ES384311A1 - 1-carbamoyl-4-phenylpiperidines and tetrahydropyridines - Google Patents

1-carbamoyl-4-phenylpiperidines and tetrahydropyridines

Info

Publication number
ES384311A1
ES384311A1 ES384311A ES384311A ES384311A1 ES 384311 A1 ES384311 A1 ES 384311A1 ES 384311 A ES384311 A ES 384311A ES 384311 A ES384311 A ES 384311A ES 384311 A1 ES384311 A1 ES 384311A1
Authority
ES
Spain
Prior art keywords
carbamoyl
tetrahydropyridines
trifluoromethylphenyl
formula
phenylpiperidines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES384311A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AH Robins Co Inc
Original Assignee
AH Robins Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AH Robins Co Inc filed Critical AH Robins Co Inc
Publication of ES384311A1 publication Critical patent/ES384311A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/02—Preparation by ring-closure or hydrogenation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

A process for the preparation of 1-carbamoyl-4-phenylpiperidines and 1-carbamoyl-4-tetrahydropyridines selected from the group having the formula: **(See formula)** wherein R1 is selected from the group consisting of hydrogen, lower alkyl having from one to four carbon atoms, phenyl, lower alkylphenyl, lower alkoxyphenyl, trifluoromethylphenyl and halogenophenyl; R2 is trifluoromethyl; m is zero and one, and when m is zero, the dotted line is a double bond, which involves mixing and reacting a compound of the formula: **(See formula)** where R2 and m have the values assigned above, with nitrourea and isocyanates to produce 1-carbamoyl-4 (m- and p-trifluoromethylphenyl) -piperidine, and 1-carbamoyl-4 (m- and p-trifluoromethylphenyl) -1,2, 3,6-tetrahydropyridines. (Machine-translation by Google Translate, not legally binding)
ES384311A 1969-10-27 1970-10-07 1-carbamoyl-4-phenylpiperidines and tetrahydropyridines Expired ES384311A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US86988169A 1969-10-27 1969-10-27

Publications (1)

Publication Number Publication Date
ES384311A1 true ES384311A1 (en) 1973-09-01

Family

ID=25354406

Family Applications (1)

Application Number Title Priority Date Filing Date
ES384311A Expired ES384311A1 (en) 1969-10-27 1970-10-07 1-carbamoyl-4-phenylpiperidines and tetrahydropyridines

Country Status (14)

Country Link
JP (1) JPS4939266B1 (en)
AT (1) AT302354B (en)
BE (1) BE757436A (en)
CA (1) CA918161A (en)
CH (1) CH525886A (en)
DE (1) DE2048589A1 (en)
ES (1) ES384311A1 (en)
FR (1) FR2070167B1 (en)
GB (1) GB1307277A (en)
NL (1) NL7015396A (en)
NO (1) NO131172C (en)
PH (1) PH9289A (en)
SE (2) SE372942B (en)
ZA (1) ZA707307B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4374991A (en) 1976-12-17 1983-02-22 Rohm And Haas Company 2,6-Dimethylpiperidinyl-N-carbobutoxymethyl urea
US4357471A (en) 1976-12-17 1982-11-02 Rohm And Haas Company Azaspiro compounds
US4400512A (en) * 1976-12-17 1983-08-23 Rohm And Haas Company Azaspiro compounds
US4405630A (en) * 1980-12-29 1983-09-20 Rohm And Haas Company Arthropod repellent compositions and methods
FR2501506A1 (en) * 1981-03-11 1982-09-17 Sanofi Sa PHARMACEUTICAL COMPOSITIONS WITH ANOREXIGENIC ACTION CONTAINING TETRAHYDROPYRIDINE DERIVATIVES
ATE431822T1 (en) * 2003-07-24 2009-06-15 Euro Celtique Sa HETEROARYL TETRAHYDROPIPERIDYL COMPOUNDS SUITABLE FOR THE TREATMENT OR PREVENTION OF PAIN

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1087174A (en) * 1965-04-05 1967-10-11 Allen & Hanburys Ltd Piperidine derivatives
FR1589754A (en) * 1968-10-17 1970-04-06

Also Published As

Publication number Publication date
BE757436A (en) 1971-03-16
CA918161A (en) 1973-01-02
NO131172C (en) 1975-04-16
SE372942B (en) 1975-01-20
CH525886A (en) 1972-07-31
FR2070167B1 (en) 1975-03-14
PH9289A (en) 1975-08-13
AT302354B (en) 1972-10-10
FR2070167A1 (en) 1971-09-10
ZA707307B (en) 1971-07-28
JPS4939266B1 (en) 1974-10-24
NL7015396A (en) 1971-04-29
SE382454B (en) 1976-02-02
NO131172B (en) 1975-01-06
GB1307277A (en) 1973-02-14
DE2048589A1 (en) 1971-05-06

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