GB1268835A - New sulphonamides having a blood sugar lowering action - Google Patents

New sulphonamides having a blood sugar lowering action

Info

Publication number
GB1268835A
GB1268835A GB30406/69A GB3040669A GB1268835A GB 1268835 A GB1268835 A GB 1268835A GB 30406/69 A GB30406/69 A GB 30406/69A GB 3040669 A GB3040669 A GB 3040669A GB 1268835 A GB1268835 A GB 1268835A
Authority
GB
United Kingdom
Prior art keywords
alkyl
blood sugar
lowering action
sugar lowering
carbons
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB30406/69A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Publication of GB1268835A publication Critical patent/GB1268835A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/69Benzenesulfonamido-pyrimidines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1,268,835. Anti-diabetic sulpha-pyrimidines. SCHERING A.G. 16 June, 1969 [27 June, 1968], No. 30406/69. Heading A5B. [Also in Division C2] Pharmaceutical preparations having antidiabetic action contain as active ingredient compounds I (including salts with bases thereof) wherein R 1 and R 2 are H, halogen or C, to 4 alkyl, alkoxy or alkylmercapto, R 3 is alkyl or cycloalkyl with up to 8 carbons which may be interrupted by at least one oxygen or is alkoxy or cycloalkoxy with up to 8 carbons in which the alkyl or cycloalkyl fragment thereof may be interrupted by at least one oxygen, R 4 is H or C 1 to 4 alkyl, X signifies O, S or NH, Y is C 1 to 4 alkylene and n is 0 to 1 to 4. Bases, e.g. butyl biguanide, for salt formation may also possess a blood sugar-lowering action. Administration may be in the form of tablets, dragees, capsules, pills, suspensions or solutions.
GB30406/69A 1968-06-27 1969-06-16 New sulphonamides having a blood sugar lowering action Expired GB1268835A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19681770731 DE1770731A1 (en) 1968-06-27 1968-06-27 New blood sugar lowering sulfonamides

Publications (1)

Publication Number Publication Date
GB1268835A true GB1268835A (en) 1972-03-29

Family

ID=5700618

Family Applications (1)

Application Number Title Priority Date Filing Date
GB30406/69A Expired GB1268835A (en) 1968-06-27 1969-06-16 New sulphonamides having a blood sugar lowering action

Country Status (14)

Country Link
AT (3) AT291256B (en)
BE (1) BE735287A (en)
BR (1) BR6908777D0 (en)
CH (1) CH518968A (en)
DE (1) DE1770731A1 (en)
DK (1) DK123602B (en)
ES (1) ES368100A1 (en)
FR (1) FR2014300B1 (en)
GB (1) GB1268835A (en)
IE (1) IE33175B1 (en)
IL (1) IL32396A (en)
NL (1) NL6909960A (en)
NO (1) NO124374B (en)
SE (1) SE357365B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003105843A1 (en) * 2002-06-13 2003-12-24 Kinetek Pharmaceuticals, Inc. Methods of using isothiazole derivatives to treat cancer or inflammation

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2048906A1 (en) * 1970-10-06 1972-04-13 Boehringer Mannheim Gmbh, 6800 Mannheim Blood sugar lowering sulfonylaminopyrimidines and processes for their preparation

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003105843A1 (en) * 2002-06-13 2003-12-24 Kinetek Pharmaceuticals, Inc. Methods of using isothiazole derivatives to treat cancer or inflammation

Also Published As

Publication number Publication date
IE33175L (en) 1969-12-27
DK123602B (en) 1972-07-10
IE33175B1 (en) 1974-04-03
AT289109B (en) 1971-04-13
CH518968A (en) 1972-02-15
BE735287A (en) 1969-12-29
NL6909960A (en) 1969-12-30
FR2014300B1 (en) 1973-01-12
AT291256B (en) 1971-07-12
IL32396A (en) 1972-06-28
SE357365B (en) 1973-06-25
NO124374B (en) 1972-04-10
IL32396A0 (en) 1969-08-27
ES368100A1 (en) 1971-05-01
DE1770731A1 (en) 1971-11-25
AT291255B (en) 1971-07-12
BR6908777D0 (en) 1973-01-23
FR2014300A1 (en) 1970-04-17

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