GB1336983A - Sulphonyl-ureas and sulphonyl-semicarbazides - Google Patents

Sulphonyl-ureas and sulphonyl-semicarbazides

Info

Publication number
GB1336983A
GB1336983A GB3236472A GB3236472A GB1336983A GB 1336983 A GB1336983 A GB 1336983A GB 3236472 A GB3236472 A GB 3236472A GB 3236472 A GB3236472 A GB 3236472A GB 1336983 A GB1336983 A GB 1336983A
Authority
GB
United Kingdom
Prior art keywords
radical
sulphonyl
alkyl
saturated
ureas
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3236472A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of GB1336983A publication Critical patent/GB1336983A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/20—Spiro-condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/18—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C07D295/28—Nitrogen atoms
    • C07D295/32—Nitrogen atoms acylated with carboxylic or carbonic acids, or their nitrogen or sulfur analogues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

1336983 Sulphonyl-ureas BOEHRINGER MANNHEIM GmbH 11 July 1972 [17 July 1971] 32364/72 Heading C2C Novel compounds (I) (including salts thereof) wherein A is an aryl, aralkyl, furyl, thienyl or isoxazolyl radical, optionally substituted by halogen atoms or alkyl, alkoxy or alkoxyalkoxy radicals containing up to 3 carbon atoms, R 1 is a hydrogen atom or a C 1 to C 5 alkyl radical R 2 is a straight-chained or branched, saturated or unsaturated aliphatic hydrocarbon radical, a saturated or unsaturated cycloaliphatic hydrocarbon radical, optionally substituted by alkyl or alkoxy radicals, the radical of an unsubstituted or substituted bi- or polycyclic hydrocarbon or an optionally alkyl-substituted, saturated or unsaturated alkyleneimine radical, which can also contain an endoalkylene group with up to 3 carbon atoms or can be connected spiro-like with a further alkylene radical, are made according to standard methods, especially via the corresponding -SO 2 Cl and -SO 2 NH 2 compounds and sulphonyl-urethanes. 5 - Methyl - isoxazole - 3 - carboxylic acid chloride and N - {(2 - amino - and - ethoxycarbonylamino) - 1,2,3,4 - tetrahydronaphthalene- 7 - sulphonyl} - N<SP>1</SP> - cyclohexyl - ureas are also described. Pharmaceutical preparations showing antidiabetic action contain (I) as active ingredient; administration may be enterally or parenterally.
GB3236472A 1971-07-17 1972-07-11 Sulphonyl-ureas and sulphonyl-semicarbazides Expired GB1336983A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19712135805 DE2135805A1 (en) 1971-07-17 1971-07-17 Blood sugar lowering sulphonyl urea and sulphonyl semicarbocides and the process for their manufacture

Publications (1)

Publication Number Publication Date
GB1336983A true GB1336983A (en) 1973-11-14

Family

ID=5813987

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3236472A Expired GB1336983A (en) 1971-07-17 1972-07-11 Sulphonyl-ureas and sulphonyl-semicarbazides

Country Status (6)

Country Link
AT (2) AT320661B (en)
CH (2) CH583187A5 (en)
DE (1) DE2135805A1 (en)
FR (1) FR2146260B1 (en)
GB (1) GB1336983A (en)
SE (1) SE382632B (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1300142A1 (en) * 2000-07-05 2003-04-09 Ajinomoto Co., Inc. Hypoglycemics
US6555584B1 (en) * 2000-06-29 2003-04-29 Ajinomoto Co., Inc. Acylsulfonamide derivative
JP2004518722A (en) * 2001-02-13 2004-06-24 アベンティス・ファーマ・ドイチユラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング Acylated 1,2,3,4-tetrahydronaphthylamine and its use as a medicament

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6555584B1 (en) * 2000-06-29 2003-04-29 Ajinomoto Co., Inc. Acylsulfonamide derivative
EP1300142A1 (en) * 2000-07-05 2003-04-09 Ajinomoto Co., Inc. Hypoglycemics
EP1300142A4 (en) * 2000-07-05 2004-05-19 Ajinomoto Kk Hypoglycemics
JP2004518722A (en) * 2001-02-13 2004-06-24 アベンティス・ファーマ・ドイチユラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング Acylated 1,2,3,4-tetrahydronaphthylamine and its use as a medicament

Also Published As

Publication number Publication date
FR2146260B1 (en) 1975-10-17
SE382632B (en) 1976-02-09
DE2135805A1 (en) 1973-02-08
AT320661B (en) 1975-02-25
FR2146260A1 (en) 1973-03-02
CH583187A5 (en) 1976-12-31
AT324350B (en) 1975-08-25
CH577468A5 (en) 1976-07-15

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee