ES373657A1 - Di-hydro triazine derivatives and processes for their manufacture - Google Patents

Di-hydro triazine derivatives and processes for their manufacture

Info

Publication number
ES373657A1
ES373657A1 ES373657A ES373657A ES373657A1 ES 373657 A1 ES373657 A1 ES 373657A1 ES 373657 A ES373657 A ES 373657A ES 373657 A ES373657 A ES 373657A ES 373657 A1 ES373657 A1 ES 373657A1
Authority
ES
Spain
Prior art keywords
alkyl
optionally substituted
hydro
manufacture
processes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES373657A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of ES373657A1 publication Critical patent/ES373657A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/08—1,3-Dioxanes; Hydrogenated 1,3-dioxanes condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/04—Saturated ethers
    • C07C43/12—Saturated ethers containing halogen
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16J—PISTONS; CYLINDERS; SEALINGS
    • F16J1/00—Pistons; Trunk pistons; Plungers
    • F16J1/10—Connection to driving members
    • F16J1/14—Connection to driving members with connecting-rods, i.e. pivotal connections

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Combustion & Propulsion (AREA)
  • Mechanical Engineering (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Pharmaceutical preparations having antimicrobial, especially anti-malarial activity contain I (including acylates, amine-imine tautomers, isomers and salts thereof) as active ingredient (R 1 is optionally substituted hydrocarbon or heterocyclic radical, X is O, S or NR 5 where R 5 is H or optionally substituted alkyl or aralkyl, R 2 is an optionally substituted C 1 to 16 divalent aliphatic group, R 3 is H or alkyl, R 4 is alkyl or R 3 and R 4 together may comprise an optionally alkyl substituted spirocycloalkane, except that when X is O, R 1 is not 4, 6-diamino-1, 2-dihydro-2- R 3 -2-R 4 -1, 3, 5-triazin-1-yl). In particular, other anti-malarials, e.g. sulphonamides, can be incorporated in the preparations. Administration may be by suppository or orally or parenterally.
ES373657A 1968-11-22 1969-11-18 Di-hydro triazine derivatives and processes for their manufacture Expired ES373657A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB5542868 1968-11-22
GB01866/69A GB1270831A (en) 1968-11-22 1968-11-22 Di-hydro triazine derivatives and processes for their manufacture

Publications (1)

Publication Number Publication Date
ES373657A1 true ES373657A1 (en) 1972-02-01

Family

ID=26248577

Family Applications (1)

Application Number Title Priority Date Filing Date
ES373657A Expired ES373657A1 (en) 1968-11-22 1969-11-18 Di-hydro triazine derivatives and processes for their manufacture

Country Status (13)

Country Link
AT (1) AT303748B (en)
BE (1) BE741996A (en)
CH (1) CH554350A (en)
DE (2) DE1957769C3 (en)
DK (1) DK134521B (en)
ES (1) ES373657A1 (en)
FR (1) FR2023866B1 (en)
GB (1) GB1270831A (en)
LU (1) LU59866A1 (en)
NL (1) NL6917536A (en)
NO (1) NO128712B (en)
OA (1) OA03394A (en)
SE (1) SE383883B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL41744A0 (en) * 1972-03-16 1973-05-31 Ciba Geigy Ag New aryl ether derivatives,their production and their use as pesticides
US5322858A (en) * 1992-02-14 1994-06-21 Jacobus Pharmaceutical Co. Inc. N,N'-substituted imidodicarbonimidic diamides derived from hydroxylamines
GB9423515D0 (en) * 1994-11-22 1995-01-11 Zeneca Ltd Fungicidal composition
US6551614B2 (en) 2001-03-14 2003-04-22 Jacobus Pharmaceutical Co., Inc. Antimalarial N,N′-substituted biguanides derived from hydroxylamines

Also Published As

Publication number Publication date
NO128712B (en) 1974-01-02
FR2023866B1 (en) 1974-01-11
DE1957769B2 (en) 1979-12-20
SE383883B (en) 1976-04-05
OA03394A (en) 1970-12-15
DE1957769C3 (en) 1980-08-28
GB1270831A (en) 1972-04-19
DE1965925A1 (en) 1970-09-17
FR2023866A1 (en) 1970-08-21
DK134521C (en) 1977-04-25
DK134521B (en) 1976-11-22
CH554350A (en) 1974-09-30
BE741996A (en) 1970-05-20
LU59866A1 (en) 1970-01-21
DE1957769A1 (en) 1970-09-17
NL6917536A (en) 1970-05-26
AT303748B (en) 1972-12-11

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