GB1321329A - Piperidine process and intermediates therefor - Google Patents

Piperidine process and intermediates therefor

Info

Publication number
GB1321329A
GB1321329A GB4436271A GB4436271A GB1321329A GB 1321329 A GB1321329 A GB 1321329A GB 4436271 A GB4436271 A GB 4436271A GB 4436271 A GB4436271 A GB 4436271A GB 1321329 A GB1321329 A GB 1321329A
Authority
GB
United Kingdom
Prior art keywords
formula
prepared
compounds
intermediates
formulae
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4436271A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teikoku Chemical Industry Co Ltd
Original Assignee
Teikoku Chemical Industry Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP3720271A external-priority patent/JPS5029471B1/ja
Priority claimed from JP3720371A external-priority patent/JPS5029472B1/ja
Priority claimed from JP6430271A external-priority patent/JPS4829786A/ja
Application filed by Teikoku Chemical Industry Co Ltd filed Critical Teikoku Chemical Industry Co Ltd
Publication of GB1321329A publication Critical patent/GB1321329A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/52—Oxygen atoms attached in position 4 having an aryl radical as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

1321329 Piperidine derivatives TEIKOKU CHEMICAL INDUSTRY CO Ltd 23 Sept 1971 [25 Sept 1970 30 May 1971 (2) 23 Aug 1971] 44362/71 Heading C2C Compounds of Formula I are prepared by action of a base on novel compounds of Formula II in which formulae R is H or OH and Ar and Ar<SP>1</SP> are each phenyl optionally substituted for example, by C 1 -C 8 alkyl, halogen or C 1 -C 8 alkoxy substituents, and n is 2, 3 or 4, which are prepared by reaction of a compound of Formula IV wherein X is a reactive acid residue with a compound of Formula III given below. Intermediates of Formula III are prepared as in the reaction scheme wherein R<SP>1</SP> is C 1 -C 8 alkyl and R<SP>11</SP> is H, C 1 -C 8 olkoxy or C 1 -C 8 alkanoyloxy. Intermediates of Formula IV above wherein R = OH are prepared as a reaction scheme in which formulae Y is H, -(CH 2 ) n-1 OH or -(CH 2 ) n-1 X and those wherein R is H are prepared by reduction of the compounds of Formula XVI given in the above scheme. The compounds of Formula I are used in pharmaceutical compositions.
GB4436271A 1970-09-25 1971-09-23 Piperidine process and intermediates therefor Expired GB1321329A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP8385470 1970-09-25
JP3720271A JPS5029471B1 (en) 1971-05-30 1971-05-30
JP3720371A JPS5029472B1 (en) 1971-05-30 1971-05-30
JP6430271A JPS4829786A (en) 1971-08-23 1971-08-23

Publications (1)

Publication Number Publication Date
GB1321329A true GB1321329A (en) 1973-06-27

Family

ID=27460377

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4436271A Expired GB1321329A (en) 1970-09-25 1971-09-23 Piperidine process and intermediates therefor

Country Status (2)

Country Link
CA (1) CA978191A (en)
GB (1) GB1321329A (en)

Also Published As

Publication number Publication date
CA978191A (en) 1975-11-18

Similar Documents

Publication Publication Date Title
GB1394732A (en) Enamine compounds their manufacture and use
GB1390748A (en) Alkyl and cycloalkylthiophenylalkylaminoalkanols their salts and the preparation thereof
ES431054A1 (en) N-{8 (Methoxymethyl-furyl)-methyl{9 -morphinans or -6,7-benzomorphans and salts thereof
GB1348093A (en) Dialkyl-4-hydroxyphenylcarboxylates of tris-hydroxyalkyl-iso cyanurate
ES444804A1 (en) Process for preparing (1-acylaminomethyl)-1,2,3,4-tetrahydroisoquinolines
GB1159340A (en) Thion- and Thiol-Carbamate Derivatives
GB1335946A (en) 4- w-coumarin-7-yloxy- alkyl- piperazine derivatives
GB1436533A (en) Aryl piperazine derivatives of adenine
GB1321329A (en) Piperidine process and intermediates therefor
GB1477957A (en) Heterocyclic substituted styrenes and their use as optical brighteners
GB1368568A (en) 3,5-dialkyl-4-hydroxyphenyl alkanoic acid ester of 2,4,6-tris hydroxyethylamino of derivatives of triazine
GB1316587A (en) 4-chloropyrazolyl compounds and their use as brightening agents
GB1414452A (en) Process for the manufacture of cyclohexadienes
GB1396240A (en) Derivatives of 2-hydroxybenzophenone and their use as stabilisers
ES444369A1 (en) Dienic derivatives of the androstane series and process
GB1349358A (en) Hydrogenation process
GB1132597A (en) Benzazepine derivatives
GB1301367A (en)
GB1048903A (en) Piperazines and process for their manufacture
GB1432736A (en) Substituted 2-pyrones and process for their preparation
GB1352089A (en) Bis-styryltriazoles their use for the optical brightening of organic materials and processes for their manufacture
GB1327647A (en) Tetrahydroisoquinoline derivatives
GB1322919A (en) Manufacture of 3-acyl-or 3-alkoxycarbonyl-5,6-dihydro-4h-pyrans
GB1358082A (en) Enamine ketones and their production
GB1430188A (en) Diaza-oxa-bicyclodecane derivatives

Legal Events

Date Code Title Description
PS Patent sealed
PLNP Patent lapsed through nonpayment of renewal fees