseases
WO1993017021A1 (en) * 1992-02-19 1993-09-02 Pfizer, Inc. Heterocyclic compounds for enhancing antitumor activity
JP3579350B2 (ja) 1997-10-20 2004-10-20 エフ．ホフマン−ラ ロシュ アーゲー 二環式キナーゼ阻害剤
US6187777B1 (en) 1998-02-06 2001-02-13 Amgen Inc. Compounds and methods which modulate feeding behavior and related diseases
GB0423653D0 (en) 2004-10-25 2004-11-24 Piramed Ltd Pharmaceutical compounds
KR101335964B1 (ko) * 2005-04-21 2013-12-04 베링거 인겔하임 인터내셔날 게엠베하 염증성 질환 치료용 디하이드로티에노피리미딘
AU2007243457B2 (en) 2006-04-26 2012-02-23 F. Hoffmann-La Roche Ag Pharmaceutical compounds
WO2007127183A1 (en) 2006-04-26 2007-11-08 Genentech, Inc. Phosphoinositide 3-kinase inhibitor compounds and pharmaceutical compositions containing them
DE602007007323D1 (de) 2006-04-26 2010-08-05 Hoffmann La Roche Thienoä3,2-düpyrimidin-derivat geeignet als pi3k inhibitor
ZA200904531B (en) 2006-12-07 2010-09-29 Hoffmann La Roche Phosphoinositide 3-kinase inhibitor compounds and methods of use
CL2007003520A1 (es) 2006-12-07 2008-08-22 Piramed Ltd Genentech Inc Compuestos derivados de heterociclos sustituidos con morfolina, inhibidores de la actividad pi3 quinasa; composicion farmaceutica que comprende a dichos compuestos; kit farmaceutico; y su uso para el tratamiento profilactico o terapeutico del cancer.
CN101932587A (zh) 2007-09-24 2010-12-29 吉宁特有限公司 噻唑并嘧啶pi3k抑制剂化合物及使用方法
KR20100075930A (ko) * 2007-10-19 2010-07-05 베링거 인겔하임 인터내셔날 게엠베하 헤테로사이클-치환된 피페라지노-디하이드로티에노피리미딘
CN101909631B (zh) 2007-10-25 2012-09-12 健泰科生物技术公司 制备噻吩并嘧啶化合物的方法
GB0721095D0 (en) 2007-10-26 2007-12-05 Piramed Ltd Pharmaceutical compounds
CN102369011A (zh) 2009-03-12 2012-03-07 健泰科生物技术公司 用于治疗造血恶性肿瘤的磷酸肌醇3-激酶抑制剂化合物与化学治疗剂的组合
SG182247A1 (en) * 2009-05-27 2012-08-30 Hoffmann La Roche Bicyclic indole-pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use
US8173650B2 (en) * 2009-05-27 2012-05-08 Genentech, Inc. Bicyclic pyrimidine PI3K inhibitor compounds selective for P110 delta, and methods of use
RU2012148699A (ru) 2010-04-16 2014-05-27 Дженентек, Инк. Foxo3a как прогностический биомаркер для эффективности ингибитора пути киназы pi3k/акт
WO2012088254A1 (en) 2010-12-22 2012-06-28 Genentech, Inc. Autophagy inducer and inhibitor combination therapy for the treatment of neoplasms
CA2901126C (en) 2013-02-25 2022-01-25 Genentech, Inc. Methods and compositions for detecting and treating drug resistant akt mutant
GB201410816D0 (en) * 2014-06-17 2014-07-30 Ucb Biopharma Sprl And Katholieke Universiteit Leuven Therapeutic agents

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3259623A (en) * 1963-06-14 1966-07-05 Olin Mathieson Process for preparing 2-(secondary amino)-halogenopyrimidines
DE1470356A1 (de) * 1964-01-15 1970-04-30 Thomae Gmbh Dr K Neue Thieno[3,2-d]pyrimidine und Verfahren zu ihrer Herstellung
US3210368A (en) * 1964-09-29 1965-10-05 Ciba Geigy Corp Certain 2-amino-4-aryl-5-n, n-disubstituted amino-lower alkyl-thiazole compounds

Also Published As

Publication number Publication date
BE783044A (fr) 1972-11-06
AU4181572A (en) 1973-11-08
DD97656A5 (forum.php) 1973-05-12
AT318619B (de) 1974-11-11
DK129844B (da) 1974-11-25
GB1393161A (en) 1975-05-07
NL7206041A (forum.php) 1972-11-07
US3888851A (en) 1975-06-10
PL82381B1 (forum.php) 1975-10-31
RO62428A (fr) 1978-01-15
DK129844C (forum.php) 1975-05-12
IL39341A0 (en) 1972-07-26
ES402302A1 (es) 1975-04-01
HU163960B (forum.php) 1973-11-28
IL39341A (en) 1975-08-31
FR2135294A1 (forum.php) 1972-12-15
FR2135294B1 (forum.php) 1975-10-17

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