ES374947A1 - A procedure for the preparation of derivatives of N-substitute symmetrical dihydrotriazine. (Machine-translation by Google Translate, not legally binding) - Google Patents

A procedure for the preparation of derivatives of N-substitute symmetrical dihydrotriazine. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES374947A1
ES374947A1 ES374947A ES374947A ES374947A1 ES 374947 A1 ES374947 A1 ES 374947A1 ES 374947 A ES374947 A ES 374947A ES 374947 A ES374947 A ES 374947A ES 374947 A1 ES374947 A1 ES 374947A1
Authority
ES
Spain
Prior art keywords
dihydrotriazine
symmetrical
unsubstituted
derivatives
lower alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES374947A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of ES374947A1 publication Critical patent/ES374947A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/10—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • E—FIXED CONSTRUCTIONS
    • E04—BUILDING
    • E04D—ROOF COVERINGS; SKY-LIGHTS; GUTTERS; ROOF-WORKING TOOLS
    • E04D13/00—Special arrangements or devices in connection with roof coverings; Protection against birds; Roof drainage; Sky-lights
    • E04D13/15—Trimming strips; Edge strips; Fascias; Expansion joints for roofs
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

A pharmaceutical antimicrobial composition. comprising an N-substituted symmetrical dihydrotriazine derivative where R 1 is an aromatic ring system, a heterocyclic group or a non-aryl C 3 -C 8 carbocyclic ring system, all of which may be substituted or unsubstituted, R 2 is a substituted or unsubstituted divalent C 2 -C 16 aliphatic group, R 3 is hydrogen or C 1 -C 4 lower alkyl and R 4 is C 1 -C 4 lower alkyl where R 3 and R 4 may be the same or different or together may form a spirocycloalkane or lower alkyl spirocycloalkane with the 2-C of the triazine ring, salts, and acylated derivatives thereof except that R 1 is not an unsubstituted phenyl group when R 2 is unsubstituted and R 1 is not 1-methyl-2 naphthyl when R 2 is ethylene, optionally with another anti-malarial compound such as a sulphonamide and the usual excipients, may be administered orally, parenterally or by suppository.
ES374947A 1969-01-01 1969-12-26 A procedure for the preparation of derivatives of N-substitute symmetrical dihydrotriazine. (Machine-translation by Google Translate, not legally binding) Expired ES374947A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB10269 1969-01-01

Publications (1)

Publication Number Publication Date
ES374947A1 true ES374947A1 (en) 1972-03-16

Family

ID=9698455

Family Applications (1)

Application Number Title Priority Date Filing Date
ES374947A Expired ES374947A1 (en) 1969-01-01 1969-12-26 A procedure for the preparation of derivatives of N-substitute symmetrical dihydrotriazine. (Machine-translation by Google Translate, not legally binding)

Country Status (11)

Country Link
AT (2) AT299214B (en)
BE (1) BE743964A (en)
CH (2) CH555837A (en)
DE (2) DE1965941A1 (en)
ES (1) ES374947A1 (en)
FR (1) FR2027616B1 (en)
GB (1) GB1250531A (en)
NL (1) NL6919621A (en)
OA (1) OA03891A (en)
SE (1) SE388612B (en)
SU (1) SU368752A3 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5322858A (en) * 1992-02-14 1994-06-21 Jacobus Pharmaceutical Co. Inc. N,N'-substituted imidodicarbonimidic diamides derived from hydroxylamines
GB9423515D0 (en) * 1994-11-22 1995-01-11 Zeneca Ltd Fungicidal composition
GR1003549B (en) * 1998-07-13 2001-03-12 Lipophylic speiranic, 4,6 -diamino-symmetric triazines and the respectively salts, their isomers, stereomers and enantiomers, inhibitors of the enzyme of the bihydropholic reductase
AU768570B2 (en) * 1999-07-07 2003-12-18 Fuji Photo Film Co., Ltd. Benzimidazole compounds
US6551614B2 (en) 2001-03-14 2003-04-22 Jacobus Pharmaceutical Co., Inc. Antimalarial N,N′-substituted biguanides derived from hydroxylamines
US7256218B2 (en) 2002-11-22 2007-08-14 Jacobus Pharmaceutical Company, Inc. Biguanide and dihydrotriazine derivatives
DE102008007314A1 (en) * 2008-02-02 2009-08-06 Merck Patent Gmbh Process for the preparation of 3,6-dihydro-1,3,5-triazine derivatives

Also Published As

Publication number Publication date
CH555837A (en) 1974-11-15
DE1965711C3 (en) 1979-04-19
SE388612B (en) 1976-10-11
DE1965941A1 (en) 1970-09-03
AT299217B (en) 1972-06-12
DE1965711B2 (en) 1978-07-13
FR2027616B1 (en) 1974-08-09
DE1965711A1 (en) 1970-09-03
CH556855A (en) 1974-12-13
SU368752A3 (en) 1973-01-26
GB1250531A (en) 1971-10-20
AT299214B (en) 1972-06-12
NL6919621A (en) 1970-07-03
FR2027616A1 (en) 1970-10-02
BE743964A (en) 1970-06-30
OA03891A (en) 1975-08-14

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