ES401941A1 - Procedimiento para la preparacion de 1,2,3,4-tetrahidroisoquinolinas - Google Patents

Procedimiento para la preparacion de 1,2,3,4-tetrahidroisoquinolinas

Info

Publication number
ES401941A1
ES401941A1 ES0401941A ES401941A ES401941A1 ES 401941 A1 ES401941 A1 ES 401941A1 ES 0401941 A ES0401941 A ES 0401941A ES 401941 A ES401941 A ES 401941A ES 401941 A1 ES401941 A1 ES 401941A1
Authority
ES
Spain
Prior art keywords
formula
translation
preparation
machine
legally binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0401941A
Other languages
English (en)
Inventor
Giangiacomo Massaroli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Poli Industria Chimica SpA
Original Assignee
Poli Industria Chimica SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Poli Industria Chimica SpA filed Critical Poli Industria Chimica SpA
Publication of ES401941A1 publication Critical patent/ES401941A1/es
Expired legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Procedimiento para la preparación de 1,2,3,4-tetrahidroisoquinolinas, y en especial del 3- fenil-5(2[2-(1,2,3,4-tetrahidroisoquinolinil)-etil])-1,2,4-oxadiazoles, componente activo en formulaciones para el tratamiento clínico de afecciones en las vías respitarorias de la fórmula general **fórmula** en la que R representa hidrógeno o un grupo de metoxilo, R'' representa hidrógeno , metilo, etilo o n-propilo y R''` representa hidrógeno o metilo, caracterizado por el hecho de que se hace reaccionar beta-cloropropionil-benzamidoxima con una tetrahidroisoquinolina de la fórmula **fórmula** donde los substituyentes tienen el mismo significado antes expuesto en presencia de una sustancia apta para captar el ácido clorhídrico eliminando el agua, que se forma en el curso de la reacción , mediante destilación azeotrópica con benceno
ES0401941A 1971-04-22 1972-04-20 Procedimiento para la preparacion de 1,2,3,4-tetrahidroisoquinolinas Expired ES401941A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2352871A IT1043838B (it) 1971-04-22 1971-04-22 1 2 3 4 tetraidroisochinoline e processo per la loro preparazione

Publications (1)

Publication Number Publication Date
ES401941A1 true ES401941A1 (es) 1975-03-01

Family

ID=11207867

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0401941A Expired ES401941A1 (es) 1971-04-22 1972-04-20 Procedimiento para la preparacion de 1,2,3,4-tetrahidroisoquinolinas

Country Status (8)

Country Link
AR (1) AR192360A1 (es)
BE (1) BE782182A (es)
DE (1) DE2219418B2 (es)
ES (1) ES401941A1 (es)
FR (1) FR2134047B1 (es)
GB (1) GB1381959A (es)
IT (1) IT1043838B (es)
ZA (1) ZA722503B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU180708B (en) * 1979-10-11 1983-04-29 Chinoin Gyogyszer Es Vegyeszet Process for preparing new 1,2,4-oxadiazine derivatives
GB8529546D0 (en) * 1985-11-30 1986-01-08 Beecham Group Plc Compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL256329A (es) * 1959-09-29

Also Published As

Publication number Publication date
FR2134047B1 (es) 1975-12-26
IT1043838B (it) 1980-02-29
FR2134047A1 (es) 1972-12-01
DE2219418B2 (de) 1974-03-14
ZA722503B (en) 1973-07-25
DE2219418C3 (es) 1974-10-10
AR192360A1 (es) 1973-02-14
DE2219418A1 (de) 1972-11-02
GB1381959A (en) 1975-01-29
BE782182A (fr) 1972-07-31

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