ES381705A1 - Thiophen ethers and processes for preparing them - Google Patents
Thiophen ethers and processes for preparing themInfo
- Publication number
- ES381705A1 ES381705A1 ES381705A ES381705A ES381705A1 ES 381705 A1 ES381705 A1 ES 381705A1 ES 381705 A ES381705 A ES 381705A ES 381705 A ES381705 A ES 381705A ES 381705 A1 ES381705 A1 ES 381705A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- compounds
- reacted
- groups
- see formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
-
- H—ELECTRICITY
- H02—GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
- H02B—BOARDS, SUBSTATIONS OR SWITCHING ARRANGEMENTS FOR THE SUPPLY OR DISTRIBUTION OF ELECTRIC POWER
- H02B5/00—Non-enclosed substations; Substations with enclosed and non-enclosed equipment
- H02B5/01—Earthing arrangements, e.g. earthing rods
Abstract
Procedure for the preparation of thiophene ethers of the general formula I ** (See formula) ** wherein R1 represents a thiophene ring that may optionally be substituted by low molecular weight alcohol groups, hydroxymethyl groups, carboxyl groups, which may also be esterified, chlorine or bromine atoms, as well as by a combination of these groups; R2 means a phenyl radical optionally substituted by low molecular weight alcohol or alkoxy groups, chlorine or bromine atoms, which may also contain 1 or 2 ring nitrogen atoms, and A means a straight or branched chain alcohol radical. with 2 to 6 carbon atoms, or a propylene radical that can carry a hydroxy group on the central carbon atom, as well as its acid addition salts, characterized in that a) compounds of formula II are reacted R1-O-A-X (II) wherein X represents a halogen atom or a hydroxysulfonyloxy, alcohol-sulfoniloxy or arylsulfonyloxy group, with compounds of formula III ** (See formula) ** or b) compounds of formula IV are reacted ** (See formula) ** preferably in the form of their alkaline or alkaline earth salts with compounds of formula V ** (See formula) ** or c) compounds of formula VI are reacted: ** (See formula) ** with compounds of formula III ** (See formula) ** or d) compounds of formula VII are reacted R1-O-A-NH2 (VII) with compounds of formula VIII ** (See formula) ** preferably in the form of their esters capable of reacting; or e) compounds of formula IX are reacted ** (See formula) ** preferably in the form of its esters capable of reacting with a compound of formula X H2N-R2 (X) or f) are reduced with compound metal hydrides of formula XI ** (See formula) ** where B is a straight or branched chain alcohol radical with 1 to 5 carbon atoms; or g) compounds of formula XII are reacted R1-O-A-NH-CH2-CH2-NH-R2 (XII) with esters capable of reacting ethylene glycol and, optionally, in the obtained compounds, carboxylic acid ester groups present are saponified, carboxylic acids are decarboxylated, carboxylic acid ester groups are reduced, bases thus obtained are transformed into their salts by addition of acid or are transformed you go out on the free bases. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19691935558 DE1935558A1 (en) | 1969-07-12 | 1969-07-12 | Tiophenaethers and methods for their preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES381705A1 true ES381705A1 (en) | 1972-12-01 |
Family
ID=5739692
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES381705A Expired ES381705A1 (en) | 1969-07-12 | 1970-07-11 | Thiophen ethers and processes for preparing them |
Country Status (12)
| Country | Link |
|---|---|
| AT (4) | AT310734B (en) |
| AU (1) | AU1748370A (en) |
| BE (1) | BE753376A (en) |
| BR (1) | BR6915358D0 (en) |
| DE (1) | DE1935558A1 (en) |
| ES (1) | ES381705A1 (en) |
| FR (1) | FR2059509B1 (en) |
| GB (1) | GB1278348A (en) |
| IE (1) | IE34381B1 (en) |
| IL (1) | IL34868A0 (en) |
| NL (1) | NL7010021A (en) |
| ZA (1) | ZA704737B (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2209557A1 (en) * | 1972-12-12 | 1974-07-05 | Roussel Uclaf | Piperazo alkyl thiazolyl ketones/ethers - adrenolytics and antihypertensives prepd. from a piperazine and a halo alkyl thiazole |
| DE2310215A1 (en) * | 1973-03-01 | 1974-09-12 | Albert Ag Chem Werke | NEW THIOPHEN DERIVATIVES AND PROCESS FOR THEIR PRODUCTION |
| FR2464952A1 (en) * | 1979-09-13 | 1981-03-20 | Roussel Uclaf | Thienyl derivatives prepd. from 1,2-epoxy 3-(3-(thienyloxy)) propane - and an amine, used as medicament e.g. for treating arterial hypertension |
| DE2950064A1 (en) * | 1979-12-13 | 1981-06-19 | Basf Ag, 6700 Ludwigshafen | PIPERIDE DERIVATIVES OF 3-HYDROXYTHIOPHEN-2-CARBONIC ACIDS AND ESTERS, THEIR PRODUCTION AND THE PHARMACEUTICAL PREPARATIONS CONTAINING THEM |
| JPS62178585A (en) * | 1986-01-29 | 1987-08-05 | レフオ−サン−ゲゼルシヤフト エム・ベ−・ハ− | 1-(3-(2-hydroxy-3-alkylaminopropoxy)-2-thienyl)-3-phenyl-1- propanone and its acid addition salt, its production and pharmacological composition containing the same |
| US7083928B2 (en) * | 2001-04-05 | 2006-08-01 | Infectio Diagnostic (I.D.I.), Inc. | Detection of negatively charged polymers using water-soluble, cationic, polythiophene derivatives |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1458905A (en) * | 1959-03-26 | 1966-04-29 | Process for the preparation of 1-aralkyl-4-arylpiperazines |
-
1969
- 1969-07-12 DE DE19691935558 patent/DE1935558A1/en active Pending
- 1969-12-19 BR BR215358/69A patent/BR6915358D0/en unknown
-
1970
- 1970-07-07 NL NL7010021A patent/NL7010021A/xx unknown
- 1970-07-08 IL IL34868A patent/IL34868A0/en unknown
- 1970-07-08 ZA ZA704737A patent/ZA704737B/en unknown
- 1970-07-10 AT AT291672A patent/AT310734B/en not_active IP Right Cessation
- 1970-07-10 AT AT291472A patent/AT310732B/en not_active IP Right Cessation
- 1970-07-10 IE IE900/70A patent/IE34381B1/en unknown
- 1970-07-10 AT AT291572A patent/AT310733B/en not_active IP Right Cessation
- 1970-07-10 AT AT630070A patent/AT305999B/en not_active IP Right Cessation
- 1970-07-11 ES ES381705A patent/ES381705A1/en not_active Expired
- 1970-07-13 BE BE753376A patent/BE753376A/en unknown
- 1970-07-13 GB GB33832/70A patent/GB1278348A/en not_active Expired
- 1970-07-13 AU AU17483/70A patent/AU1748370A/en not_active Expired
- 1970-07-15 FR FR7025993A patent/FR2059509B1/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE1935558A1 (en) | 1971-01-28 |
| IE34381L (en) | 1971-01-12 |
| AT305999B (en) | 1973-03-26 |
| AT310732B (en) | 1973-10-10 |
| NL7010021A (en) | 1971-01-14 |
| IE34381B1 (en) | 1975-04-30 |
| AT310733B (en) | 1973-10-10 |
| FR2059509B1 (en) | 1973-12-21 |
| AT310734B (en) | 1973-10-10 |
| GB1278348A (en) | 1972-06-21 |
| ZA704737B (en) | 1971-12-29 |
| FR2059509A1 (en) | 1971-06-04 |
| BE753376A (en) | 1971-01-13 |
| BR6915358D0 (en) | 1973-01-25 |
| AU1748370A (en) | 1972-01-20 |
| IL34868A0 (en) | 1970-09-17 |
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