ES388093A1 - Procedimiento de preparacion de sulfuros ciclicos condensa-dos. - Google Patents
Procedimiento de preparacion de sulfuros ciclicos condensa-dos.Info
- Publication number
- ES388093A1 ES388093A1 ES388093A ES388093A ES388093A1 ES 388093 A1 ES388093 A1 ES 388093A1 ES 388093 A ES388093 A ES 388093A ES 388093 A ES388093 A ES 388093A ES 388093 A1 ES388093 A1 ES 388093A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- condensed cyclic
- see formula
- thiochroman
- acetic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- JGAJZLHGTFUIAA-UHFFFAOYSA-N 2-(3,4-dihydro-2h-thiochromen-6-yl)acetic acid Chemical class S1CCCC2=CC(CC(=O)O)=CC=C21 JGAJZLHGTFUIAA-UHFFFAOYSA-N 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 3
- YNAVUWVOSKDBBP-UHFFFAOYSA-N Morpholine Chemical compound C1COCCN1 YNAVUWVOSKDBBP-UHFFFAOYSA-N 0.000 abstract 2
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 2
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- UCKMPCXJQFINFW-UHFFFAOYSA-N Sulphide Chemical compound [S-2] UCKMPCXJQFINFW-UHFFFAOYSA-N 0.000 abstract 1
- 238000005672 Willgerodt-Kindler rearrangement reaction Methods 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- -1 cyclic sulfides Chemical class 0.000 abstract 1
- AEOCXXJPGCBFJA-UHFFFAOYSA-N ethionamide Chemical compound CCC1=CC(C(N)=S)=CC=N1 AEOCXXJPGCBFJA-UHFFFAOYSA-N 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical compound [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
- C07D337/02—Seven-membered rings
- C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D337/08—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with one six-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR707004619A FR2077733B1 (enExample) | 1970-02-10 | 1970-02-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES388093A1 true ES388093A1 (es) | 1973-05-01 |
Family
ID=9050355
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES388093A Expired ES388093A1 (es) | 1970-02-10 | 1971-02-09 | Procedimiento de preparacion de sulfuros ciclicos condensa-dos. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US3714190A (enExample) |
| BE (1) | BE762636A (enExample) |
| CH (1) | CH538499A (enExample) |
| DE (1) | DE2106045A1 (enExample) |
| ES (1) | ES388093A1 (enExample) |
| FR (1) | FR2077733B1 (enExample) |
| GB (1) | GB1322988A (enExample) |
| NL (1) | NL7101735A (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2341022A1 (de) * | 1973-08-14 | 1975-02-27 | Hoechst Ag | Schaedlingsbekaempfungsmittel |
| US4229575A (en) * | 1978-02-27 | 1980-10-21 | Richardson-Merrell Inc. | 7-(2,3-Dihydrobenzo-5-furanyl)-acetamido cephalosporin derivatives |
| FI842738A7 (fi) * | 1983-07-14 | 1985-01-15 | Syntex Inc | Aroyylibentsofuraani- ja bentsotiofeenietikka- ja propionihapot. |
| EP0389425B1 (de) * | 1989-03-22 | 1995-04-26 | Ciba-Geigy Ag | Neue Benzothiopyranylamine |
| US6642268B2 (en) | 1994-09-13 | 2003-11-04 | G.D. Searle & Co. | Combination therapy employing ileal bile acid transport inhibiting benzothipines and HMG Co-A reductase inhibitors |
| US6107494A (en) * | 1994-09-13 | 2000-08-22 | G.D. Searle And Company | Substituted 5-aryl-benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake |
| US6268392B1 (en) | 1994-09-13 | 2001-07-31 | G. D. Searle & Co. | Combination therapy employing ileal bile acid transport inhibiting benzothiepines and HMG Co-A reductase inhibitors |
| US6262277B1 (en) | 1994-09-13 | 2001-07-17 | G.D. Searle And Company | Intermediates and processes for the preparation of benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake |
| DE69911058T2 (de) * | 1998-12-23 | 2004-06-03 | G.D. Searle Llc, Chicago | Kombinationen einem ibat inhibitor und einem mtp inhibitor für kardiovaskuläre indikationen |
| BR9916484A (pt) * | 1998-12-23 | 2002-01-22 | Searle Llc | Combinações de inibidores do transporte de ácido biliar ileal e de agentes sequestrantes de ácido biliar em indicações cardiovasculares |
| CZ20012341A3 (cs) * | 1998-12-23 | 2001-12-12 | G. D. Searle Llc Corparate Patent Department | Kombinace inhibitorů transferoního proteinu cholesterylesterů a derivátů kyseliny fibrové pro kardiovaskulární indikace |
| PT1140188E (pt) * | 1998-12-23 | 2003-10-31 | Searle Llc | Combinacoes de inibidores do transporte de acidos biliares do ileo e de inibidores da proteina de transferencia de esteres de colesterilo para doencas cardiovasculares. |
| WO2000038722A1 (en) | 1998-12-23 | 2000-07-06 | G.D. Searle & Co. | COMBINATIONS OF CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS AND HMG CoA REDUCTASE INHIBITORS FOR CARDIOVASCULAR INDICATIONS |
| ATE242007T1 (de) | 1998-12-23 | 2003-06-15 | Searle Llc | Kombinationen von cholesteryl ester transfer protein inhibitoren und nicotinsäure derivaten für kardiovaskuläre indikationen |
| EP1340510A1 (en) | 1998-12-23 | 2003-09-03 | G.D. Searle LLC. | Combinations of cholesteryl ester transfer protein inhibitors and bile acid sequestering agents for cardiovascular indications |
| HK1045114A1 (zh) | 1998-12-23 | 2002-11-15 | G‧D‧瑟尔有限公司 | 适用於心血管疾病的回肠胆汁酸转运抑制剂和贝酸衍生物的组合 |
| WO2001068096A2 (en) * | 2000-03-10 | 2001-09-20 | Pharmacia Corporation | Combination therapy for the prophylaxis and treatment of hyperlipidemic conditions and disorders |
| AU2001240115A1 (en) | 2000-03-10 | 2001-09-24 | Pharmacia Corporation | Method for the preparation of tetrahydrobenzothiepines |
| US20040077625A1 (en) * | 2001-07-25 | 2004-04-22 | Tremont Samuel J. | Novel 1,4-benzothiazepine and 1,5-benzothiazepine compounds as inhibitors of apical sodium codependent bile acid transport abd taurocholate uptake |
| CA2464685A1 (en) * | 2001-11-02 | 2003-05-15 | G.D. Searle Llc | Novel mono- and di-fluorinated benzothiepine compounds as inhibitors of apical sodium co-dependent bile acid transport (asbt) and taurocholate uptake |
| AU2003207431A1 (en) | 2002-01-17 | 2003-09-02 | Pharmacia Corporation | Novel alkyl/aryl hydroxy or keto thiepines. |
-
1970
- 1970-02-10 FR FR707004619A patent/FR2077733B1/fr not_active Expired
-
1971
- 1971-02-03 US US00112407A patent/US3714190A/en not_active Expired - Lifetime
- 1971-02-05 CH CH174071A patent/CH538499A/fr not_active IP Right Cessation
- 1971-02-08 BE BE762636A patent/BE762636A/xx unknown
- 1971-02-09 DE DE19712106045 patent/DE2106045A1/de active Pending
- 1971-02-09 ES ES388093A patent/ES388093A1/es not_active Expired
- 1971-02-10 NL NL7101735A patent/NL7101735A/xx unknown
- 1971-04-19 GB GB2144171A patent/GB1322988A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| NL7101735A (enExample) | 1971-08-12 |
| US3714190A (en) | 1973-01-30 |
| FR2077733A1 (enExample) | 1971-11-05 |
| FR2077733B1 (enExample) | 1973-03-16 |
| CH538499A (fr) | 1973-06-30 |
| DE2106045A1 (de) | 1971-09-02 |
| GB1322988A (en) | 1973-07-11 |
| BE762636A (fr) | 1971-08-09 |
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