ES391533A1 - Procedimiento para la obtencion de penicilinas. - Google Patents
Procedimiento para la obtencion de penicilinas.Info
- Publication number
- ES391533A1 ES391533A1 ES391533A ES391533A ES391533A1 ES 391533 A1 ES391533 A1 ES 391533A1 ES 391533 A ES391533 A ES 391533A ES 391533 A ES391533 A ES 391533A ES 391533 A1 ES391533 A1 ES 391533A1
- Authority
- ES
- Spain
- Prior art keywords
- carbon atoms
- molecular weight
- low molecular
- alkyl
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 13
- 125000000217 alkyl group Chemical group 0.000 abstract 10
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- 239000001257 hydrogen Substances 0.000 abstract 5
- 125000003545 alkoxy group Chemical group 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 4
- 150000002431 hydrogen Chemical class 0.000 abstract 4
- 125000004423 acyloxy group Chemical group 0.000 abstract 3
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 3
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 2
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 2
- 125000003342 alkenyl group Chemical group 0.000 abstract 2
- 125000004397 aminosulfonyl group Chemical group NS(=O)(=O)* 0.000 abstract 2
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 2
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 2
- 229910052794 bromium Inorganic materials 0.000 abstract 2
- 125000001589 carboacyl group Chemical group 0.000 abstract 2
- 229910052801 chlorine Inorganic materials 0.000 abstract 2
- 239000000460 chlorine Substances 0.000 abstract 2
- 125000000392 cycloalkenyl group Chemical group 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 229910052731 fluorine Inorganic materials 0.000 abstract 2
- 239000011737 fluorine Substances 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 abstract 2
- 150000002825 nitriles Chemical class 0.000 abstract 2
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
- 239000002904 solvent Substances 0.000 abstract 2
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 abstract 2
- 229920002554 vinyl polymer Polymers 0.000 abstract 2
- NGHVIOIJCVXTGV-UHFFFAOYSA-N 6beta-amino-penicillanic acid Natural products OC(=O)C1C(C)(C)SC2C(N)C(=O)N21 NGHVIOIJCVXTGV-UHFFFAOYSA-N 0.000 abstract 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 229930182555 Penicillin Natural products 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 125000005236 alkanoylamino group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000003609 aryl vinyl group Chemical group 0.000 abstract 1
- 125000004104 aryloxy group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 150000001735 carboxylic acids Chemical class 0.000 abstract 1
- 125000000000 cycloalkoxy group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229910052740 iodine Inorganic materials 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 150000002960 penicillins Chemical class 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 125000004368 propenyl group Chemical group C(=CC)* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D261/18—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/46—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylureas
- C07C275/58—Y being a hetero atom
- C07C275/60—Y being an oxygen atom, e.g. allophanic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/30—Oxygen or sulfur atoms
- C07D233/32—One oxygen atom
- C07D233/38—One oxygen atom with acyl radicals or hetero atoms directly attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/10—Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Fodder In General (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2025415A DE2025415C3 (de) | 1970-05-25 | 1970-05-25 | Verfahren zur Herstellung von cyclischen Acylureido-Penicillinen |
| DE19712104579 DE2104579C3 (de) | 1971-02-01 | 1971-02-01 | Cyclische Acylureidopenicilline und sie enthaltende Arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES391533A1 true ES391533A1 (es) | 1974-08-01 |
Family
ID=25759180
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES391533A Expired ES391533A1 (es) | 1970-05-25 | 1971-05-25 | Procedimiento para la obtencion de penicilinas. |
| ES411676A Expired ES411676A1 (es) | 1970-05-25 | 1973-02-16 | Procedimiento para la obtencion de composiciones antibacte-riales. |
| ES411675A Expired ES411675A1 (es) | 1970-05-25 | 1973-02-16 | Procedimiento para la obtencion de composiciones antibacte-riales. |
| ES411674A Expired ES411674A1 (es) | 1970-05-25 | 1973-02-16 | Procedimiento para la obtencion de composiciones antibacte-riales. |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES411676A Expired ES411676A1 (es) | 1970-05-25 | 1973-02-16 | Procedimiento para la obtencion de composiciones antibacte-riales. |
| ES411675A Expired ES411675A1 (es) | 1970-05-25 | 1973-02-16 | Procedimiento para la obtencion de composiciones antibacte-riales. |
| ES411674A Expired ES411674A1 (es) | 1970-05-25 | 1973-02-16 | Procedimiento para la obtencion de composiciones antibacte-riales. |
Country Status (26)
| Country | Link |
|---|---|
| JP (1) | JPS55390B1 (en:Method) |
| AT (1) | AT306924B (en:Method) |
| BE (1) | BE767648A (en:Method) |
| BG (1) | BG23753A3 (en:Method) |
| CA (1) | CA932722A (en:Method) |
| CH (1) | CH571524A5 (en:Method) |
| CS (1) | CS185564B2 (en:Method) |
| CY (1) | CY830A (en:Method) |
| DD (1) | DD91496B3 (en:Method) |
| DK (1) | DK134438C (en:Method) |
| EG (1) | EG10490A (en:Method) |
| ES (4) | ES391533A1 (en:Method) |
| FI (1) | FI54485C (en:Method) |
| FR (1) | FR2100682B1 (en:Method) |
| GB (1) | GB1301962A (en:Method) |
| IE (1) | IE35404B1 (en:Method) |
| IL (1) | IL36904A (en:Method) |
| KE (1) | KE2591A (en:Method) |
| LU (1) | LU63204A1 (en:Method) |
| NL (1) | NL172659C (en:Method) |
| NO (1) | NO141759C (en:Method) |
| PH (1) | PH12110A (en:Method) |
| RO (1) | RO59290A (en:Method) |
| SE (1) | SE395895B (en:Method) |
| SU (1) | SU420181A3 (en:Method) |
| YU (1) | YU35889B (en:Method) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2260118C2 (de) * | 1972-12-08 | 1982-06-03 | Bayer Ag, 5090 Leverkusen | Penicilline sowie ihre Verwendung als Arzneimittel |
| DE2354219A1 (de) * | 1973-10-30 | 1975-05-07 | Bayer Ag | Beta-lactam-antibiotica, ein verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
| US4039673A (en) | 1973-10-30 | 1977-08-02 | Bayer Aktiengesellschaft | Penicillins and cephalosporins and their production |
| GB1486349A (en) * | 1974-11-28 | 1977-09-21 | Bayer Ag | Beta-lactam antibiotics process for their preparation and their use as medicaments |
| GB1584400A (en) * | 1976-12-24 | 1981-02-11 | Bayer Ag | (2-oxo-imidazoliden-1-yl(carbonylamino)-acetamido-cephalosporins and penicillins |
| KR860000300B1 (ko) * | 1983-12-19 | 1986-03-31 | 보령제약 주식회사 | 아실우레이도 페니실린 유도체의 제조방법 |
-
1971
- 1971-04-23 CH CH599171A patent/CH571524A5/xx not_active IP Right Cessation
- 1971-05-18 BG BG017581A patent/BG23753A3/xx unknown
- 1971-05-19 EG EG212/71A patent/EG10490A/xx active
- 1971-05-19 CS CS7100003647A patent/CS185564B2/cs unknown
- 1971-05-20 SU SU1660129A patent/SU420181A3/ru active
- 1971-05-21 FI FI1402/71A patent/FI54485C/fi active
- 1971-05-21 LU LU63204D patent/LU63204A1/xx unknown
- 1971-05-21 IE IE644/71A patent/IE35404B1/xx unknown
- 1971-05-24 PH PH12494A patent/PH12110A/en unknown
- 1971-05-24 IL IL7136904A patent/IL36904A/xx unknown
- 1971-05-24 YU YU1296/71A patent/YU35889B/xx unknown
- 1971-05-24 DK DK251171A patent/DK134438C/da not_active IP Right Cessation
- 1971-05-24 SE SE7106668A patent/SE395895B/xx unknown
- 1971-05-24 NO NO1946/71A patent/NO141759C/no unknown
- 1971-05-24 DD DD71155308A patent/DD91496B3/de unknown
- 1971-05-25 JP JP3524571A patent/JPS55390B1/ja active Pending
- 1971-05-25 BE BE767648A patent/BE767648A/xx not_active IP Right Cessation
- 1971-05-25 CY CY830A patent/CY830A/xx unknown
- 1971-05-25 GB GB1688171A patent/GB1301962A/en not_active Expired
- 1971-05-25 AT AT450571A patent/AT306924B/de not_active IP Right Cessation
- 1971-05-25 NL NLAANVRAGE7107176,A patent/NL172659C/xx not_active IP Right Cessation
- 1971-05-25 ES ES391533A patent/ES391533A1/es not_active Expired
- 1971-05-25 CA CA113785A patent/CA932722A/en not_active Expired
- 1971-05-25 FR FR7118933A patent/FR2100682B1/fr not_active Expired
- 1971-05-25 RO RO67015A patent/RO59290A/ro unknown
-
1973
- 1973-02-16 ES ES411676A patent/ES411676A1/es not_active Expired
- 1973-02-16 ES ES411675A patent/ES411675A1/es not_active Expired
- 1973-02-16 ES ES411674A patent/ES411674A1/es not_active Expired
-
1975
- 1975-12-22 KE KE2591*UA patent/KE2591A/xx unknown
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