ES362794A1 - Procedimiento para la obtencion de espiro (1,3)-benzodioxol-2,3-pirrolidina. - Google Patents
Procedimiento para la obtencion de espiro (1,3)-benzodioxol-2,3-pirrolidina.Info
- Publication number
- ES362794A1 ES362794A1 ES362794A ES362794A ES362794A1 ES 362794 A1 ES362794 A1 ES 362794A1 ES 362794 A ES362794 A ES 362794A ES 362794 A ES362794 A ES 362794A ES 362794 A1 ES362794 A1 ES 362794A1
- Authority
- ES
- Spain
- Prior art keywords
- reacting
- iii
- prepared
- xch
- phch
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000543 intermediate Substances 0.000 title 1
- OUJKSHSWNVQPCI-UHFFFAOYSA-N spiro[1,3-benzodioxole-2,3'-pyrrolidine] Chemical compound C1NCCC21OC1=CC=CC=C1O2 OUJKSHSWNVQPCI-UHFFFAOYSA-N 0.000 title 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 abstract 4
- 229910010082 LiAlH Inorganic materials 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- YCIMNLLNPGFGHC-UHFFFAOYSA-N catechol Chemical compound OC1=CC=CC=C1O YCIMNLLNPGFGHC-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- FTNJQNQLEGKTGD-UHFFFAOYSA-N 1,3-benzodioxole Chemical compound C1=CC=C2OCOC2=C1 FTNJQNQLEGKTGD-UHFFFAOYSA-N 0.000 abstract 1
- OHUZDYSSDJKBLQ-UHFFFAOYSA-N 2,2-dibromobutanedioic acid Chemical compound OC(=O)CC(Br)(Br)C(O)=O OHUZDYSSDJKBLQ-UHFFFAOYSA-N 0.000 abstract 1
- SLRMQYXOBQWXCR-UHFFFAOYSA-N 2154-56-5 Chemical compound [CH2]C1=CC=CC=C1 SLRMQYXOBQWXCR-UHFFFAOYSA-N 0.000 abstract 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- YTIVTFGABIZHHX-UHFFFAOYSA-N butynedioic acid Chemical compound OC(=O)C#CC(O)=O YTIVTFGABIZHHX-UHFFFAOYSA-N 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 125000004177 diethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 125000000118 dimethyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 150000003254 radicals Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH111868A CH497454A (de) | 1968-01-24 | 1968-01-24 | Verfahren zur Herstellung von 1',2',4',5'-Tetrahydrospiro (1,3-benzodioxol-2,3'-pyrrol) |
| CH519268 | 1968-04-08 | ||
| CH796168 | 1968-05-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES362794A1 true ES362794A1 (es) | 1971-02-16 |
Family
ID=27172712
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES362794A Expired ES362794A1 (es) | 1968-01-24 | 1969-01-22 | Procedimiento para la obtencion de espiro (1,3)-benzodioxol-2,3-pirrolidina. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US3560522A (en)) |
| BE (1) | BE727330A (en)) |
| DE (1) | DE1903035C3 (en)) |
| ES (1) | ES362794A1 (en)) |
| FR (1) | FR2000649A1 (en)) |
| GB (1) | GB1241512A (en)) |
| NL (1) | NL6818875A (en)) |
| SE (1) | SE349586B (en)) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL128667A (en) * | 1996-08-28 | 2002-04-21 | Procter & Gamble | Spirocyclic metroprotease inhibitors and pharmaceutical preparations containing them |
-
1968
- 1968-12-31 NL NL6818875A patent/NL6818875A/xx unknown
-
1969
- 1969-01-03 SE SE00061/69A patent/SE349586B/xx unknown
- 1969-01-08 GB GB0136/69A patent/GB1241512A/en not_active Expired
- 1969-01-15 US US791509*A patent/US3560522A/en not_active Expired - Lifetime
- 1969-01-22 ES ES362794A patent/ES362794A1/es not_active Expired
- 1969-01-22 DE DE1903035A patent/DE1903035C3/de not_active Expired
- 1969-01-23 FR FR6901206A patent/FR2000649A1/fr not_active Withdrawn
- 1969-01-23 BE BE727330D patent/BE727330A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NL6818875A (en)) | 1969-07-28 |
| GB1241512A (en) | 1971-08-04 |
| FR2000649A1 (en)) | 1969-09-12 |
| SE349586B (en)) | 1972-10-02 |
| BE727330A (en)) | 1969-07-23 |
| US3560522A (en) | 1971-02-02 |
| DE1903035B2 (en)) | 1974-05-30 |
| DE1903035C3 (de) | 1975-02-20 |
| DE1903035A1 (de) | 1969-08-21 |
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