ES397370A1 - Procedimiento para la preparacion de un compuesto tranqui- lizante. - Google Patents
Procedimiento para la preparacion de un compuesto tranqui- lizante.Info
- Publication number
- ES397370A1 ES397370A1 ES397370A ES397370A ES397370A1 ES 397370 A1 ES397370 A1 ES 397370A1 ES 397370 A ES397370 A ES 397370A ES 397370 A ES397370 A ES 397370A ES 397370 A1 ES397370 A1 ES 397370A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- alpha
- carbon atoms
- fluorobutyrophenone
- hydroxybenzyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000005309 thioalkoxy group Chemical group 0.000 abstract 1
- 229940125725 tranquilizer Drugs 0.000 abstract 1
- 239000003204 tranquilizing agent Substances 0.000 abstract 1
- 230000002936 tranquilizing effect Effects 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9349570A | 1970-11-27 | 1970-11-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES397370A1 true ES397370A1 (es) | 1974-05-16 |
Family
ID=22239276
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES397370A Expired ES397370A1 (es) | 1970-11-27 | 1971-11-26 | Procedimiento para la preparacion de un compuesto tranqui- lizante. |
Country Status (16)
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE7409245L (enrdf_load_stackoverflow) * | 1973-07-19 | 1975-01-20 | Robins Co Inc A H | |
| US4246268A (en) * | 1979-02-09 | 1981-01-20 | Richardson-Merrell Inc. | Neuroleptic-4-(naphthylmethyl)piperidine derivatives |
| IE49998B1 (en) * | 1979-08-06 | 1986-01-22 | Merrell Dow Pharma | 4-(naphthalenyloxy)piperidine derivatives |
| US4284636A (en) * | 1979-09-04 | 1981-08-18 | Richardson-Merrell Inc. | Cinnamoylpiperidinobutyrophenone antipsychotic agents |
| US4283404A (en) * | 1979-09-04 | 1981-08-11 | Richardson-Merrell Inc. | Aroylethenylpiperidinobutyrophenone antipsychotic agents |
| ZA806501B (en) * | 1979-10-27 | 1981-10-28 | Richardson Merrell Inc | 4-(4-alkyl-aroyl-1-piperidino)butyrophenone antipsychotic agents |
| US4783471A (en) * | 1985-07-02 | 1988-11-08 | Merrell Dow Pharmaceuticals Inc. | N-aralkyl piperidine methanol derivatives and the uses thereof |
| CA1280421C (en) * | 1985-07-02 | 1991-02-19 | Albert A. Carr | 1,4-disubstituted piperidinyl derivatives |
| IL117149A0 (en) * | 1995-02-23 | 1996-06-18 | Schering Corp | Muscarinic antagonists |
| KR20070052319A (ko) * | 2004-09-13 | 2007-05-21 | 바이엘 크롭사이언스 아게 | Ｎ-(치환된 아릴메틸)-4-(이치환된 메틸)피페리딘 및중간체를 제조하는 방법 |
-
1971
- 1971-10-26 ZA ZA717147A patent/ZA717147B/xx unknown
- 1971-10-27 GB GB4994271A patent/GB1314955A/en not_active Expired
- 1971-10-27 IE IE1361/71A patent/IE35778B1/xx unknown
- 1971-10-29 CA CA126,448A patent/CA957376A/en not_active Expired
- 1971-11-04 IL IL38079A patent/IL38079A/xx unknown
- 1971-11-16 PH PH13014*UA patent/PH9306A/en unknown
- 1971-11-17 CH CH1670071A patent/CH562215A5/xx not_active IP Right Cessation
- 1971-11-18 JP JP9200371A patent/JPS5623985B2/ja not_active Expired
- 1971-11-19 BE BE775593A patent/BE775593A/xx not_active IP Right Cessation
- 1971-11-24 SE SE15032/71A patent/SE369900B/xx unknown
- 1971-11-24 NO NO4318/71A patent/NO135248C/no unknown
- 1971-11-24 DE DE2158136A patent/DE2158136C2/de not_active Expired
- 1971-11-25 NL NLAANVRAGE7116194,A patent/NL175411C/xx not_active IP Right Cessation
- 1971-11-26 FR FR7142529A patent/FR2115451B1/fr not_active Expired
- 1971-11-26 DK DK582171AA patent/DK135895B/da not_active IP Right Cessation
- 1971-11-26 ES ES397370A patent/ES397370A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| NO135248B (enrdf_load_stackoverflow) | 1976-11-29 |
| IE35778L (en) | 1972-05-27 |
| PH9306A (en) | 1975-08-18 |
| CH562215A5 (enrdf_load_stackoverflow) | 1975-05-30 |
| FR2115451A1 (enrdf_load_stackoverflow) | 1972-07-07 |
| NL175411C (nl) | 1984-11-01 |
| SE369900B (enrdf_load_stackoverflow) | 1974-09-23 |
| BE775593A (fr) | 1972-03-16 |
| NO135248C (enrdf_load_stackoverflow) | 1977-03-09 |
| GB1314955A (en) | 1973-04-26 |
| FR2115451B1 (enrdf_load_stackoverflow) | 1975-02-07 |
| NL175411B (nl) | 1984-06-01 |
| IE35778B1 (en) | 1976-05-26 |
| IL38079A (en) | 1974-10-22 |
| JPS5623985B2 (enrdf_load_stackoverflow) | 1981-06-03 |
| DE2158136C2 (de) | 1982-11-18 |
| NL7116194A (enrdf_load_stackoverflow) | 1972-05-30 |
| DK135895C (enrdf_load_stackoverflow) | 1977-12-12 |
| CA957376A (en) | 1974-11-05 |
| DK135895B (da) | 1977-07-11 |
| ZA717147B (en) | 1972-07-26 |
| IL38079A0 (en) | 1972-01-27 |
| DE2158136A1 (de) | 1972-05-31 |
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