ES398109A1 - Un metodo para la preparacion de una composicion de aneste-sico local. - Google Patents
Un metodo para la preparacion de una composicion de aneste-sico local.Info
- Publication number
- ES398109A1 ES398109A1 ES398109A ES398109A ES398109A1 ES 398109 A1 ES398109 A1 ES 398109A1 ES 398109 A ES398109 A ES 398109A ES 398109 A ES398109 A ES 398109A ES 398109 A1 ES398109 A1 ES 398109A1
- Authority
- ES
- Spain
- Prior art keywords
- aqueous solution
- local anesthetic
- tetrodotoxin
- pharmaceutical composition
- aminoalcohilbenzoates
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 239000007864 aqueous solution Substances 0.000 abstract 3
- 239000003589 local anesthetic agent Substances 0.000 abstract 3
- ZPUCINDJVBIVPJ-LJISPDSOSA-N cocaine Chemical compound O([C@H]1C[C@@H]2CC[C@@H](N2C)[C@H]1C(=O)OC)C(=O)C1=CC=CC=C1 ZPUCINDJVBIVPJ-LJISPDSOSA-N 0.000 abstract 2
- CFMYXEVWODSLAX-QOZOJKKESA-N tetrodotoxin Chemical compound O([C@@]([C@H]1O)(O)O[C@H]2[C@@]3(O)CO)[C@H]3[C@@H](O)[C@]11[C@H]2[C@@H](O)N=C(N)N1 CFMYXEVWODSLAX-QOZOJKKESA-N 0.000 abstract 2
- 229950010357 tetrodotoxin Drugs 0.000 abstract 2
- CFMYXEVWODSLAX-UHFFFAOYSA-N tetrodotoxin Natural products C12C(O)NC(=N)NC2(C2O)C(O)C3C(CO)(O)C1OC2(O)O3 CFMYXEVWODSLAX-UHFFFAOYSA-N 0.000 abstract 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical class NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 1
- 230000003444 anaesthetic effect Effects 0.000 abstract 1
- OWIUPIRUAQMTTK-UHFFFAOYSA-N carbazic acid Chemical class NNC(O)=O OWIUPIRUAQMTTK-UHFFFAOYSA-N 0.000 abstract 1
- 229960003920 cocaine Drugs 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- COVOMQKTVSVWBZ-CJCGOCGYSA-N deoxytetrodotoxin Chemical compound O1C(C2(O)CO)(O)OC3C(O)C1[C@@H]1CN=C(N)NC12C3O COVOMQKTVSVWBZ-CJCGOCGYSA-N 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- SBOJXQVPLKSXOG-UHFFFAOYSA-N o-amino-hydroxylamine Chemical class NON SBOJXQVPLKSXOG-UHFFFAOYSA-N 0.000 abstract 1
- 230000002035 prolonged effect Effects 0.000 abstract 1
- 239000003053 toxin Substances 0.000 abstract 1
- 231100000765 toxin Toxicity 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10994271A | 1971-01-26 | 1971-01-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES398109A1 true ES398109A1 (es) | 1975-03-16 |
Family
ID=22330411
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES398109A Expired ES398109A1 (es) | 1971-01-26 | 1971-12-18 | Un metodo para la preparacion de una composicion de aneste-sico local. |
| ES398108A Expired ES398108A1 (es) | 1971-01-26 | 1971-12-18 | Un metodo para la preparacion de una composicion de aneste-sico local. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES398108A Expired ES398108A1 (es) | 1971-01-26 | 1971-12-18 | Un metodo para la preparacion de una composicion de aneste-sico local. |
Country Status (18)
| Country | Link |
|---|---|
| AT (2) | AT310938B (enExample) |
| AU (1) | AU465875B2 (enExample) |
| BE (2) | BE776769A (enExample) |
| BR (2) | BR7108428D0 (enExample) |
| CA (2) | CA983850A (enExample) |
| DD (2) | DD96400A5 (enExample) |
| DE (2) | DE2163055A1 (enExample) |
| DK (2) | DK130389B (enExample) |
| ES (2) | ES398109A1 (enExample) |
| FR (2) | FR2123278B1 (enExample) |
| GB (1) | GB1370904A (enExample) |
| HU (2) | HU162347B (enExample) |
| IE (2) | IE35937B1 (enExample) |
| LU (1) | LU64664A1 (enExample) |
| NL (2) | NL7117401A (enExample) |
| NO (2) | NO135891C (enExample) |
| SE (2) | SE391286B (enExample) |
| ZA (2) | ZA718326B (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4917894A (en) * | 1988-06-29 | 1990-04-17 | Beecham Inc. | Rapid-onset long-duration oral anesthetic composition |
| WO1998043619A2 (en) * | 1997-04-02 | 1998-10-08 | The Regents Of The University Of California | Method of local anesthesia |
| AU7389098A (en) * | 1997-05-16 | 1998-12-08 | Brigham And Women's Hospital | Local anesthetic formulations |
| RU2277097C1 (ru) * | 2004-12-27 | 2006-05-27 | Институт Молекулярной Генетики Российской Академии Наук (Имг Ран) | Высокомеченный тритием дигидрохлорид [3h]сакситоксина |
| US9018222B2 (en) | 2006-03-27 | 2015-04-28 | Wex Medical Limited | Use of sodium channel blockers for the treatment of neuropathic pain developing as a consequence of chemotherapy |
| US8957207B2 (en) | 2009-03-24 | 2015-02-17 | Proteus S.A. | Methods for producing phycotoxins |
| RS58750B1 (sr) | 2013-03-15 | 2019-06-28 | Childrens Medical Ct Corp | Kombinovane formulacije neosaksitoksina za produženu lokalnu anesteziju |
-
1971
- 1971-12-07 SE SE7115654A patent/SE391286B/xx unknown
- 1971-12-07 SE SE7115655A patent/SE391127B/xx unknown
- 1971-12-10 NO NO4557/71A patent/NO135891C/no unknown
- 1971-12-10 NO NO4558/71A patent/NO135892C/no unknown
- 1971-12-13 ZA ZA718326A patent/ZA718326B/xx unknown
- 1971-12-13 ZA ZA718327A patent/ZA718327B/xx unknown
- 1971-12-14 DK DK609571AA patent/DK130389B/da unknown
- 1971-12-16 HU HUAA688A patent/HU162347B/hu unknown
- 1971-12-16 BE BE776769A patent/BE776769A/xx unknown
- 1971-12-16 HU HU71AA689A patent/HU162185B/hu unknown
- 1971-12-16 BE BE776768A patent/BE776768A/xx unknown
- 1971-12-17 DK DK619971A patent/DK131606C/da active
- 1971-12-17 GB GB5865871A patent/GB1370904A/en not_active Expired
- 1971-12-17 AT AT1084871A patent/AT310938B/de not_active IP Right Cessation
- 1971-12-17 NL NL7117401A patent/NL7117401A/xx unknown
- 1971-12-17 DD DD159688A patent/DD96400A5/xx unknown
- 1971-12-17 CA CA130,377A patent/CA983850A/en not_active Expired
- 1971-12-17 AT AT1084971A patent/AT310939B/de not_active IP Right Cessation
- 1971-12-17 FR FR7145543A patent/FR2123278B1/fr not_active Expired
- 1971-12-17 FR FR7145542A patent/FR2123277B1/fr not_active Expired
- 1971-12-17 CA CA130,378A patent/CA986012A/en not_active Expired
- 1971-12-17 DD DD159910A patent/DD96144A5/xx unknown
- 1971-12-17 NL NL7117404A patent/NL7117404A/xx not_active Application Discontinuation
- 1971-12-18 DE DE19712163055 patent/DE2163055A1/de active Pending
- 1971-12-18 DE DE2163054A patent/DE2163054C3/de not_active Expired
- 1971-12-18 ES ES398109A patent/ES398109A1/es not_active Expired
- 1971-12-18 ES ES398108A patent/ES398108A1/es not_active Expired
- 1971-12-20 IE IE1611/71A patent/IE35937B1/xx unknown
- 1971-12-20 IE IE1610/71A patent/IE35910B1/xx unknown
- 1971-12-20 BR BR8428/71A patent/BR7108428D0/pt unknown
- 1971-12-20 BR BR8429/71A patent/BR7108429D0/pt unknown
- 1971-12-20 AU AU37100/71A patent/AU465875B2/en not_active Expired
-
1972
- 1972-01-26 LU LU64664D patent/LU64664A1/xx unknown
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