IE34381L - Thiophen ethers - Google Patents

Thiophen ethers

Info

Publication number
IE34381L
IE34381L IE700900A IE90070A IE34381L IE 34381 L IE34381 L IE 34381L IE 700900 A IE700900 A IE 700900A IE 90070 A IE90070 A IE 90070A IE 34381 L IE34381 L IE 34381L
Authority
IE
Ireland
Prior art keywords
thiophen
ethers
salts
bromine
july
Prior art date
Application number
IE700900A
Other versions
IE34381B1 (en
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of IE34381L publication Critical patent/IE34381L/en
Publication of IE34381B1 publication Critical patent/IE34381B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • H—ELECTRICITY
    • H02—GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
    • H02B—BOARDS, SUBSTATIONS OR SWITCHING ARRANGEMENTS FOR THE SUPPLY OR DISTRIBUTION OF ELECTRIC POWER
    • H02B5/00—Non-enclosed substations; Substations with enclosed and non-enclosed equipment
    • H02B5/01—Earthing arrangements, e.g. earthing rods

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Power Engineering (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cosmetics (AREA)

Abstract

1278348 Thiophen ethers FARBWERKE HOECHST AG 13 July 1970 [12 July 1969] 33832/70 Heading C2C Novel thiophen ethers of the general Formula I wherein R 1 represents a thiophen ring optionally substituted by one or more C 1-6 alkyl, hydroxymethyl, carboxyl (optionally esterified) groups or chlorine or bromine or a combination thereof; R 2 is a phenyl, pyridyl, pyridazinyl, pyrimidinyl or pyrazinyl group optionally substituted by one or more C 1-6 alkyl or alkoxy or chlorine or bromine and A is a C 2 -C 6 straight or branched alkylene radical or a CH 2 CHOH-CH 2 group may be prepared by one of six known condensation reactions, or reduction of a keto group in a corresponding compound to Formula I having an R 1 -O-B-CO- side chain, wherein B is a C 1 -C 5 straight or branched alkylene radical with a metal hydride to produce A, followed optionally by saponification, decarboxylation reducing carboxylic acid ester groups and/or converting the bases into salts or salts into free bases. The intermediate VI may be prepared by condensation of a hydroxy thiophen with chlorohydrin in the presence of base. Pharmaceutical compositions of the compounds I or their pharmaceutically acceptable salts show α-sympathicolytic activity and have sedative, blood pressure lowering and vasodilatatory effects when administered parenterally or orally. [GB1278348A]
IE900/70A 1969-07-12 1970-07-10 Thiophen ethers and processes for preparing them IE34381B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19691935558 DE1935558A1 (en) 1969-07-12 1969-07-12 Tiophenaethers and methods for their preparation

Publications (2)

Publication Number Publication Date
IE34381L true IE34381L (en) 1971-01-12
IE34381B1 IE34381B1 (en) 1975-04-30

Family

ID=5739692

Family Applications (1)

Application Number Title Priority Date Filing Date
IE900/70A IE34381B1 (en) 1969-07-12 1970-07-10 Thiophen ethers and processes for preparing them

Country Status (12)

Country Link
AT (4) AT305999B (en)
AU (1) AU1748370A (en)
BE (1) BE753376A (en)
BR (1) BR6915358D0 (en)
DE (1) DE1935558A1 (en)
ES (1) ES381705A1 (en)
FR (1) FR2059509B1 (en)
GB (1) GB1278348A (en)
IE (1) IE34381B1 (en)
IL (1) IL34868A0 (en)
NL (1) NL7010021A (en)
ZA (1) ZA704737B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2209557A1 (en) * 1972-12-12 1974-07-05 Roussel Uclaf Piperazo alkyl thiazolyl ketones/ethers - adrenolytics and antihypertensives prepd. from a piperazine and a halo alkyl thiazole
DE2310215A1 (en) * 1973-03-01 1974-09-12 Albert Ag Chem Werke NEW THIOPHEN DERIVATIVES AND PROCESS FOR THEIR PRODUCTION
FR2464952A1 (en) * 1979-09-13 1981-03-20 Roussel Uclaf Thienyl derivatives prepd. from 1,2-epoxy 3-(3-(thienyloxy)) propane - and an amine, used as medicament e.g. for treating arterial hypertension
DE2950064A1 (en) * 1979-12-13 1981-06-19 Basf Ag, 6700 Ludwigshafen PIPERIDE DERIVATIVES OF 3-HYDROXYTHIOPHEN-2-CARBONIC ACIDS AND ESTERS, THEIR PRODUCTION AND THE PHARMACEUTICAL PREPARATIONS CONTAINING THEM
JPS62178585A (en) * 1986-01-29 1987-08-05 レフオ−サン−ゲゼルシヤフト　エム・ベ−・ハ− 1-(3-(2-hydroxy-3-alkylaminopropoxy)-2-thienyl)-3-phenyl-1- propanone and its acid addition salt, its production and pharmacological composition containing the same
CA2442860C (en) * 2001-04-05 2011-02-01 Mario Leclerc Detection of negatively charged polymers using water-soluble, cationic, polythiophene derivatives

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1458905A (en) * 1959-03-26 1966-04-29 Process for the preparation of 1-aralkyl-4-arylpiperazines

Also Published As

Publication number Publication date
AT310732B (en) 1973-10-10
ZA704737B (en) 1971-12-29
AT310734B (en) 1973-10-10
DE1935558A1 (en) 1971-01-28
FR2059509A1 (en) 1971-06-04
IL34868A0 (en) 1970-09-17
AU1748370A (en) 1972-01-20
AT310733B (en) 1973-10-10
NL7010021A (en) 1971-01-14
ES381705A1 (en) 1972-12-01
AT305999B (en) 1973-03-26
GB1278348A (en) 1972-06-21
IE34381B1 (en) 1975-04-30
FR2059509B1 (en) 1973-12-21
BR6915358D0 (en) 1973-01-25
BE753376A (en) 1971-01-13

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