ES446334A1 - Protein having thymus hormone-like activity - Google Patents

Protein having thymus hormone-like activity

Info

Publication number
ES446334A1
ES446334A1 ES446334A ES446334A ES446334A1 ES 446334 A1 ES446334 A1 ES 446334A1 ES 446334 A ES446334 A ES 446334A ES 446334 A ES446334 A ES 446334A ES 446334 A1 ES446334 A1 ES 446334A1
Authority
ES
Spain
Prior art keywords
fractionates
chromatography
molecular weight
protein
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES446334A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syntex USA LLC
Original Assignee
Syntex USA LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/658,200 external-priority patent/US4046877A/en
Application filed by Syntex USA LLC filed Critical Syntex USA LLC
Publication of ES446334A1 publication Critical patent/ES446334A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

A method for the preparation of pre-albumin from human serum, essentially free of impurities, which consists in subjecting the human blood fraction known as the Cohn IV-1 fraction to: a. fractional separation with ammonium sulfate, b. chromatography on a polysaccharide gel column that fractionates the components applied to it by molecular weight, c. repeat step (b) or free flow electrophoresis, d. preparative polyacrylamide gel disc electrophoresis, and e. Chromatography on a micro-column of polysaccharide gel that fractionates the components applied to it by molecular weight. (Machine-translation by Google Translate, not legally binding)
ES446334A 1975-03-24 1976-03-24 Protein having thymus hormone-like activity Expired ES446334A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US56140975A 1975-03-24 1975-03-24
US59711675A 1975-07-18 1975-07-18
US05/658,200 US4046877A (en) 1975-07-18 1976-02-17 Method of increasing immunologic competence

Publications (1)

Publication Number Publication Date
ES446334A1 true ES446334A1 (en) 1977-12-16

Family

ID=27415851

Family Applications (1)

Application Number Title Priority Date Filing Date
ES446334A Expired ES446334A1 (en) 1975-03-24 1976-03-24 Protein having thymus hormone-like activity

Country Status (11)

Country Link
JP (1) JPS51118822A (en)
AU (1) AU509024B2 (en)
CA (1) CA1056305A (en)
DE (1) DE2612015A1 (en)
ES (1) ES446334A1 (en)
FR (1) FR2305191A1 (en)
GB (1) GB1511602A (en)
IE (1) IE43573B1 (en)
NL (1) NL7603020A (en)
NZ (1) NZ180367A (en)
SE (1) SE7603556L (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH075476B2 (en) * 1984-01-12 1995-01-25 ルッシュ、フォルケル Biological agent having hormonal activity, process for its production and histone medicinal use

Also Published As

Publication number Publication date
NL7603020A (en) 1976-09-28
FR2305191A1 (en) 1976-10-22
DE2612015A1 (en) 1976-10-14
GB1511602A (en) 1978-05-24
JPS51118822A (en) 1976-10-19
IE43573B1 (en) 1981-04-08
AU1230876A (en) 1977-09-29
FR2305191B1 (en) 1978-11-17
CA1056305A (en) 1979-06-12
SE7603556L (en) 1976-10-22
NZ180367A (en) 1978-07-28
AU509024B2 (en) 1980-04-17
IE43573L (en) 1976-09-24

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