ES392378A1 - Un procedimiento para la obtencion de un nuevo derivado farmaceuticamente activo del 2,3-diazobiciclo (5.4.0) unde- capentano. - Google Patents
Un procedimiento para la obtencion de un nuevo derivado farmaceuticamente activo del 2,3-diazobiciclo (5.4.0) unde- capentano.Info
- Publication number
- ES392378A1 ES392378A1 ES392378A ES392378A ES392378A1 ES 392378 A1 ES392378 A1 ES 392378A1 ES 392378 A ES392378 A ES 392378A ES 392378 A ES392378 A ES 392378A ES 392378 A1 ES392378 A1 ES 392378A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- dimethoxy
- acid
- compound
- hydrazine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- LGJQBONKYIQKQS-UHFFFAOYSA-N 3-cycloundeca-1,3,5,7,9-pentaen-1-yl-1,2-diazacycloundeca-2,5,7,9,11-pentaene Chemical class C1(=NN=CC=CC=CC=CC1)C1=CC=CC=CC=CC=CC1 LGJQBONKYIQKQS-UHFFFAOYSA-N 0.000 title 1
- OAKJQQAXSVQMHS-UHFFFAOYSA-N Hydrazine Chemical compound NN OAKJQQAXSVQMHS-UHFFFAOYSA-N 0.000 abstract 10
- 239000002253 acid Substances 0.000 abstract 7
- 150000001875 compounds Chemical class 0.000 abstract 7
- NWZSZGALRFJKBT-KNIFDHDWSA-N (2s)-2,6-diaminohexanoic acid;(2s)-2-hydroxybutanedioic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O.NCCCC[C@H](N)C(O)=O NWZSZGALRFJKBT-KNIFDHDWSA-N 0.000 abstract 5
- IKDUDTNKRLTJSI-UHFFFAOYSA-N hydrazine monohydrate Substances O.NN IKDUDTNKRLTJSI-UHFFFAOYSA-N 0.000 abstract 5
- 150000003839 salts Chemical class 0.000 abstract 5
- 238000006243 chemical reaction Methods 0.000 abstract 4
- -1 4,5-dimethoxy-phenyl Chemical group 0.000 abstract 3
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 2
- 230000021962 pH elevation Effects 0.000 abstract 2
- 150000001298 alcohols Chemical class 0.000 abstract 1
- 229950011260 betanaphthol Drugs 0.000 abstract 1
- 238000000354 decomposition reaction Methods 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000012452 mother liquor Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/72—Hydrazones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HUEE001861 | 1970-11-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES392378A1 true ES392378A1 (es) | 1973-09-16 |
Family
ID=10995350
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES392378A Expired ES392378A1 (es) | 1970-11-06 | 1971-06-17 | Un procedimiento para la obtencion de un nuevo derivado farmaceuticamente activo del 2,3-diazobiciclo (5.4.0) unde- capentano. |
Country Status (13)
| Country | Link |
|---|---|
| AT (2) | AT311982B (fa) |
| BE (1) | BE769080A (fa) |
| DE (1) | DE2122070A1 (fa) |
| ES (1) | ES392378A1 (fa) |
| GB (1) | GB1334271A (fa) |
| HK (1) | HK27776A (fa) |
| IL (1) | IL36777A0 (fa) |
| NL (1) | NL7108994A (fa) |
| PH (1) | PH9942A (fa) |
| PL (1) | PL71111B1 (fa) |
| SE (1) | SE368206B (fa) |
| YU (1) | YU40626B (fa) |
| ZA (1) | ZA712798B (fa) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU179018B (en) * | 1978-10-19 | 1982-08-28 | Gyogyszerkutato Intezet | Process for producing new 5h-2,3-benzodiazepine derivatives |
| AU1451900A (en) * | 1998-10-27 | 2000-05-15 | Vela Pharmaceuticals Inc. | Use of optically pure (r)-tofisopam for treating and preventing anxiety disorders and composition thereof |
| US6649607B2 (en) | 2001-05-18 | 2003-11-18 | Vela Pharmaceuticals, Inc. | Compositions and methods for treating or preventing convulsions or seizures |
| WO2003050092A2 (en) * | 2001-12-13 | 2003-06-19 | EGIS Gyógyszergyár Rt. | Process for the preparation of tofisopam and new intermediates |
| HU228212B1 (en) * | 2008-06-27 | 2013-02-28 | Egis Gyogyszergyar Nyrt | Process for the preparation of 1-(3,4-dimethoxy-phenyl)-5-ethyl-7,8-dimethoxy-4-methyl-5h-2,3-benzodiazepine with high purity |
-
1971
- 1971-04-30 ZA ZA712798A patent/ZA712798B/xx unknown
- 1971-05-03 PL PL1971147922A patent/PL71111B1/pl unknown
- 1971-05-03 SE SE05722/71A patent/SE368206B/xx unknown
- 1971-05-04 IL IL36777A patent/IL36777A0/xx unknown
- 1971-05-04 DE DE19712122070 patent/DE2122070A1/de active Pending
- 1971-05-05 AT AT869372A patent/AT311982B/de not_active IP Right Cessation
- 1971-05-05 YU YU1122/71A patent/YU40626B/xx unknown
- 1971-05-05 AT AT393871A patent/AT310171B/de not_active IP Right Cessation
- 1971-05-10 GB GB1404571*[A patent/GB1334271A/en not_active Expired
- 1971-06-17 ES ES392378A patent/ES392378A1/es not_active Expired
- 1971-06-25 BE BE769080A patent/BE769080A/xx not_active IP Right Cessation
- 1971-06-29 NL NL7108994A patent/NL7108994A/xx unknown
- 1971-10-29 PH PH12979A patent/PH9942A/en unknown
-
1976
- 1976-05-13 HK HK277/76*UA patent/HK27776A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HK27776A (en) | 1976-05-21 |
| PL71111B1 (fa) | 1974-04-30 |
| BE769080A (fr) | 1971-11-03 |
| DE2122070A1 (de) | 1972-06-08 |
| AT311982B (de) | 1973-12-10 |
| AT310171B (de) | 1973-09-25 |
| ZA712798B (en) | 1972-02-23 |
| PH9942A (en) | 1976-06-14 |
| YU40626B (en) | 1986-04-30 |
| SE368206B (fa) | 1974-06-24 |
| GB1334271A (en) | 1973-10-17 |
| IL36777A0 (en) | 1971-07-28 |
| NL7108994A (fa) | 1972-05-09 |
| YU112271A (en) | 1984-02-29 |
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