ES386402A1 - Un procedimiento de preparacion de compuestos de imidazo y pirimido-(2,1-b)quinazolina. - Google Patents

Un procedimiento de preparacion de compuestos de imidazo y pirimido-(2,1-b)quinazolina.

Info

Publication number
ES386402A1
ES386402A1 ES386402A ES386402A ES386402A1 ES 386402 A1 ES386402 A1 ES 386402A1 ES 386402 A ES386402 A ES 386402A ES 386402 A ES386402 A ES 386402A ES 386402 A1 ES386402 A1 ES 386402A1
Authority
ES
Spain
Prior art keywords
prepared
reacting
alkanoyl
alkyl
isatin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES386402A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Smith Kline and French Laboratories Ltd
Original Assignee
Smith Kline and French Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline and French Laboratories Ltd filed Critical Smith Kline and French Laboratories Ltd
Publication of ES386402A1 publication Critical patent/ES386402A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/24—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in positions 2 and 4
    • C07D265/26—Two oxygen atoms, e.g. isatoic anhydride
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/38—Oxygen atoms in positions 2 and 3, e.g. isatin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES386402A 1969-12-18 1970-12-12 Un procedimiento de preparacion de compuestos de imidazo y pirimido-(2,1-b)quinazolina. Expired ES386402A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US88637069A 1969-12-18 1969-12-18

Publications (1)

Publication Number Publication Date
ES386402A1 true ES386402A1 (es) 1973-03-16

Family

ID=25388927

Family Applications (1)

Application Number Title Priority Date Filing Date
ES386402A Expired ES386402A1 (es) 1969-12-18 1970-12-12 Un procedimiento de preparacion de compuestos de imidazo y pirimido-(2,1-b)quinazolina.

Country Status (14)

Country Link
US (1) US3621025A (en, 2012)
JP (1) JPS4932879B1 (en, 2012)
BE (1) BE760013A (en, 2012)
CH (1) CH565795A5 (en, 2012)
DE (1) DE2062024A1 (en, 2012)
ES (1) ES386402A1 (en, 2012)
FR (1) FR2081375B1 (en, 2012)
GB (1) GB1273897A (en, 2012)
HU (1) HU163940B (en, 2012)
LU (1) LU62240A1 (en, 2012)
NL (1) NL7018335A (en, 2012)
NO (1) NO129745B (en, 2012)
SE (1) SE363638B (en, 2012)
ZA (1) ZA707817B (en, 2012)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3887559A (en) * 1971-07-15 1975-06-03 Sandoz Ag Pharmacologically active tricyclic quinazolinones
US3875161A (en) * 1971-07-15 1975-04-01 Sandoz Ag Imidazo(2,1-b)quinazolin-5(1OH)-ones
US3905976A (en) * 1971-11-24 1975-09-16 Sandoz Ag Substituted tricyclic quinazolinones
USRE31617E (en) * 1972-02-04 1984-06-26 Bristol-Myers Company Optionally substituted 1,2,3,5-tetrahydroimidezo(2,1-b)-quinazolin-2-ones and 6(H)-1,2,3,4-tetrahydropyimido(2,1-b)quinazolin-2-ones
BE794964A (fr) * 1972-02-04 1973-08-02 Bristol Myers Co Nouveaux agents hypotenseurs et procede pour les preparer
US3932407A (en) * 1973-11-19 1976-01-13 Bristol-Myers Company Optionally substituted 1,2,3,5-tetrahydroimidezo(2,1-b)-quinazolin-2-ones and 6(H)-1,2,3,4-tetrahydropyimido(2,1-b)quinazolin-2-ones
SE407408B (sv) * 1972-09-22 1979-03-26 Bristol Myers Co Forfarande for framstellning av kondenserade kinozolinderivat
US3875160A (en) * 1973-01-22 1975-04-01 Goetz E Hardtmann Quaternary-tricyclic quinazolinones
US3984556A (en) * 1973-01-19 1976-10-05 Sandoz, Inc. Alkyl-substituted-tricyclic quinazolinones for lowering blood pressure
US3894022A (en) * 1973-06-25 1975-07-08 Sandoz Ag Tetracyclic quinazolinones and quinazolinium salts
JPS5752352B2 (en, 2012) * 1974-02-28 1982-11-06
US3983120A (en) * 1974-11-06 1976-09-28 Bristol-Myers Company Process for the preparation of optionally substituted 1,2,3,5-tetrahydroimidazo[2,1-b]quinazolin-2-ones
US3983119A (en) * 1974-11-06 1976-09-28 Bristol-Myers Company Process for the preparation of optionally substituted 1,2,3,5-tetrahydroimidazo[2,1-b]quinazolin-2-ones
JPS5448797A (en) * 1977-09-06 1979-04-17 Sumitomo Chem Co Ltd Tricyclic condensed pyrimidine derivative and its preparation
EP0029559A3 (en) * 1979-11-24 1981-09-30 Sandoz Ag 5,10-dihydroimidazo(2,1-b)quinazolines, their production and pharmaceutical compositions containing them
PH17745A (en) * 1981-09-16 1984-11-27 Sandoz Ag Trifluoromethyl substituted tricyclic quinazolinones
US4452787A (en) * 1981-09-16 1984-06-05 Sandoz, Inc. 1-Substituted tricyclic quinazolinones having biological activity as tranquilizers
US4760065A (en) * 1986-02-13 1988-07-26 Hardtmann Goetz E Trifluoromethyl substituted tetracyclic quinazolin-ones having tranquilizing activity

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3257401A (en) * 1964-06-18 1966-06-21 Searle & Co 5-hydroxy-2-methylcycloalkyl[d] imidazo[1, 2-a]pyrimidines

Also Published As

Publication number Publication date
FR2081375A1 (en, 2012) 1971-12-03
ZA707817B (en) 1971-08-25
BE760013A (fr) 1971-06-08
NO129745B (en, 2012) 1974-05-20
LU62240A1 (en, 2012) 1971-07-27
DE2062024A1 (de) 1972-05-25
JPS4932879B1 (en, 2012) 1974-09-03
US3621025A (en) 1971-11-16
FR2081375B1 (en, 2012) 1974-08-23
HU163940B (en, 2012) 1973-11-28
SE363638B (en, 2012) 1974-01-28
CH565795A5 (en, 2012) 1975-08-29
NL7018335A (en, 2012) 1971-06-22
GB1273897A (en) 1972-05-10

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