ES388093A1 - Procedimiento de preparacion de sulfuros ciclicos condensa-dos. - Google Patents
Procedimiento de preparacion de sulfuros ciclicos condensa-dos.Info
- Publication number
- ES388093A1 ES388093A1 ES388093A ES388093A ES388093A1 ES 388093 A1 ES388093 A1 ES 388093A1 ES 388093 A ES388093 A ES 388093A ES 388093 A ES388093 A ES 388093A ES 388093 A1 ES388093 A1 ES 388093A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- condensed cyclic
- see formula
- thiochroman
- acetic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- JGAJZLHGTFUIAA-UHFFFAOYSA-N 2-(3,4-dihydro-2h-thiochromen-6-yl)acetic acid Chemical class S1CCCC2=CC(CC(=O)O)=CC=C21 JGAJZLHGTFUIAA-UHFFFAOYSA-N 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 3
- YNAVUWVOSKDBBP-UHFFFAOYSA-N Morpholine Chemical compound C1COCCN1 YNAVUWVOSKDBBP-UHFFFAOYSA-N 0.000 abstract 2
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 2
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- UCKMPCXJQFINFW-UHFFFAOYSA-N Sulphide Chemical compound [S-2] UCKMPCXJQFINFW-UHFFFAOYSA-N 0.000 abstract 1
- 238000005672 Willgerodt-Kindler rearrangement reaction Methods 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- -1 cyclic sulfides Chemical class 0.000 abstract 1
- AEOCXXJPGCBFJA-UHFFFAOYSA-N ethionamide Chemical compound CCC1=CC(C(N)=S)=CC=N1 AEOCXXJPGCBFJA-UHFFFAOYSA-N 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical compound [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
- C07D337/02—Seven-membered rings
- C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D337/08—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with one six-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR707004619A FR2077733B1 (enExample) | 1970-02-10 | 1970-02-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES388093A1 true ES388093A1 (es) | 1973-05-01 |
Family
ID=9050355
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES388093A Expired ES388093A1 (es) | 1970-02-10 | 1971-02-09 | Procedimiento de preparacion de sulfuros ciclicos condensa-dos. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US3714190A (enExample) |
| BE (1) | BE762636A (enExample) |
| CH (1) | CH538499A (enExample) |
| DE (1) | DE2106045A1 (enExample) |
| ES (1) | ES388093A1 (enExample) |
| FR (1) | FR2077733B1 (enExample) |
| GB (1) | GB1322988A (enExample) |
| NL (1) | NL7101735A (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2341022A1 (de) * | 1973-08-14 | 1975-02-27 | Hoechst Ag | Schaedlingsbekaempfungsmittel |
| US4229575A (en) * | 1978-02-27 | 1980-10-21 | Richardson-Merrell Inc. | 7-(2,3-Dihydrobenzo-5-furanyl)-acetamido cephalosporin derivatives |
| FI842738A7 (fi) * | 1983-07-14 | 1985-01-15 | Syntex Inc | Aroyylibentsofuraani- ja bentsotiofeenietikka- ja propionihapot. |
| DE69018864D1 (de) * | 1989-03-22 | 1995-06-01 | Ciba Geigy Ag | Neue Benzothiopyranylamine. |
| US6642268B2 (en) | 1994-09-13 | 2003-11-04 | G.D. Searle & Co. | Combination therapy employing ileal bile acid transport inhibiting benzothipines and HMG Co-A reductase inhibitors |
| US6268392B1 (en) | 1994-09-13 | 2001-07-31 | G. D. Searle & Co. | Combination therapy employing ileal bile acid transport inhibiting benzothiepines and HMG Co-A reductase inhibitors |
| US6262277B1 (en) * | 1994-09-13 | 2001-07-17 | G.D. Searle And Company | Intermediates and processes for the preparation of benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake |
| US6107494A (en) * | 1994-09-13 | 2000-08-22 | G.D. Searle And Company | Substituted 5-aryl-benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake |
| PT1140190E (pt) * | 1998-12-23 | 2003-02-28 | Searle Llc | Combinacoes de inibidores do transporte ileal dos acidos biliares e agentes sequestrantes dos acidos biliares usadas para problemas cardiovasculares |
| DE69908645T2 (de) * | 1998-12-23 | 2004-05-13 | G.D. Searle Llc, Chicago | Kombinationen von cholesteryl ester transfer protein inhibitoren und fibronsäure derivaten für kardiovaskuläre indikationen |
| EP1140185B1 (en) | 1998-12-23 | 2003-06-04 | G.D. Searle LLC. | Combinations of cholesteryl ester transfer protein inhibitors and bile acid sequestering agents for cardiovascular indications |
| JP2002533413A (ja) * | 1998-12-23 | 2002-10-08 | ジー．ディー．サール エルエルシー | 心臓血管に適用するための回腸胆汁酸輸送阻害剤およびフィブリン酸誘導体の組み合わせ |
| WO2000038722A1 (en) | 1998-12-23 | 2000-07-06 | G.D. Searle & Co. | COMBINATIONS OF CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS AND HMG CoA REDUCTASE INHIBITORS FOR CARDIOVASCULAR INDICATIONS |
| EP1342475A1 (en) | 1998-12-23 | 2003-09-10 | G.D. Searle LLC. | Combinations of ileal bile acid transport inhibitors and cholesteryl ester transfer protein inhibitors for cardiovascular indications |
| DE69911058T2 (de) * | 1998-12-23 | 2004-06-03 | G.D. Searle Llc, Chicago | Kombinationen einem ibat inhibitor und einem mtp inhibitor für kardiovaskuläre indikationen |
| JP2002533408A (ja) | 1998-12-23 | 2002-10-08 | ジー．ディー．サール エルエルシー | 心臓血管に適用するためのコレステリルエステル転送タンパク質阻害剤およびニコチン酸誘導体の組み合わせ |
| US6794544B2 (en) | 2000-03-10 | 2004-09-21 | Pharmacia Corporation | Method for the preparation of tetrahydrobenzothiepines |
| WO2001068096A2 (en) * | 2000-03-10 | 2001-09-20 | Pharmacia Corporation | Combination therapy for the prophylaxis and treatment of hyperlipidemic conditions and disorders |
| US20040077625A1 (en) * | 2001-07-25 | 2004-04-22 | Tremont Samuel J. | Novel 1,4-benzothiazepine and 1,5-benzothiazepine compounds as inhibitors of apical sodium codependent bile acid transport abd taurocholate uptake |
| MXPA04003524A (es) * | 2001-11-02 | 2004-07-23 | Searle Llc | Compuestos de benzotiepina monofluorados y difluorados novedosos como inhibidores de transporte de acido biliar co-dependiente de sodio apical (asbt) y captacion de taurocolato. |
| BR0306643A (pt) | 2002-01-17 | 2004-10-19 | Pharmacia Corp | Novos compostos de hidroxi alquil/aril ou ceto tiepina como inibidores do transporte co-dependente de ácido biliar-sódio apical |
-
1970
- 1970-02-10 FR FR707004619A patent/FR2077733B1/fr not_active Expired
-
1971
- 1971-02-03 US US00112407A patent/US3714190A/en not_active Expired - Lifetime
- 1971-02-05 CH CH174071A patent/CH538499A/fr not_active IP Right Cessation
- 1971-02-08 BE BE762636A patent/BE762636A/xx unknown
- 1971-02-09 ES ES388093A patent/ES388093A1/es not_active Expired
- 1971-02-09 DE DE19712106045 patent/DE2106045A1/de active Pending
- 1971-02-10 NL NL7101735A patent/NL7101735A/xx unknown
- 1971-04-19 GB GB2144171A patent/GB1322988A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE2106045A1 (de) | 1971-09-02 |
| CH538499A (fr) | 1973-06-30 |
| GB1322988A (en) | 1973-07-11 |
| NL7101735A (enExample) | 1971-08-12 |
| US3714190A (en) | 1973-01-30 |
| FR2077733A1 (enExample) | 1971-11-05 |
| BE762636A (fr) | 1971-08-09 |
| FR2077733B1 (enExample) | 1973-03-16 |
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