ES368100A1 - New sulphonamides having a blood sugar lowering action - Google Patents

New sulphonamides having a blood sugar lowering action

Info

Publication number
ES368100A1
ES368100A1 ES368100A ES368100A ES368100A1 ES 368100 A1 ES368100 A1 ES 368100A1 ES 368100 A ES368100 A ES 368100A ES 368100 A ES368100 A ES 368100A ES 368100 A1 ES368100 A1 ES 368100A1
Authority
ES
Spain
Prior art keywords
alkyl
blood sugar
lowering action
sugar lowering
carbons
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES368100A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Publication of ES368100A1 publication Critical patent/ES368100A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/69Benzenesulfonamido-pyrimidines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Pharmaceutical preparations having antidiabetic action contain as active ingredient compounds I (including salts with bases thereof) wherein R 1 and R 2 are H, halogen or C, to 4 alkyl, alkoxy or alkylmercapto, R 3 is alkyl or cycloalkyl with up to 8 carbons which may be interrupted by at least one oxygen or is alkoxy or cycloalkoxy with up to 8 carbons in which the alkyl or cycloalkyl fragment thereof may be interrupted by at least one oxygen, R 4 is H or C 1 to 4 alkyl, X signifies O, S or NH, Y is C 1 to 4 alkylene and n is 0 to 1 to 4. Bases, e.g. butyl biguanide, for salt formation may also possess a blood sugar-lowering action. Administration may be in the form of tablets, dragees, capsules, pills, suspensions or solutions.
ES368100A 1968-06-27 1969-06-06 New sulphonamides having a blood sugar lowering action Expired ES368100A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19681770731 DE1770731A1 (en) 1968-06-27 1968-06-27 New blood sugar lowering sulfonamides

Publications (1)

Publication Number Publication Date
ES368100A1 true ES368100A1 (en) 1971-05-01

Family

ID=5700618

Family Applications (1)

Application Number Title Priority Date Filing Date
ES368100A Expired ES368100A1 (en) 1968-06-27 1969-06-06 New sulphonamides having a blood sugar lowering action

Country Status (14)

Country Link
AT (3) AT291256B (en)
BE (1) BE735287A (en)
BR (1) BR6908777D0 (en)
CH (1) CH518968A (en)
DE (1) DE1770731A1 (en)
DK (1) DK123602B (en)
ES (1) ES368100A1 (en)
FR (1) FR2014300B1 (en)
GB (1) GB1268835A (en)
IE (1) IE33175B1 (en)
IL (1) IL32396A (en)
NL (1) NL6909960A (en)
NO (1) NO124374B (en)
SE (1) SE357365B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2048906A1 (en) * 1970-10-06 1972-04-13 Boehringer Mannheim Gmbh, 6800 Mannheim Blood sugar lowering sulfonylaminopyrimidines and processes for their preparation
AU2003232551A1 (en) * 2002-06-13 2003-12-31 Qlt Inc. Methods of using isothiazole derivatives to treat cancer or inflammation

Also Published As

Publication number Publication date
IE33175L (en) 1969-12-27
DK123602B (en) 1972-07-10
IE33175B1 (en) 1974-04-03
AT289109B (en) 1971-04-13
CH518968A (en) 1972-02-15
BE735287A (en) 1969-12-29
NL6909960A (en) 1969-12-30
FR2014300B1 (en) 1973-01-12
AT291256B (en) 1971-07-12
IL32396A (en) 1972-06-28
GB1268835A (en) 1972-03-29
SE357365B (en) 1973-06-25
NO124374B (en) 1972-04-10
IL32396A0 (en) 1969-08-27
DE1770731A1 (en) 1971-11-25
AT291255B (en) 1971-07-12
BR6908777D0 (en) 1973-01-23
FR2014300A1 (en) 1970-04-17

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