GB1334271A - Diazabicycloundecapentene derivative - Google Patents
Diazabicycloundecapentene derivativeInfo
- Publication number
- GB1334271A GB1334271A GB1404571*[A GB1404571A GB1334271A GB 1334271 A GB1334271 A GB 1334271A GB 1404571 A GB1404571 A GB 1404571A GB 1334271 A GB1334271 A GB 1334271A
- Authority
- GB
- United Kingdom
- Prior art keywords
- hydrazine
- acid
- reaction
- derivative
- hydrazine hydrate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/72—Hydrazones
Abstract
1334271 Diazabicycloundecapentane derivative E GY T GYOGYSZERVEGYESZETI GYAR 10 May 1971 [6 Nov 1970] 14045/71 Heading C2C The novel compound I and acid addition salts thereof are prepared (1) by reaction of compounds II with hydrazine or hydrazine hydrate to give compounds III and reacting compounds III with an acid, (2) by reaction of a 1-veratryl-3-methyl-4-ethyl- 6,7 - dimethoxy - isobenzopyrilium salt with hydrazine or hydrazine hydrate, followed by treatment with an acid or (3) by reaction of 3 - (2 - veratroyl - 4,5 - dimethoxyphenyl)- pentan-2-one with hydrazine or hydrazine hydrate in a mixture of one or more 1-4C alcohols and benzene to give an adduct IV which is then decomposed with an acid. Pharmaceutical compositions comprise a compound I together with a suitable excipient and are useful as tranquillizers.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HUEE001861 | 1970-11-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1334271A true GB1334271A (en) | 1973-10-17 |
Family
ID=10995350
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1404571*[A Expired GB1334271A (en) | 1970-11-06 | 1971-05-10 | Diazabicycloundecapentene derivative |
Country Status (13)
Country | Link |
---|---|
AT (2) | AT311982B (en) |
BE (1) | BE769080A (en) |
DE (1) | DE2122070A1 (en) |
ES (1) | ES392378A1 (en) |
GB (1) | GB1334271A (en) |
HK (1) | HK27776A (en) |
IL (1) | IL36777A0 (en) |
NL (1) | NL7108994A (en) |
PH (1) | PH9942A (en) |
PL (1) | PL71111B1 (en) |
SE (1) | SE368206B (en) |
YU (1) | YU40626B (en) |
ZA (1) | ZA712798B (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2439189A1 (en) * | 1978-10-19 | 1980-05-16 | Egyt Gyogyszervegyeszeti Gyar | NOVEL 5H-2,3-BENZODIAZEPINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
WO2009156776A1 (en) * | 2008-06-27 | 2009-12-30 | Egis Gyogyszergyar Nyilvanosan Müködö | Process for the preparation of high purity 1-(3,4-dimethoxy-phenyl)-5-ethyl-7,8-dimethoxy-4-methyl-5h-2,3-benzodiazepine |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2367748A (en) * | 1998-10-27 | 2002-04-17 | Vela Pharmaceuticals | Use of optically pure (R)- tofisopam for treating and preventing anxiety disorders and composition thereof |
US6649607B2 (en) | 2001-05-18 | 2003-11-18 | Vela Pharmaceuticals, Inc. | Compositions and methods for treating or preventing convulsions or seizures |
SK2792004A3 (en) * | 2001-12-13 | 2004-11-03 | Egyt Gyogyszervegyeszeti Gyar | Process for the preparation of tofisopam and new intermediates |
-
1971
- 1971-04-30 ZA ZA712798A patent/ZA712798B/en unknown
- 1971-05-03 PL PL1971147922A patent/PL71111B1/pl unknown
- 1971-05-03 SE SE05722/71A patent/SE368206B/xx unknown
- 1971-05-04 DE DE19712122070 patent/DE2122070A1/en active Pending
- 1971-05-04 IL IL36777A patent/IL36777A0/en unknown
- 1971-05-05 AT AT869372A patent/AT311982B/en not_active IP Right Cessation
- 1971-05-05 YU YU1122/71A patent/YU40626B/en unknown
- 1971-05-05 AT AT393871A patent/AT310171B/en not_active IP Right Cessation
- 1971-05-10 GB GB1404571*[A patent/GB1334271A/en not_active Expired
- 1971-06-17 ES ES392378A patent/ES392378A1/en not_active Expired
- 1971-06-25 BE BE769080A patent/BE769080A/en not_active IP Right Cessation
- 1971-06-29 NL NL7108994A patent/NL7108994A/xx unknown
- 1971-10-29 PH PH12979A patent/PH9942A/en unknown
-
1976
- 1976-05-13 HK HK277/76*UA patent/HK27776A/en unknown
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2439189A1 (en) * | 1978-10-19 | 1980-05-16 | Egyt Gyogyszervegyeszeti Gyar | NOVEL 5H-2,3-BENZODIAZEPINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
WO2009156776A1 (en) * | 2008-06-27 | 2009-12-30 | Egis Gyogyszergyar Nyilvanosan Müködö | Process for the preparation of high purity 1-(3,4-dimethoxy-phenyl)-5-ethyl-7,8-dimethoxy-4-methyl-5h-2,3-benzodiazepine |
Also Published As
Publication number | Publication date |
---|---|
SE368206B (en) | 1974-06-24 |
BE769080A (en) | 1971-11-03 |
ZA712798B (en) | 1972-02-23 |
YU112271A (en) | 1984-02-29 |
PH9942A (en) | 1976-06-14 |
DE2122070A1 (en) | 1972-06-08 |
AT310171B (en) | 1973-09-25 |
IL36777A0 (en) | 1971-07-28 |
YU40626B (en) | 1986-04-30 |
AT311982B (en) | 1973-12-10 |
ES392378A1 (en) | 1973-09-16 |
HK27776A (en) | 1976-05-21 |
PL71111B1 (en) | 1974-04-30 |
NL7108994A (en) | 1972-05-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed [section 19, patents act 1949] | ||
PE20 | Patent expired after termination of 20 years |