ES391701A1 - Un procedimiento para la preparacion de hepta y octapepti- dos. - Google Patents
Un procedimiento para la preparacion de hepta y octapepti- dos.Info
- Publication number
- ES391701A1 ES391701A1 ES71391701A ES391701A ES391701A1 ES 391701 A1 ES391701 A1 ES 391701A1 ES 71391701 A ES71391701 A ES 71391701A ES 391701 A ES391701 A ES 391701A ES 391701 A1 ES391701 A1 ES 391701A1
- Authority
- ES
- Spain
- Prior art keywords
- amino acid
- volyl
- prolyl
- blocked amino
- solvent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002904 solvent Substances 0.000 abstract 3
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 abstract 2
- 229940024606 amino acid Drugs 0.000 abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 2
- 230000000903 blocking effect Effects 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- ROHFNLRQFUQHCH-RXMQYKEDSA-N D-leucine Chemical compound CC(C)C[C@@H](N)C(O)=O ROHFNLRQFUQHCH-RXMQYKEDSA-N 0.000 abstract 1
- 229930182819 D-leucine Natural products 0.000 abstract 1
- 239000004471 Glycine Substances 0.000 abstract 1
- 125000003412 L-alanyl group Chemical group [H]N([H])[C@@](C([H])([H])[H])(C(=O)[*])[H] 0.000 abstract 1
- 125000000570 L-alpha-aspartyl group Chemical group [H]OC(=O)C([H])([H])[C@]([H])(N([H])[H])C(*)=O 0.000 abstract 1
- 125000000010 L-asparaginyl group Chemical group O=C([*])[C@](N([H])[H])([H])C([H])([H])C(=O)N([H])[H] 0.000 abstract 1
- AGPKZVBTJJNPAG-WHFBIAKZSA-N L-isoleucine Chemical compound CC[C@H](C)[C@H](N)C(O)=O AGPKZVBTJJNPAG-WHFBIAKZSA-N 0.000 abstract 1
- 229930182844 L-isoleucine Natural products 0.000 abstract 1
- 125000002842 L-seryl group Chemical group O=C([*])[C@](N([H])[H])([H])C([H])([H])O[H] 0.000 abstract 1
- 125000003580 L-valyl group Chemical group [H]N([H])[C@]([H])(C(=O)[*])C(C([H])([H])[H])(C([H])([H])[H])[H] 0.000 abstract 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 125000000539 amino acid group Chemical group 0.000 abstract 1
- 238000003776 cleavage reaction Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000003630 glycyl group Chemical group [H]N([H])C([H])([H])C(*)=O 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 229960000310 isoleucine Drugs 0.000 abstract 1
- 238000006386 neutralization reaction Methods 0.000 abstract 1
- -1 sarcosyl Chemical group 0.000 abstract 1
- 230000007017 scission Effects 0.000 abstract 1
- 125000002730 succinyl group Chemical group C(CCC(=O)*)(=O)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/14—Angiotensins: Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Vascular Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11504571A | 1971-02-12 | 1971-02-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES391701A1 true ES391701A1 (es) | 1973-06-16 |
Family
ID=22358997
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES71391701A Expired ES391701A1 (es) | 1971-02-12 | 1971-05-28 | Un procedimiento para la preparacion de hepta y octapepti- dos. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US3751404A (OSRAM) |
| JP (1) | JPS5414103B1 (OSRAM) |
| AT (1) | AT333986B (OSRAM) |
| DE (1) | DE2127393C3 (OSRAM) |
| ES (1) | ES391701A1 (OSRAM) |
| FR (1) | FR2125248B1 (OSRAM) |
| IL (1) | IL36869A (OSRAM) |
| PH (3) | PH13821A (OSRAM) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3907762A (en) * | 1971-12-27 | 1975-09-23 | Univ Sherbrooke | Angiotensin{hd II {B position 8 analogs |
| US4250086A (en) * | 1979-11-19 | 1981-02-10 | Ortho Pharmaceutical Corporation | Method and composition for preparation of H-SAR-LYS-SAR-GLN-NH2 |
| HU191961B (en) * | 1984-08-02 | 1987-04-28 | Richter Gedeon Vegyeszet | Process for producing 1,5 and 8 substituted peptides of angiotenzin-ii antagonistic activity |
| AU7034791A (en) * | 1989-12-29 | 1991-07-24 | University Technologies International Inc. | Methods for modelling tertiary structures of biologically active ligands including agonists and antagonists thereto and novel synthetic antagonists based on angiotensin |
| ZA9010460B (en) * | 1989-12-29 | 1992-11-25 | Univ Technologies Int | Methods for modelling tertiary structures of biologically active ligands including agonists and antagonists thereto and novel synthetic antagonists based on angiotensin |
| HUE026131T2 (en) | 2008-12-29 | 2016-05-30 | Trevena Inc | Beta-arresin effector and preparations and methods for their use |
| CA2938986A1 (en) | 2014-02-07 | 2015-08-13 | Trevena, Inc. | Crystalline and amorphous forms of a beta-arrestin effector |
| US9611293B2 (en) | 2014-05-19 | 2017-04-04 | Trevena, Inc. | Synthesis of beta-arrestin effectors |
| JP7026575B2 (ja) | 2018-05-22 | 2022-02-28 | 株式会社ニューフレアテクノロジー | 電子ビーム照射方法、電子ビーム照射装置、及びプログラム |
-
1971
- 1971-02-12 US US00115045A patent/US3751404A/en not_active Expired - Lifetime
- 1971-05-17 IL IL36869A patent/IL36869A/xx unknown
- 1971-05-21 PH PH12490A patent/PH13821A/en unknown
- 1971-05-28 ES ES71391701A patent/ES391701A1/es not_active Expired
- 1971-06-02 DE DE2127393A patent/DE2127393C3/de not_active Expired
- 1971-06-03 AT AT483471A patent/AT333986B/de not_active IP Right Cessation
- 1971-06-03 JP JP3832071A patent/JPS5414103B1/ja active Pending
- 1971-06-03 FR FR7120247A patent/FR2125248B1/fr not_active Expired
-
1975
- 1975-10-09 PH PH17650A patent/PH17092A/en unknown
-
1978
- 1978-02-27 PH PH20826A patent/PH17100A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US3751404A (en) | 1973-08-07 |
| FR2125248A1 (OSRAM) | 1972-09-29 |
| DE2127393B2 (de) | 1979-09-20 |
| IL36869A0 (en) | 1971-07-28 |
| PH17100A (en) | 1984-05-29 |
| JPS5414103B1 (OSRAM) | 1979-06-05 |
| ATA483471A (de) | 1976-04-15 |
| PH17092A (en) | 1984-05-29 |
| AT333986B (de) | 1976-12-27 |
| DE2127393A1 (de) | 1972-09-07 |
| IL36869A (en) | 1974-11-29 |
| FR2125248B1 (OSRAM) | 1975-08-01 |
| DE2127393C3 (de) | 1980-07-10 |
| PH13821A (en) | 1980-10-03 |
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