ES375495A1 - Procedimiento para la preparacion de vetonas derivadas de la 1-(2-hidroxi-etil) piperazina. - Google Patents
Procedimiento para la preparacion de vetonas derivadas de la 1-(2-hidroxi-etil) piperazina.Info
- Publication number
- ES375495A1 ES375495A1 ES375495A ES375495A ES375495A1 ES 375495 A1 ES375495 A1 ES 375495A1 ES 375495 A ES375495 A ES 375495A ES 375495 A ES375495 A ES 375495A ES 375495 A1 ES375495 A1 ES 375495A1
- Authority
- ES
- Spain
- Prior art keywords
- pharmaceutically acceptable
- piperazine
- hydroxyethyl
- formula
- halogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000002576 ketones Chemical class 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- BGJSXRVXTHVRSN-UHFFFAOYSA-N 1,3,5-trioxane Chemical group C1OCOCO1 BGJSXRVXTHVRSN-UHFFFAOYSA-N 0.000 abstract 1
- WFCSWCVEJLETKA-UHFFFAOYSA-N 2-piperazin-1-ylethanol Chemical compound OCCN1CCNCC1 WFCSWCVEJLETKA-UHFFFAOYSA-N 0.000 abstract 1
- LSQARZALBDFYQZ-UHFFFAOYSA-N 4,4'-difluorobenzophenone Chemical compound C1=CC(F)=CC=C1C(=O)C1=CC=C(F)C=C1 LSQARZALBDFYQZ-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 1
- XHFGWHUWQXTGAT-UHFFFAOYSA-N dimethylamine hydrochloride Natural products CNC(C)C XHFGWHUWQXTGAT-UHFFFAOYSA-N 0.000 abstract 1
- IQDGSYLLQPDQDV-UHFFFAOYSA-N dimethylazanium;chloride Chemical compound Cl.CNC IQDGSYLLQPDQDV-UHFFFAOYSA-N 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229910052740 iodine Inorganic materials 0.000 abstract 1
- 239000003176 neuroleptic agent Substances 0.000 abstract 1
- 230000000701 neuroleptic effect Effects 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR6900630A FR2028047B1 (enrdf_load_stackoverflow) | 1969-01-16 | 1969-01-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES375495A1 true ES375495A1 (es) | 1972-05-16 |
Family
ID=9027881
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES375495A Expired ES375495A1 (es) | 1969-01-16 | 1970-01-16 | Procedimiento para la preparacion de vetonas derivadas de la 1-(2-hidroxi-etil) piperazina. |
Country Status (5)
| Country | Link |
|---|---|
| BE (1) | BE743969A (enrdf_load_stackoverflow) |
| DE (1) | DE2001144A1 (enrdf_load_stackoverflow) |
| ES (1) | ES375495A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2028047B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1261004A (enrdf_load_stackoverflow) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2145682C3 (de) * | 1971-09-13 | 1975-09-04 | Kali-Chemie Ag, 3000 Hannover | 1,4-disubstituierte Piperazin-Derivate und deren Säureadditionsverbindungen |
| FR2206088A1 (en) * | 1972-11-14 | 1974-06-07 | Synthelabo | Analgesic piperazino butyrophenone ketals - prepd. by reaction of halo butyrophenone ketal with hydroxy alkyl piperazine |
| WO2006074192A2 (en) * | 2005-01-03 | 2006-07-13 | Bionaut Pharmaceuticals, Inc. | Treatment of inflammatory disorders |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1481001A (fr) * | 1959-07-01 | 1967-05-19 | Procédé de préparation des dérivés de la phénacyl-pipérazine |
-
1969
- 1969-01-16 FR FR6900630A patent/FR2028047B1/fr not_active Expired
- 1969-12-31 BE BE743969D patent/BE743969A/xx unknown
-
1970
- 1970-01-12 DE DE19702001144 patent/DE2001144A1/de active Pending
- 1970-01-15 GB GB211070A patent/GB1261004A/en not_active Expired
- 1970-01-16 ES ES375495A patent/ES375495A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| BE743969A (enrdf_load_stackoverflow) | 1970-05-28 |
| GB1261004A (en) | 1972-01-19 |
| FR2028047A1 (enrdf_load_stackoverflow) | 1970-10-09 |
| FR2028047B1 (enrdf_load_stackoverflow) | 1974-10-11 |
| DE2001144A1 (de) | 1970-07-23 |
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