ES370345A1 - Improvements in or relating to injectable insulin preparations - Google Patents
Improvements in or relating to injectable insulin preparationsInfo
- Publication number
- ES370345A1 ES370345A1 ES370345A ES370345A ES370345A1 ES 370345 A1 ES370345 A1 ES 370345A1 ES 370345 A ES370345 A ES 370345A ES 370345 A ES370345 A ES 370345A ES 370345 A1 ES370345 A1 ES 370345A1
- Authority
- ES
- Spain
- Prior art keywords
- insulin
- relating
- purified
- injectable preparation
- insulin preparations
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Endocrinology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Diabetes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
A method of manufacturing an injectable preparation of insulin for clinical use, characterized in that crude or commercial insulin is purified, preferably by gel filtration and column chromatography, to the extent that it is free of proteins of pancreatic origin that have a molecular weight greater than approximately 6,000, and shows essentially a single component when analyzed by polyacrylamide gel electrophoresis, and because the insulin thus purified is formulated as an injectable preparation in a manner known per se. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB38081/68A GB1285023A (en) | 1968-08-09 | 1968-08-09 | Improvements in or relating to injectable insulin preparations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES370345A1 true ES370345A1 (en) | 1972-01-01 |
Family
ID=10401047
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES370345A Expired ES370345A1 (en) | 1968-08-09 | 1969-08-08 | Improvements in or relating to injectable insulin preparations |
Country Status (24)
| Country | Link |
|---|---|
| JP (1) | JPS543931B1 (en) |
| AT (1) | AT354634B (en) |
| BE (1) | BE737257A (en) |
| BG (1) | BG25638A3 (en) |
| BR (1) | BR6911403D0 (en) |
| CA (1) | CA920946A (en) |
| CH (1) | CH526958A (en) |
| CS (1) | CS225117B2 (en) |
| CU (1) | CU33401A (en) |
| DE (1) | DE1940130C2 (en) |
| ES (1) | ES370345A1 (en) |
| FR (1) | FR2015369A1 (en) |
| GB (1) | GB1285023A (en) |
| HK (2) | HK51077A (en) |
| IE (1) | IE33239B1 (en) |
| IL (1) | IL32665A (en) |
| KE (2) | KE2774A (en) |
| MT (1) | MTP620B (en) |
| MY (1) | MY7800209A (en) |
| NL (1) | NL141377B (en) |
| PH (1) | PH12571A (en) |
| SE (1) | SE7901917L (en) |
| YU (2) | YU204569A (en) |
| ZM (1) | ZM12069A1 (en) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK140801B (en) * | 1975-01-15 | 1979-11-19 | Nordisk Insulinlab | Process for the preparation of a stable long-acting insulin preparation. |
| DE2505306C2 (en) * | 1975-02-07 | 1984-06-07 | Eli Lilly And Co., Indianapolis, Ind. | Process for purifying an alkali or ammonium insulin |
| NL7713966A (en) * | 1976-12-27 | 1978-06-29 | Univ Minnesota | METHOD OF TREATING INSULIN. |
| DK374579A (en) * | 1979-09-07 | 1981-03-08 | Nordisk Insulinlab | PROCEDURE FOR THE PREPARATION OF AN INJUCABLE INSULIN PREPARATION |
| NL193099C (en) * | 1981-10-30 | 1998-11-03 | Novo Industri As | Stabilized insulin solution. |
| FI78616C (en) * | 1982-02-05 | 1989-09-11 | Novo Industri As | Process for preparing an infused stabilized insulin solution having an elevated zinc content |
| WO1995016708A1 (en) * | 1993-12-17 | 1995-06-22 | Novo Nordisk A/S | Proinsulin-like compounds |
| CO4750643A1 (en) | 1997-06-13 | 1999-03-31 | Lilly Co Eli | STABLE FORMULATION OF INSULIN CONTAINING L-ARGININ AND PROTAMINE |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1940130U (en) | 1966-02-26 | 1966-06-08 | Heinrich Emil Budesheim | DEVICE FOR FILTERING LIQUID OR GAS MEDIA. |
| DE1966573U (en) | 1967-06-01 | 1967-08-17 | Rainer Sahli | CYLINDRICAL LOCK ON DOORS ETC. ROOM LOCKING BODIES. |
-
1968
- 1968-08-09 GB GB38081/68A patent/GB1285023A/en not_active Expired
-
1969
- 1969-07-21 IL IL32665A patent/IL32665A/en unknown
- 1969-07-21 IE IE1012/69A patent/IE33239B1/en unknown
- 1969-07-22 CA CA057646A patent/CA920946A/en not_active Expired
- 1969-07-24 ZM ZM120/69A patent/ZM12069A1/en unknown
- 1969-07-31 CU CU33401A patent/CU33401A/en unknown
- 1969-08-06 CH CH1195769A patent/CH526958A/en not_active IP Right Cessation
- 1969-08-06 YU YU02045/69A patent/YU204569A/en unknown
- 1969-08-06 BG BG012830A patent/BG25638A3/en unknown
- 1969-08-07 FR FR6927255A patent/FR2015369A1/fr not_active Withdrawn
- 1969-08-07 DE DE1940130A patent/DE1940130C2/en not_active Expired
- 1969-08-07 PH PH10600A patent/PH12571A/en unknown
- 1969-08-08 NL NL696912142A patent/NL141377B/en not_active IP Right Cessation
- 1969-08-08 BR BR211403/69A patent/BR6911403D0/en unknown
- 1969-08-08 MT MT620A patent/MTP620B/en unknown
- 1969-08-08 JP JP6283469A patent/JPS543931B1/ja active Pending
- 1969-08-08 ES ES370345A patent/ES370345A1/en not_active Expired
- 1969-08-08 BE BE737257D patent/BE737257A/xx not_active IP Right Cessation
- 1969-08-08 AT AT768769A patent/AT354634B/en not_active IP Right Cessation
- 1969-08-11 CS CS695548A patent/CS225117B2/en unknown
-
1977
- 1977-06-30 YU YU1622/77A patent/YU40003B/en unknown
- 1977-09-13 KE KE2774A patent/KE2774A/en unknown
- 1977-09-29 HK HK510/77A patent/HK51077A/en unknown
- 1977-11-28 KE KE2801A patent/KE2801A/en unknown
- 1977-12-15 HK HK619/77A patent/HK61977A/en unknown
-
1978
- 1978-12-31 MY MY1978209A patent/MY7800209A/en unknown
-
1979
- 1979-03-02 SE SE7901917A patent/SE7901917L/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IE33239B1 (en) | 1974-05-01 |
| NL141377B (en) | 1974-03-15 |
| YU162277A (en) | 1982-05-31 |
| FR2015369A1 (en) | 1970-04-24 |
| ZM12069A1 (en) | 1970-02-16 |
| KE2801A (en) | 1978-01-06 |
| CS225117B2 (en) | 1984-02-13 |
| MTP620B (en) | 1970-01-31 |
| IE33239L (en) | 1970-02-09 |
| DE1940130A1 (en) | 1970-02-12 |
| MY7800209A (en) | 1978-12-31 |
| JPS543931B1 (en) | 1979-02-28 |
| BG25638A3 (en) | 1978-11-10 |
| BR6911403D0 (en) | 1973-03-13 |
| PH12571A (en) | 1979-06-20 |
| YU40003B (en) | 1985-06-30 |
| BE737257A (en) | 1970-02-09 |
| NL6912142A (en) | 1970-02-11 |
| GB1285023A (en) | 1972-08-09 |
| DE1940130C2 (en) | 1983-12-08 |
| YU204569A (en) | 1982-05-31 |
| CU20627L (en) | 1971-08-06 |
| CU33401A (en) | 1971-08-06 |
| CH526958A (en) | 1972-08-31 |
| KE2774A (en) | 1977-10-21 |
| CA920946A (en) | 1973-02-13 |
| IL32665A (en) | 1973-05-31 |
| HK61977A (en) | 1977-12-23 |
| IL32665A0 (en) | 1969-09-25 |
| HK51077A (en) | 1977-10-07 |
| SE7901917L (en) | 1979-03-02 |
| AT354634B (en) | 1979-01-25 |
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