ES374399A1 - Procedimiento para la preparacion de derivados de teofili- na. - Google Patents
Procedimiento para la preparacion de derivados de teofili- na.Info
- Publication number
- ES374399A1 ES374399A1 ES374399A ES374399A ES374399A1 ES 374399 A1 ES374399 A1 ES 374399A1 ES 374399 A ES374399 A ES 374399A ES 374399 A ES374399 A ES 374399A ES 374399 A1 ES374399 A1 ES 374399A1
- Authority
- ES
- Spain
- Prior art keywords
- derivatives
- nicotinyl
- hydroxyalkyl
- theophylline
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- ZFXYFBGIUFBOJW-UHFFFAOYSA-N theophylline Chemical compound O=C1N(C)C(=O)N(C)C2=C1NC=N2 ZFXYFBGIUFBOJW-UHFFFAOYSA-N 0.000 title abstract 3
- -1 Pyridinecarbonyl Chemical class 0.000 title 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 title 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 title 1
- 229960000278 theophylline Drugs 0.000 title 1
- ATBIAJXSKNPHEI-UHFFFAOYSA-N pyridine-3-carbonyl chloride Chemical compound ClC(=O)C1=CC=CN=C1 ATBIAJXSKNPHEI-UHFFFAOYSA-N 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000003937 drug carrier Substances 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000008024 pharmaceutical diluent Substances 0.000 abstract 1
- 150000003242 quaternary ammonium salts Chemical class 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB5856368 | 1968-12-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES374399A1 true ES374399A1 (es) | 1972-01-01 |
Family
ID=10481909
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES374399A Expired ES374399A1 (es) | 1968-12-10 | 1969-12-10 | Procedimiento para la preparacion de derivados de teofili- na. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US3565896A (enExample) |
| BE (1) | BE742935A (enExample) |
| DE (1) | DE1961595A1 (enExample) |
| ES (1) | ES374399A1 (enExample) |
| FR (1) | FR2025762B1 (enExample) |
| GB (1) | GB1230663A (enExample) |
| ZA (1) | ZA698550B (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1356789A (en) * | 1970-08-06 | 1974-06-12 | Prodotti Antibiotici Spa | Derivatives of theophylline |
| DE2460929A1 (de) * | 1974-12-21 | 1976-06-24 | Boehringer Sohn Ingelheim | Neue xanthinderivate, verfahren zu ihrer herstellung und ihre anwendung |
| IT1174773B (it) * | 1983-07-29 | 1987-07-01 | Medosan Ind Biochimi | Attivita' antiaggregante piastrinica e broncolitica della 7-(1-metil-5-p-metilbenzoilpirrol-2-acetamidoetil)teofillina |
| GB2331673B (en) * | 1996-07-29 | 2001-02-07 | Ericsson Telefon Ab L M | Method of freeing a voice channel in a radio telecommunications network |
| HUE067314T2 (hu) | 2017-09-22 | 2024-10-28 | Jubilant Epipad LLC | Heterociklusos vegyületek mint PAD gátlók |
| KR102782563B1 (ko) | 2017-10-18 | 2025-03-14 | 주빌런트 에피파드 엘엘씨 | Pad 억제제로서의 이미다조-피리딘 화합물 |
| KR20200085836A (ko) | 2017-11-06 | 2020-07-15 | 주빌런트 프로델 엘엘씨 | Pd1/pd-l1 활성화 억제제로서의 피리미딘 유도체 |
| BR112020010322A2 (pt) | 2017-11-24 | 2020-11-17 | Jubilant Episcribe Llc | composto da fórmula i; composto da fórmula ia; composto da fórmula ib; processo de preparação de compostos da fórmula i; composição farmacêutica; método para o tratamento e/ou prevenção de várias doenças; uso dos compostos; método para o tratamento de câncer; e método para o tratamento e/ou prevenção de uma afecção mediada por prmt5 ou um distúrbio proliferativo ou câncer |
| SG11202008950PA (en) | 2018-03-13 | 2020-10-29 | Jubilant Prodel LLC | Bicyclic compounds as inhibitors of pd1/pd-l1 interaction/activation |
-
1968
- 1968-12-10 GB GB5856368A patent/GB1230663A/en not_active Expired
-
1969
- 1969-12-08 US US883265A patent/US3565896A/en not_active Expired - Lifetime
- 1969-12-08 FR FR696942357A patent/FR2025762B1/fr not_active Expired
- 1969-12-09 ZA ZA698550A patent/ZA698550B/xx unknown
- 1969-12-09 DE DE19691961595 patent/DE1961595A1/de active Pending
- 1969-12-10 ES ES374399A patent/ES374399A1/es not_active Expired
- 1969-12-10 BE BE742935D patent/BE742935A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FR2025762B1 (enExample) | 1973-01-12 |
| US3565896A (en) | 1971-02-23 |
| BE742935A (enExample) | 1970-05-14 |
| GB1230663A (enExample) | 1971-05-05 |
| ZA698550B (en) | 1971-07-28 |
| FR2025762A1 (enExample) | 1970-09-11 |
| DE1961595A1 (de) | 1970-06-25 |
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