CA967968A - 4-hydroxy-1-phenyl-2-pyrrolidinopentane, their diastereomers and salts and processes for their preparation - Google Patents

4-hydroxy-1-phenyl-2-pyrrolidinopentane, their diastereomers and salts and processes for their preparation

Info

Publication number
CA967968A
CA967968A CA138,421A CA138421A CA967968A CA 967968 A CA967968 A CA 967968A CA 138421 A CA138421 A CA 138421A CA 967968 A CA967968 A CA 967968A
Authority
CA
Canada
Prior art keywords
pyrrolidinopentane
diastereomers
hydroxy
phenyl
salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA138,421A
Other languages
English (en)
Other versions
CA138421S (en
Inventor
Ernst Seeger
Wolfhard Engel
Joachim Kahling
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Application granted granted Critical
Publication of CA967968A publication Critical patent/CA967968A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA138,421A 1971-03-30 1972-03-29 4-hydroxy-1-phenyl-2-pyrrolidinopentane, their diastereomers and salts and processes for their preparation Expired CA967968A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19712115281 DE2115281A1 (de) 1971-03-30 1971-03-30 4-Hydroxy- l-phenyl-2-pyrrolidino-pentan, dessen Diastereomere und Salze und Verfahren zur Herstellung

Publications (1)

Publication Number Publication Date
CA967968A true CA967968A (en) 1975-05-20

Family

ID=5803191

Family Applications (1)

Application Number Title Priority Date Filing Date
CA138,421A Expired CA967968A (en) 1971-03-30 1972-03-29 4-hydroxy-1-phenyl-2-pyrrolidinopentane, their diastereomers and salts and processes for their preparation

Country Status (11)

Country Link
US (1) US3801592A (https=)
AT (1) AT310730B (https=)
BE (1) BE781423A (https=)
CA (1) CA967968A (https=)
DE (1) DE2115281A1 (https=)
ES (1) ES401273A1 (https=)
FR (1) FR2132244B1 (https=)
GB (1) GB1379959A (https=)
IL (1) IL39100A (https=)
NL (1) NL7204230A (https=)
ZA (1) ZA722161B (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8304613D0 (en) * 1983-02-18 1983-03-23 Ici Plc Chemical process
WO2025072342A1 (en) * 2023-09-26 2025-04-03 Bexson Biomedical, Inc. (hetero)arylalkylamine n-methyl-d-aspartate receptor (nmdar) antagonists and uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH344418A (de) * 1955-07-01 1960-02-15 Thomae Gmbh Dr K Verfahren zur Herstellung tertiärer Amine

Also Published As

Publication number Publication date
NL7204230A (https=) 1972-10-03
DE2115281A1 (de) 1972-10-19
ZA722161B (en) 1973-12-19
AT310730B (de) 1973-10-10
US3801592A (en) 1974-04-02
BE781423A (fr) 1972-09-29
FR2132244B1 (https=) 1975-08-01
IL39100A (en) 1975-05-22
ES401273A1 (es) 1975-02-01
FR2132244A1 (https=) 1972-11-17
IL39100A0 (en) 1972-05-30
GB1379959A (en) 1975-01-08

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