ES388909A1 - N-vinyl-quinolones - Google Patents
N-vinyl-quinolonesInfo
- Publication number
- ES388909A1 ES388909A1 ES388909A ES388909A ES388909A1 ES 388909 A1 ES388909 A1 ES 388909A1 ES 388909 A ES388909 A ES 388909A ES 388909 A ES388909 A ES 388909A ES 388909 A1 ES388909 A1 ES 388909A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- hydrogen
- quinolones
- see formula
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/16—Ring systems of three rings containing carbocyclic rings other than six-membered
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Procedure for the preparation of new N-vinylquinolones of the general formula ** (See formula) ** wherein one of the radicals R1 and R2 represents a hydrogen atom and the other together with means a 1,3-propylene radical, R4 represents a hydrogen atom or a lower alcohol group and Y represents a hydroxyl, lower alkoxy or optionally substituted amino, as well as its pharmacologically safe salts, characterized in that: a) allyl quinolones of formula II are transposed ** (See formula) ** in which R1, R2, R3 and Y have the meanings indicated above and R5 means hydrogen or a lower alcohol group, which has a carbon atom less than R4, with strong bases, eventually at elevated temperature; or b) quinolones of formula III are condensed, with separation of Z and hydrogen from the amine ** (See formula) ** in which R1, R2, R3 and Y have the meanings indicated above, with compounds of formula IV ** (See formula) ** wherein R4 has the above meaning and X and Z represent reactive radicals or else together an oxygen or sulfur atom, and then X and one of the hydrogen atoms are removed in position α, after which it eventually becomes and subsequently in a manner known per se, and/or compounds I are transformed into their pharmacologically compatible salts. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2011885A DE2011885C3 (en) | 1970-03-13 | 1970-03-13 | 1,4-Dihydro-3-carboxy-cyclopentano (h) -quinolone- (4) -derivatives, process for the preparation thereof and their use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES388909A1 true ES388909A1 (en) | 1973-05-01 |
Family
ID=5764939
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES388909A Expired ES388909A1 (en) | 1970-03-13 | 1971-03-04 | N-vinyl-quinolones |
Country Status (20)
| Country | Link |
|---|---|
| JP (1) | JPS4835268B2 (en) |
| AT (2) | AT303734B (en) |
| BG (2) | BG18415A3 (en) |
| CA (1) | CA944355A (en) |
| CH (2) | CH558359A (en) |
| CS (2) | CS161899B2 (en) |
| DE (1) | DE2011885C3 (en) |
| DK (1) | DK129839B (en) |
| ES (1) | ES388909A1 (en) |
| FI (1) | FI49501C (en) |
| FR (1) | FR2085701B1 (en) |
| GB (1) | GB1282076A (en) |
| IE (1) | IE35111B1 (en) |
| IL (1) | IL36397A (en) |
| NL (1) | NL145854B (en) |
| PL (1) | PL82724B1 (en) |
| RO (2) | RO58367A (en) |
| SE (1) | SE361313B (en) |
| SU (2) | SU434653A3 (en) |
| ZA (1) | ZA711607B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3988460A (en) * | 1972-05-10 | 1976-10-26 | Boehringer Mannheim G.M.B.H. | Cyclopentenoquinolone compounds for treating bacterial infections |
| JPS50114345U (en) * | 1974-02-28 | 1975-09-18 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB830832A (en) * | 1957-02-15 | 1960-03-23 | Ici Ltd | New quinolones and therapeutic compositions containing them |
| CA944354A (en) * | 1968-07-23 | 1974-03-26 | Boehringer Mannheim G.M.B.H. | Cycloalkano-quinolone derivatives |
-
1970
- 1970-03-13 DE DE2011885A patent/DE2011885C3/en not_active Expired
-
1971
- 1971-02-08 SU SU1618801A patent/SU434653A3/en active
- 1971-02-08 SU SU1747931A patent/SU436493A3/ru active
- 1971-03-04 BG BG16969A patent/BG18415A3/xx unknown
- 1971-03-04 ES ES388909A patent/ES388909A1/en not_active Expired
- 1971-03-04 BG BG18790A patent/BG18416A3/xx unknown
- 1971-03-10 DK DK112171AA patent/DK129839B/en unknown
- 1971-03-10 CH CH550674A patent/CH558359A/en not_active IP Right Cessation
- 1971-03-10 CH CH352771A patent/CH558358A/en not_active IP Right Cessation
- 1971-03-11 RO RO66229A patent/RO58367A/ro unknown
- 1971-03-11 NL NL717103247A patent/NL145854B/en unknown
- 1971-03-11 CS CS1805A patent/CS161899B2/cs unknown
- 1971-03-11 CS CS5256*A patent/CS161900B2/cs unknown
- 1971-03-11 IL IL36397A patent/IL36397A/en unknown
- 1971-03-11 RO RO68915A patent/RO58563A/ro unknown
- 1971-03-11 ZA ZA711607A patent/ZA711607B/en unknown
- 1971-03-12 FR FR7108638A patent/FR2085701B1/fr not_active Expired
- 1971-03-12 AT AT218371A patent/AT303734B/en not_active IP Right Cessation
- 1971-03-12 SE SE03194/71A patent/SE361313B/xx unknown
- 1971-03-12 CA CA107,660A patent/CA944355A/en not_active Expired
- 1971-03-12 AT AT00541/72A patent/AT303735B/en not_active IP Right Cessation
- 1971-03-12 FI FI710732A patent/FI49501C/en active
- 1971-03-12 IE IE308/71A patent/IE35111B1/en unknown
- 1971-03-12 PL PL1971146843A patent/PL82724B1/en unknown
- 1971-03-13 JP JP46014018A patent/JPS4835268B2/ja not_active Expired
- 1971-04-19 GB GB23663/71A patent/GB1282076A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| CH558359A (en) | 1975-01-31 |
| RO58367A (en) | 1975-09-15 |
| DK129839B (en) | 1974-11-25 |
| AT303734B (en) | 1972-12-11 |
| BG18416A3 (en) | 1974-10-25 |
| IL36397A (en) | 1974-10-22 |
| SU436493A3 (en) | 1974-07-15 |
| FR2085701B1 (en) | 1975-08-01 |
| CH558358A (en) | 1975-01-31 |
| NL7103247A (en) | 1971-09-15 |
| IE35111L (en) | 1971-09-13 |
| FI49501C (en) | 1975-07-10 |
| PL82724B1 (en) | 1975-10-31 |
| SU434653A3 (en) | 1974-06-30 |
| DE2011885B2 (en) | 1980-08-07 |
| DK129839C (en) | 1975-05-05 |
| BG18415A3 (en) | 1974-10-25 |
| AT303735B (en) | 1972-11-15 |
| IE35111B1 (en) | 1975-11-12 |
| RO58563A (en) | 1975-09-15 |
| DE2011885A1 (en) | 1971-09-30 |
| FI49501B (en) | 1975-04-01 |
| CS161900B2 (en) | 1975-06-10 |
| CA944355A (en) | 1974-03-26 |
| IL36397A0 (en) | 1971-05-26 |
| JPS4835268B2 (en) | 1973-10-26 |
| GB1282076A (en) | 1972-07-19 |
| CS161899B2 (en) | 1975-06-10 |
| JPS462928A (en) | 1971-10-22 |
| NL145854B (en) | 1975-05-15 |
| SE361313B (en) | 1973-10-29 |
| DE2011885C3 (en) | 1981-05-21 |
| FR2085701A1 (en) | 1971-12-31 |
| ZA711607B (en) | 1971-12-29 |
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