ES401273A1 - Procedimiento para la preparacion de 4 - hidroxi - 1 - fe- nil - 2 - pirrolidino-pentano, sus diastereoisomeros y sus sales. - Google Patents
Procedimiento para la preparacion de 4 - hidroxi - 1 - fe- nil - 2 - pirrolidino-pentano, sus diastereoisomeros y sus sales.Info
- Publication number
- ES401273A1 ES401273A1 ES401273A ES401273A ES401273A1 ES 401273 A1 ES401273 A1 ES 401273A1 ES 401273 A ES401273 A ES 401273A ES 401273 A ES401273 A ES 401273A ES 401273 A1 ES401273 A1 ES 401273A1
- Authority
- ES
- Spain
- Prior art keywords
- hydroxy
- phenyl
- pyrrolidino
- formula
- pentane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- GESALGPTLHAAET-UHFFFAOYSA-N 5-phenyl-4-pyrrolidin-1-ylpentan-2-ol Chemical compound OC(CC(CC1=CC=CC=C1)N1CCCC1)C GESALGPTLHAAET-UHFFFAOYSA-N 0.000 title abstract 4
- 150000003839 salts Chemical class 0.000 title abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- 150000007522 mineralic acids Chemical class 0.000 abstract 2
- 150000007524 organic acids Chemical class 0.000 abstract 2
- XGIURHJOBRDSFE-UHFFFAOYSA-N 4-hydroxy-2-pyrrolidin-1-ylbutanenitrile Chemical compound OCCC(C#N)N1CCCC1 XGIURHJOBRDSFE-UHFFFAOYSA-N 0.000 abstract 1
- -1 benzyl magnesium halide Chemical class 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyrrole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19712115281 DE2115281A1 (de) | 1971-03-30 | 1971-03-30 | 4-Hydroxy- l-phenyl-2-pyrrolidino-pentan, dessen Diastereomere und Salze und Verfahren zur Herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES401273A1 true ES401273A1 (es) | 1975-02-01 |
Family
ID=5803191
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES401273A Expired ES401273A1 (es) | 1971-03-30 | 1972-03-28 | Procedimiento para la preparacion de 4 - hidroxi - 1 - fe- nil - 2 - pirrolidino-pentano, sus diastereoisomeros y sus sales. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US3801592A (https=) |
| AT (1) | AT310730B (https=) |
| BE (1) | BE781423A (https=) |
| CA (1) | CA967968A (https=) |
| DE (1) | DE2115281A1 (https=) |
| ES (1) | ES401273A1 (https=) |
| FR (1) | FR2132244B1 (https=) |
| GB (1) | GB1379959A (https=) |
| IL (1) | IL39100A (https=) |
| NL (1) | NL7204230A (https=) |
| ZA (1) | ZA722161B (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8304613D0 (en) * | 1983-02-18 | 1983-03-23 | Ici Plc | Chemical process |
| WO2025072342A1 (en) * | 2023-09-26 | 2025-04-03 | Bexson Biomedical, Inc. | (hetero)arylalkylamine n-methyl-d-aspartate receptor (nmdar) antagonists and uses thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH344418A (de) * | 1955-07-01 | 1960-02-15 | Thomae Gmbh Dr K | Verfahren zur Herstellung tertiärer Amine |
-
1971
- 1971-03-30 DE DE19712115281 patent/DE2115281A1/de active Pending
-
1972
- 1972-03-27 US US00238660A patent/US3801592A/en not_active Expired - Lifetime
- 1972-03-28 IL IL39100A patent/IL39100A/xx unknown
- 1972-03-28 ES ES401273A patent/ES401273A1/es not_active Expired
- 1972-03-29 CA CA138,421A patent/CA967968A/en not_active Expired
- 1972-03-29 GB GB1488872A patent/GB1379959A/en not_active Expired
- 1972-03-29 NL NL7204230A patent/NL7204230A/xx unknown
- 1972-03-29 ZA ZA722161A patent/ZA722161B/xx unknown
- 1972-03-29 BE BE781423A patent/BE781423A/xx unknown
- 1972-03-29 AT AT273972A patent/AT310730B/de not_active IP Right Cessation
- 1972-03-30 FR FR7211260A patent/FR2132244B1/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| NL7204230A (https=) | 1972-10-03 |
| DE2115281A1 (de) | 1972-10-19 |
| ZA722161B (en) | 1973-12-19 |
| AT310730B (de) | 1973-10-10 |
| US3801592A (en) | 1974-04-02 |
| BE781423A (fr) | 1972-09-29 |
| FR2132244B1 (https=) | 1975-08-01 |
| IL39100A (en) | 1975-05-22 |
| FR2132244A1 (https=) | 1972-11-17 |
| IL39100A0 (en) | 1972-05-30 |
| CA967968A (en) | 1975-05-20 |
| GB1379959A (en) | 1975-01-08 |
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