ES399271A1 - 4-tertiary-n-aminomethyl-2-methyl-2-4,6,7-trimethoxy-5-benzofuranyl- 1,3-dioxolanes their bromomethylates their process of preparation and their therapeutic application - Google Patents

4-tertiary-n-aminomethyl-2-methyl-2-4,6,7-trimethoxy-5-benzofuranyl- 1,3-dioxolanes their bromomethylates their process of preparation and their therapeutic application

Info

Publication number
ES399271A1
ES399271A1 ES399271A ES399271A ES399271A1 ES 399271 A1 ES399271 A1 ES 399271A1 ES 399271 A ES399271 A ES 399271A ES 399271 A ES399271 A ES 399271A ES 399271 A1 ES399271 A1 ES 399271A1
Authority
ES
Spain
Prior art keywords
methyl
formula
trimethoxy
bromomethylates
tertiary
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES399271A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Delalande SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delalande SA filed Critical Delalande SA
Publication of ES399271A1 publication Critical patent/ES399271A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/86—Benzo [b] furans; Hydrogenated benzo [b] furans with an oxygen atom directly attached in position 7
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/28—Radicals substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Procedure for the preparation of new bromomethylates of (N-amino-tertiary-methyl) -4-methyl-2- (trimethoxy-4', 6', 7'-benzofuran-5'-yl) -2-dioxolane-1,3 of formula : ** (See formula) ** in which R1 and R2 represent: or, each, a lower alcohol group comprising from 1 to 4 carbon atoms; or, with the nitrogen atom to which they are attached, a heterocyclic radical chosen from the following: piperidino, pyrrolidino, hexamethyleneimino and morfolino, which consists of condensing, in benzene medium, bromomethyl-4-methyl-2 (trimethoxy-4', 6', 7'-benzofuran-5'-yl) -2-dioxolane-1,3 of formula: ** (See formula) ** with a secondary amine of formula: ** (See formula) ** in which R1 and R2 have the same meanings as in formula (I) and then subject the obtained compounds to the action of methyl bromide in an ether medium. (Machine-translation by Google Translate, not legally binding)
ES399271A 1971-01-29 1972-01-28 4-tertiary-n-aminomethyl-2-methyl-2-4,6,7-trimethoxy-5-benzofuranyl- 1,3-dioxolanes their bromomethylates their process of preparation and their therapeutic application Expired ES399271A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7102927A FR2123198B1 (en) 1971-01-29 1971-01-29

Publications (1)

Publication Number Publication Date
ES399271A1 true ES399271A1 (en) 1975-01-01

Family

ID=9071077

Family Applications (1)

Application Number Title Priority Date Filing Date
ES399271A Expired ES399271A1 (en) 1971-01-29 1972-01-28 4-tertiary-n-aminomethyl-2-methyl-2-4,6,7-trimethoxy-5-benzofuranyl- 1,3-dioxolanes their bromomethylates their process of preparation and their therapeutic application

Country Status (9)

Country Link
BE (1) BE777926A (en)
CA (1) CA987324A (en)
CH (1) CH535230A (en)
ES (1) ES399271A1 (en)
FR (1) FR2123198B1 (en)
GB (1) GB1315279A (en)
IT (1) IT1052680B (en)
LU (1) LU64597A1 (en)
NL (1) NL7200826A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3305769A1 (en) * 1982-06-04 1983-12-08 Bayer Ag, 5090 Leverkusen PEST CONTROL

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR5803E (en) * 1905-06-16 1906-12-31 Joseph Greffe Radiator system easily removable and taking up minimal space

Also Published As

Publication number Publication date
NL7200826A (en) 1972-08-01
FR2123198A1 (en) 1972-09-08
FR2123198B1 (en) 1974-04-12
IT1052680B (en) 1981-07-20
CA987324A (en) 1976-04-13
GB1315279A (en) 1973-05-02
BE777926A (en) 1972-07-11
CH535230A (en) 1973-03-31
LU64597A1 (en) 1972-08-23

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